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C-Peptide

The middle segment of proinsulin that is between the N-terminal B-chain and the C-terminal A-chain. It is a pancreatic peptide of about 31 residues, depending on the species. Upon proteolytic cleavage of proinsulin, equimolar INSULIN and C-peptide are released. C-peptide immunoassay has been used to assess pancreatic beta cell function in diabetic patients with circulating insulin antibodies or exogenous insulin. Half-life of C-peptide is 30 min, almost 8 times that of insulin.
Also Known As:
C-Peptide, Proinsulin; Connecting Peptide; C Peptide; C Peptide, Proinsulin; Proinsulin C Peptide; Proinsulin C-Peptide
Networked: 2442 relevant articles (103 outcomes, 269 trials/studies)

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Experts

1. Sima, Anders A F: 19 articles (10/2009 - 09/2003)
2. Kaaks, Rudolf: 17 articles (11/2014 - 02/2003)
3. Pollak, Michael N: 14 articles (01/2015 - 04/2005)
4. Fuchs, Charles S: 13 articles (01/2015 - 01/2005)
5. Rinaldi, Sabina: 13 articles (04/2013 - 02/2003)
6. Ma, Jing: 12 articles (01/2015 - 04/2004)
7. Riboli, Elio: 12 articles (11/2014 - 04/2003)
8. Marx, Nikolaus: 11 articles (09/2015 - 03/2004)
9. Hankinson, Susan E: 11 articles (10/2013 - 09/2003)
10. Giovannucci, Edward: 11 articles (04/2013 - 02/2004)

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