Chemical Burns (Chemical Burn)

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343 relevant articles (5 outcomes, 16 trials/studies) found for this Disease

Also Known As:

Chemical Burn; Burn, Chemical; Burns, Chemical

Relationship Network

Disease Context: Research Results

Disorders of Environmental Origin

Wounds and Injuries: 60713

Burns: 13666

Chemical Burns: 343

Related Diseases

1.	Inflammation
2.	Corneal Neovascularization
3.	Conjunctival Diseases
4.	Wounds and Injuries (Trauma)
5.	Burns

Experts

1.	Singh, G: 1 article (07/2008)
2.	Singh Bhinder, H: 1 article (07/2008)
3.	Yoeruek, Efdal: 1 article (05/2008)
4.	Tura, Aysegül: 1 article (05/2008)
5.	Bartz-Schmidt, Karl U: 1 article (05/2008)
6.	Grisanti, Salvatore: 1 article (05/2008)
7.	Tübingen Bevacizumab Study Group: 1 article (05/2008)
8.	Szurman, Peter: 1 article (05/2008)
9.	Ziemssen, Focke: 1 article (05/2008)
10.	Henke-Fahle, Sigrid: 1 article (05/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chemical Burns:

1.	Phenol (Carbolic Acid)IBA 05/01/2001 - "Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin." 04/01/1993 - "The highest concentrations of TCA and phenol may cause full-thickness facial chemical burns and leave long-lasting scars" 01/01/1993 - "The absence of serious toxicity and major chemical burns in this series does not eliminate concern with the corrosive and systemic risks of phenol poisoning." 03/01/1997 - "As water evaporates much faster than phenol, the solution on stored mops/ brushes, etc. becomes progressively more and more concentrated and can cause chemical burns when these utensils are handled at a later time" 02/01/1985 - "Adverse reactions to phenol-formaldehyde resins include depigmentation, irritant dermatitis, chemical burns and allergic contact dermatitis" Order ALL the reference details at left...
2.	Ophthalmic Solutions (Eye Drops)IBA 01/01/1987 - "Use of cyclosporin A eyedrops in the treatment of severe chemical burns]" 02/01/2008 - "METHODS: Patients with aggressive corneal neovascularisation not responding to conventional therapy were treated with bevacizumab (Avastin) eye drops (5x/day; 5 mg/ml) for 0.5 to 6 months (mean: 3.6 +/- 2; four patients with limbal stem cell deficiency [three due to chemical burns and one inherited] and one after perforating keratoplasty)" 05/01/2008 - "Safety, penetration and efficacy of topically applied bevacizumab: evaluation of eyedrops in corneal neovascularization after chemical burn." Order ALL the reference details at left...
3.	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/01/1992 - "Our current conclusions are that (1) immune reactions are efficiently inhibited with constantly effective blood levels of cyclosporin A, which has enormously increased the rate of keratoplasty successful in these patients; (2) if drug blood levels fall too low due to noncompliance of the patient or to metabolic disturbances, immune reactions may occur, especially during the early postoperative months; (3) serious chronic surface problems, which are especially associated with chemical burns, atopic inflammation, and other chronic kerato-conjunctival diseases, are partly ameliorated but not completely eliminated (surface disorders are presently ranked as the number one cause of transplant failure, whereas immune reactions can be effectively suppressed by cyclosporin A); and (4) close medical follow-up has revealed no serious systemic complication of cyclosporin A prophylaxis over periods of up to 37 months" 01/01/1987 - "Use of cyclosporin A eyedrops in the treatment of severe chemical burns]" Order ALL the reference details at left...
4.	bevacizumab FDA Link 02/01/2008 - "METHODS: Patients with aggressive corneal neovascularisation not responding to conventional therapy were treated with bevacizumab (Avastin) eye drops (5x/day; 5 mg/ml) for 0.5 to 6 months (mean: 3.6 +/- 2; four patients with limbal stem cell deficiency [three due to chemical burns and one inherited] and one after perforating keratoplasty)" 05/01/2008 - "Safety, penetration and efficacy of topically applied bevacizumab: evaluation of eyedrops in corneal neovascularization after chemical burn." Order ALL the reference details at left...
5.	AlkaliesIBA 06/01/2001 - "The mean age was 25 years and the male to female ratio was 3:1. Alkali drain cleaners were the major cause of chemical burns in the series and this was seen in 75% of the total study population" 06/01/1986 - "Value of an amphoteric isotonic solution in the early treatment of corneoconjunctival alkali chemical burns: experimental and histological study]" 06/01/2001 - "It was concluded that efforts for prevention of chemical burns in Saudi Arabia should be directed towards education of the population regarding the proper use of alkali cleaners for clogged drains" 09/01/1994 - "This case exemplifies why alkali chemical burns from an automotive airbag should be treated aggressively, despite their benign appearance, as they may take several days to evolve" 01/01/1991 - "It is proposed that in a chemical burn of the cornea, alkali is both stored in the tissue (by sorption) and reacted with it (by hydrolysis), without any net consumption of alkali taking place." Order ALL the reference details at left...
6.	Phosphorus (Red Phosphorus)IBA 08/01/2004 - "In this study, we compare incidence, cause and outcome of chemical burn injury over time and review the management of white phosphorus injuries" 08/01/2004 - "Over a 51-year period, we have treated 276 patients with chemical burn injury including 146 white phosphorus injuries" 08/01/2004 - "Treatment of white phosphorus and other chemical burn injuries at one burn center over a 51-year period." 08/01/2001 - "Phosphorus burns are a rarely encountered chemical burn, typically occurring in battle, industrial accidents, or from fireworks" 05/01/1973 - "Alkaline phosphatase and inorganic phosphorus content in the cornea after a chemical burn]" Order ALL the reference details at left...
7.	Polyethylene (Polythene)IBA 09/01/1970 - "The effect of treating chemical burns and other esophageal injuries with a polyethylene bougie (experimental-clinical study)]" 11/01/1973 - "Inflatable polyethylene dilator-sound with a nylon mesh cover for dilating the esophagus and for the local use of corticosteroids and antibiotics in the treatment of severe chemical burns of the esophagus]" Order ALL the reference details at left...
8.	Mechlorethamine (Nitrogen Mustard)FDA Link 05/01/2003 - "These parallel studies further establish that mice deficient in CXCR2 function exhibit delayed cutaneous wound healing that may be primarily linked to impaired neutrophil recruitment after chemical burn with nitrogen mustard" 05/01/2003 - "To examine the significance of chemokine activation of CXCR2 in wound healing after chemical burn, cutaneous injury was created by topical application of nitrogen mustard on CXCR2 wild type (+/+), heterozygous (+/-), and knockout (-/-) mice" 03/01/1998 - "Chemical burns were inflicted with nitrogen mustard (NM -- a nitrogen analog to sulfur mustard -- mustard gas) in an experimental guinea pig model" Order ALL the reference details at left...
9.	CortisoneIBA 12/01/1956 - "Histological studies on an esophagus treated with cortisone for chemical burns.]" 02/01/1954 - "Chemical burn of the esophagus; report of a case treated with cortisone and penicillin." Order ALL the reference details at left...
10.	mofezolac (N 22)IBA 03/01/2004 - "METHODS: In total, 20 patients (n=22 eyes) with chemical burn and two patients (n=2 eyes) with thermal burn were included in this study" 04/01/2005 - "SUBJECTS AND METHOD: A total of 197 eyes were divided into 9 groups: group 1, Cogan dystrophy including recurrences (n = 15); group 2, Reis Bucklers dystrophy including recurrences (n = 12); group 3, granular dystrophy including recurrences (n = 63); group 4, lattice dystrophy including recurrences (n = 19); group 5, macular dystrophy including recurrences (n = 10); group 6, herpetic scars (n = 5); group 7, corneal scars of nonherpetic origin (including scrofulous, traumatic, central keratoconus, post-pterygium surgery) (n = 31); group 8, Salzmann nodular degeneration (n = 22); and group 9, miscellaneous (such as bullous keratopathy, acute chemical burn, corneal degeneration) (n = 20)" Order ALL the reference details at left...

Therapies and Procedures

1.	Transplantation (Transplant Recipients) 09/01/2001 - "PURPOSE: A histopathological study to investigate the efficacy of conjunctival auto-transplantation on alkaline chemical burns of the ocular surface" 09/01/2008 - "RESULTS: Twenty-eight patients with corneal surface disorders due to severe chemical burns, corneal ulceration, or persistent epithelium defects were treated with amniotic membrane transplantation" 12/01/2006 - "A 12-year-old girl with total limbal stem cell deficiency in the right eye following chemical burns underwent autologous cultivated limbal epithelium transplantation from the healthy left eye" 01/01/2006 - "Effect of transplantation of cultured human neural stem and progenitor cells on regeneration of the cornea after chemical burn." 03/01/2005 - "PURPOSE: To evaluate the outcome of fresh amniotic membrane transplantation (AMT) for ocular surface reconstruction in acute chemical burns" Order ALL the reference details at left...
2.	Transplants (Transplant) 09/01/2002 - "In this study, MMP-2 and MMP-9 expression was analyzed by in situ zymography on rabbit corneal chemical burns with and without human amniotic membrane graft" 06/01/2006 - "The indications for the PBIKP were chemical burns (11 cases); highly vascularized failed grafts (11 cases); severe dry eyes with total vascularized cornea (6 cases); miscellaneous (3 cases)" 05/01/2006 - "Modified gunderson conjunctival flap combined with an oral mucosal graft to treat an intractable corneal lysis after chemical burn: a case report." 06/01/2004 - "Split calvarial bone graft procedure for the nasal tip projection reconstruction was performed for five patients, all of whom had sustained chemical burns following assault by strong acid" 06/01/2004 - "Split calvarial bone graft for chemical burn-associated nasal augmentation." Order ALL the reference details at left...
3.	Corneal Transplantation (Keratoplasty) 07/01/2008 - "PURPOSE: To evaluate the role of deep anterior lamellar keratoplasty (DALK) in acute ocular chemical burns" 07/01/2008 - "Evaluation of therapeutic deep anterior lamellar keratoplasty in acute ocular chemical burns." 12/01/2003 - "CONCLUSION: Full layer eyelid defect caused by chemical burn should receive early reconstruction and repair, including timely reconstruction of eyelid for the sake of protecting the eyesight and of alleviating the inflammatory reactions, and the corneal transplantation should be done at the same time to avoid corneal perforation" 02/01/2000 - "Limbal stem cell deficiency was due to chemical burns in 4 patients, history of prior surgery extending to the limbus in 2 patients, chronic limbitis with dystichiasis in one patient and persistent corneal epithelial defect after keratoplasty in one case" 01/01/1997 - "Currently the main indications for LK are "immediate" keratoplasty after chemical burns, and sclerokeratoplasty against recurrent pterygia" Order ALL the reference details at left...
4.	Laser Therapy (Surgery, Laser) 01/01/1989 - "Endoscopic laser therapy of chemical burns of the esophagus (clinico-morphologic studies)]" 01/01/1991 - "Effectiveness of the treatment of chemical burns of the esophagus by local endoscopic laser therapy]" 11/01/1990 - "The local treatment of chemical burns of the esophagus via an endoscope by means of laser therapy and adhesive application]" 03/01/1998 - "This study examined several treatment modalities for partial thickness chemical burns: surgical excision; laser ablation and chemical debridement with Debridase or trypsin-linked to gauze" Order ALL the reference details at left...
5.	Debridement 03/01/1998 - "This study examined several treatment modalities for partial thickness chemical burns: surgical excision; laser ablation and chemical debridement with Debridase or trypsin-linked to gauze" Order ALL the reference details at left...

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