Butoxamine (Butaxamine)

A beta-2 selective adrenergic antagonist. It is used primarily in animal and tissue experiments to characterize BETA-2 ANDRENERGIC RECEPTORS.
Also Known As:
Butaxamine; Butoxamine Hydrochloride; Hydrochloride, Butoxamine; Benzenemethanol, alpha-(1-((1,1-dimethylethyl)amino)ethyl)-2,5-dimethoxy-
Networked: 26 relevant articles (3 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Liu, Tong: 2 articles (12/2015 - 04/2015)
2. Peng, Xiao-Yan: 1 article (12/2015)
3. Wang, Xue-Long: 1 article (12/2015)
4. Chen, Li-Hua: 1 article (12/2015)
5. Cao, Lei-Fang: 1 article (12/2015)
6. Luo, Wei-Feng: 1 article (12/2015)
7. Huang, Ya: 1 article (12/2015)
8. Jiang, Xinghong: 1 article (04/2015)
9. Zhou, Youlang: 1 article (04/2015)
10. Wang, Shusheng: 1 article (04/2015)

Related Diseases

1. Ulcer
2. Cardiac Arrhythmias (Arrythmia)
3. Airway Obstruction (Choking)
4. Tremor (Tremors)
10/01/1986 - "A comparative study of the antitremor activity of beta-adrenoceptor antagonists against this tremor-model showed that butoxamine (beta 2-antagonist) and propranolol (nonselective antagonist) were able to afford a rapid and powerful protection, whereas a weaker and delayed effect was observed in rats treated with the beta 1-antagonist, acebutolol. "
03/11/1986 - "The dose of isoprenaline (0.1 mg/kg) that markedly reduced the effect of butoxamine did not alter the effect of acebutolol, suggesting that antagonism of peripheral beta 1-adrenoceptor was not responsible for the antitremor action of acebutolol and that blockade of peripheral beta 2-receptors is involved to a great extent in the inhibition of tremors by butoxamine. "
03/11/1986 - "Specific beta 1- and beta 2-adrenoceptor antagonists, acebutolol and butoxamine respectively were used to investigate the involvement of blockade of these receptors in the inhibition of harmaline-induced tremors. "
10/01/1986 - "It was inferred that beta 2-receptor modulated the tremorogenic activity of tremorine, and that inhibition by propranolol or butoxamine of this subtype beta-adrenoceptor resulted in rapid and powerful suppression of tremors, and that the antiadrenergic activity of acebutolol was unlikely to have a role in its antitremor effect."
03/01/1993 - "To investigate what property of beta-blockers plays the main role in suppressing tremor, we employed five beta-blockers (propranolol, atenolol, butoxamine, pindolol, and arotinolol). "
5. Inflammation

Related Drugs and Biologics

1. Propranolol (Inderal)
2. Atenolol (Tenormin)
3. Dinoprostone (PGE2)
4. Indomethacin (Indometacin)
5. Metoprolol (Lopressor)
6. Phentolamine (Z-Max)
7. Adrenergic Antagonists (Antiadrenergic Agents)
8. Terbutaline (Brethaire)
9. Epinephrine (Adrenaline)
10. Albuterol (Salbutamol)

Related Therapies and Procedures

1. Oral Administration
2. Intraperitoneal Injections
3. Drug Therapy (Chemotherapy)