Bunaftine

N-Butyl-N-(2-(diethylamino)ethyl)-1-naphthamide. A proposed antiarrhythmic that prolongs myocardial refractory period and stabilizes cell membranes.

Also Known As:

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Ventricular Tachycardia 01/01/1977 - "[Pharmacological cardioversion of paroxysmal supraventricular and ventricular tachycardias using bunaftine. " 10/01/1976 - "Suppression of aconitine-induced ventricular tachycardia in the dog with various doses of Bunaftine was attempted. " 10/01/1976 - "[Effect of Bunaftine on the ventricular tachycardia due to aconitine in the dog]."
2.	Heart Diseases (Heart Disease) 12/01/1975 - "[Clinical use of bunaftine in the therapy of arrhythmia in patients with decompensated heart disease]." 05/01/1983 - "The effects of intravenous administration of several quinidine-like antiarrhythmic drugs (bunaftine, monochloroacetyl ajmaline, lidocaine, mexiletine, disopyramide, aprindine, diphenylhydantoin, procainamide) on left ventricular performance, evaluated by systolic time intervals (STI), were studied in 100 patients with atherosclerotic heart disease. "
3.	Premature Cardiac Complexes (Extrasystoles) 01/01/1976 - "Extrasystoles increased when Bunaphtine levels diminished. " 01/01/1976 - "To 5 patients showing the appearance or the increase of extrasystole, both ventricular and supraventricular, during ergometric test on the bicycle ergometer, bunaphtine was administered by the following method: a first dose of 0.5 mg/kg was injected endovenously in 2 minutes followed by a constant endovenous infusion at the speed of 2.5 mg/min, throughout the exercise. "
4.	Cardiac Arrhythmias (Arrythmia) 10/01/1974 - "[Use of bunaftine in the therapy of cardiac arrhythmias]." 12/01/1975 - "[Clinical use of bunaftine in the therapy of arrhythmia in patients with decompensated heart disease]."
5.	Sexually Transmitted Diseases (Sexually Transmitted Disease) 05/01/1983 - "The effects of intravenous administration of several quinidine-like antiarrhythmic drugs (bunaftine, monochloroacetyl ajmaline, lidocaine, mexiletine, disopyramide, aprindine, diphenylhydantoin, procainamide) on left ventricular performance, evaluated by systolic time intervals (STI), were studied in 100 patients with atherosclerotic heart disease. "

Related Drugs and Biologics

1.	Anti-Arrhythmia Agents
2.	Quinidine (Chinidin)
3.	Procainamide (Procan)
4.	Phenytoin (Dilantin)
5.	Mexiletine (Mexitil)
6.	Lidocaine (Xylocaine)
7.	Disopyramide (Norpace)
8.	Aprindine
9.	Ajmaline (Wolfina)
10.	Aconitine

Related Therapies and Procedures

1.	Therapeutics
2.	Intravenous Administration
3.	Electric Countershock (Cardioversion)