Bulimia (Binge Eating)

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617 relevant articles (65 outcomes, 100 trials/studies) found for this Disease

Description: Eating an excess amount of food in a short period of time, as seen in the disorder of BULIMIA NERVOSA. It is caused by an abnormal craving for food, or insatiable hunger also known as "ox hunger".

Also Known As:

Binge Eating; Bulimias; Eating, Binge

Relationship Network

Disease Context: Research Results

Signs and Symptoms Pathological Conditions

Signs and Symptoms

Digestive Signs and Symptoms

Hyperphagia: 1316

Bulimia: 617

Related Diseases

1.	Vomiting
2.	Bulimia Nervosa (Binge Eating Disorder)
3.	Weight Loss (Weight Reduction)
4.	Bulimia (Binge Eating)
5.	Obesity

Experts

1.	Masheb, Robin M: 4 articles (11/2007 - 05/2005)
2.	Grilo, Carlos M: 4 articles (11/2007 - 05/2005)
3.	Remschmidt, H: 3 articles (01/2007 - 01/2003)
4.	Hebebrand, J: 3 articles (01/2007 - 01/2003)
5.	Burke-Martindale, Carolyn H: 3 articles (12/2006 - 05/2005)
6.	Rothschild, Bruce S: 3 articles (12/2006 - 05/2005)
7.	Monteleone, Palmiero: 3 articles (10/2006 - 12/2003)
8.	Maj, Mario: 3 articles (10/2006 - 12/2003)
9.	Heinzel-Gutenbrunner, M: 2 articles (01/2007 - 08/2004)
10.	Theisen, F M: 2 articles (01/2007 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bulimia:

1.	Fluoxetine (Prozac)FDA LinkGeneric 03/01/1991 - "The most effective medication for bulimia reported to date is fluoxetine hydrochloride (Prozac)" 11/01/2002 - "RESULTS: Compared with placebo-treated subjects, subjects receiving fluoxetine (mean +/- SD endpoint dose = 71.3 +/- 11.4 mg/day) had a significantly greater reduction in frequency of binge eating (p =.033), body mass index (p <.0001), weight (p =.001), and severity of illness (p =.032) and a marginally significant reduction in HAM-D scores (p =.061)" 01/01/2006 - "AIM: This 12-week open label study was performed to assess the efficacy of buspirone-5-HT1A receptor agonist in the treatment of bulimia, and to compare it with the efficacy of fluoxetine --the standard treatment of BN" 01/01/1999 - "METHOD: Two parallel, multicenter, double-blind, randomized, placebo-controlled fluoxetine clinical trials were retrospectively analyzed to determine the effect of comorbid depression on bulimia treatment response" 05/01/2007 - "Fluoxetine (60 mg/day) decreases the core symptoms of binge eating and purging and associated psychological features in the short term" Order ALL the reference details at left...
2.	Antidepressive Agents (Antidepressants)IBA 04/01/2008 - "Data from the meta-analysis revealed that binge-eating remission rates were higher in patients receiving antidepressants when compared with placebo" 07/01/1986 - "More than 30 reports, including 9 placebo-controlled, double-blind studies, have assessed the efficacy of various medications, mostly antidepressants, for the treatment of bulimia" 05/01/2001 - "Antidepressants are also effective in reducing binge eating, though less so than psychotherapy" 01/01/1984 - "In a retrospective study, 22 patients with bulimia were treated with at least one therapeutic trial of antidepressants" 05/01/2005 - "However, medication management of bulimia with antidepressants has demonstrated only partial resolution of bulimic symptoms" Order ALL the reference details at left...
3.	topiramate (Topamax)FDA Link 06/01/2004 - "Topiramate is an anticonvulsive drug with proven good results in controlling binge eating episodes" 12/01/2003 - "The EAT showed significant improvement in the topiramate group compared with the placebo group for the bulimia/food preoccupation (p =.019) and dieting (p =.031) subscales and the total score (p =.022)" 02/01/2003 - "RESULTS: Compared with placebo, topiramate was associated with a significantly greater rate of reduction in binge frequency, binge day frequency, body mass index, weight, and scores on the Clinical Global Impression severity scale and the Yale-Brown Obsessive Compulsive Scale (modified for binge eating)" 05/01/2007 - "Topiramate induced binge eating remission in 58% of patients (placebo, 29%; p < .001)" 05/01/2007 - "Topiramate reduced binge eating days/week (-3.5 +/- 1.9 vs. -2.5 +/- 2.1), binge episodes/week (-5.0 +/- 4.3 vs. -3.4 +/- 3.8), weight (-4.5 +/- 5.1 kg vs. .2 +/- 3.2 kg), and BMI (-1.6 +/- 1.8 kg/m2 vs. .1 +/- 1.2 kg/m2) compared with placebo (p < .001)" Order ALL the reference details at left...
4.	Serotonin (5 Hydroxytryptamine)IBA 10/01/2003 - "Furthermore, there seems to be a link between improved 5-HT transporter binding and reduced binge eating." 01/01/2007 - "Previous studies support the existence of a bulimia-related endophenotype as well as disturbances in serotonin (5-HT) transmission" 06/01/2004 - "In conclusion, this study extends research suggesting that altered 5-HT neuronal system activity persists after recovery from bulimia-type AN, particularly in subgenual cingulate regions" 05/01/2001 - "The results tentatively suggest that 5-HT transporter binding is decreased in binge-eating women." 05/01/2001 - "RESULTS: Obese binge-eating women showed significantly decreased 5-HT transporter binding in the mid-brain compared with obese controls (2.1 +/- 0.5 versus 2.9 +/- 0.5, respectively)" Order ALL the reference details at left...
5.	Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/01/2005 - "In previous studies, selective serotonin reuptake inhibitors have demonstrated efficacy in reducing the frequency of binge eating and addressing comorbid psychiatric disorders, but they have not shown the ability to promote weight loss" 04/01/2008 - "Regarding binge eating disorder (BED), adult literature shows positive short-term effects on binge eating for both pharmacological (especially selective serotonin reuptake inhibitors) and behavioural interventions, but unclear effects on weight" 07/01/2002 - "In depression as well as in bulimia, selective serotonin reuptake inhibitors significantly decreased the beta-CIT binding potential, however, no significant dose relationship has been obtained in depression" 04/15/2004 - "BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are the first choice for the pharmacologic treatment of bulimia nervosa, but there are no published data on the putative altered serotonin (5-HT) receptor characteristics in patients with bulimia" 01/01/1990 - "Some serotonin uptake inhibitors are finding therapeutic uses in mental depression and other psychiatric disorders and in treating obesity and bulimia; other therapeutic applications continue to be evaluated." Order ALL the reference details at left...
6.	sibutramine (Meridia)FDA Link 11/01/2003 - "Sibutramine was also associated with a significantly greater rate of reduction in Binge Eating Scale (t202 = 3.64; P<.001) and Beck Depression Inventory (t201 = 3.72; P<.001) scores" 05/01/2003 - "There was a significant difference in the number of kilocalories consumed between the sibutramine and placebo conditions, with a significant reduction of intake during binge-eating episodes on sibutramine" 01/01/2008 - "CONCLUSIONS: This trial demonstrated the efficacy of sibutramine in reducing binge eating, weight, and associated psychopathology." 05/01/2003 - "OBJECTIVE: The purpose of this study was to evaluate the effects of sibutramine vs. placebo on binge-eating behavior, hunger, and satiety in patients who had problems with binge eating" 05/01/2003 - "DISCUSSION: Sibutramine suppresses intake during binge-eating episodes" Order ALL the reference details at left...
7.	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 10/01/1985 - "Bulimia and monoamine oxidase inhibitors: a predictor study." 05/01/1984 - "An open trial of MAO inhibitors in bulimia." 12/19/1994 - "Adverse effects, including potentially fatal drug and food interactions, limit the use of the monoamine oxidase inhibitors (MAOIs); however, these agents have a role in the treatment of depression with comorbid anxiety, refractory depression, atypical depression, and bulimia" 11/01/1989 - "Monoamine oxidase inhibitors are commonly prescribed to treat bulimia" 12/01/1982 - "Treatment of bulimia with monoamine oxidase inhibitors." Order ALL the reference details at left...
8.	BESIBA 09/01/2007 - "The main outcome measure was weight change, and secondary outcome measures were binge frequencies, binge remission, Binge Eating Scale (BES) scores, and Beck Depression Inventory (BDI) scores" 03/01/1986 - "This study reports a survey of 202 adolescents, aged 12-18 yr, seen in the Diabetes Clinic, Children's Hospital of Pittsburgh, who were asked to complete the Binge Eating Scale (BES) and the EAT-26 questionnaire" 03/01/2008 - "The Binge Eating Scale (BES) was answered by 128 children and adolescents (10.77+/-2.04 years, BMI 29.15+/-4.98 kg/m2, BMI Z score 2.28+/-0.46, 53.91% pubescent), who were classified into two subgroups--binge eaters (score greater than or equal to 18 points) and non-binge eaters (score lower than 18 points)" 02/27/2008 - "Subjects were divided into four groups based on scores on the Binge Eating Scale (BES) and changes in perceived stress: Binge eaters/low stress reactivity (n=12), binge eaters/high stress reactivity (n=10), non-binge eaters/low stress reactivity (n=6), non-binge eaters/high stress reactivity (n=9)" 02/01/2008 - "Outcomes were changes in weight and in the Three Factor Eating Questionnaire (TFEQ) and Binge Eating Scale (BES) between screening and 17 and 33 months after randomization" Order ALL the reference details at left...
9.	Phenelzine (Nardil)FDA Link 01/01/1987 - "A controlled trial of phenelzine in bulimia." 01/01/1985 - "Thirty normal weight women with bulimia completed a double-blind, placebo-controlled trial of phenelzine sulfate" 01/01/1985 - "A double-blind trial of phenelzine in bulimia." 06/01/1991 - "While medical problems related to the bulimia were few, treatment with phenelzine was associated with three reports of serious hypertensive episodes, one of which led to death" 05/01/1988 - "Phenelzine vs placebo in 50 patients with bulimia." Order ALL the reference details at left...
10.	Sertraline (Zoloft)FDA LinkGeneric 07/01/2004 - "At the end of the observation period, the group treated with sertraline had a statistically significant reduction in the number of binge eating crises and purging compared with the group who received placebo" 07/01/2004 - "This study confirms that sertraline is well tolerated and effective in reducing binge-eating crises and purging in patients with BN." 05/01/2001 - "We report five cases of underweight women with binge eating/purging-type eating disorders who gained weight and had reduced core eating disorder behaviors in response to sertraline." 05/01/2001 - "Sertraline in underweight binge eating/purging-type eating disorders: five case reports." 04/01/2006 - "The present open study assesses the efficacy of sertraline over a period of 24 weeks in obese persons with binge eating behaviour (with or without the full criteria for BED) confirmed by high scores on the Binge Eating Scale (BES)" Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 07/01/2002 - "We examined the results of controlled clinical trials of pharmacotherapies for bulimia published from 1980 to 1999" 02/01/1989 - "The authors review clinical data, family studies, pharmacotherapy, and the neurobiology of bulimia and discuss the nature of the relationship between depression and bulimia." 07/01/2002 - "We found that pharmacotherapy for bulimia yields a moderate initial effect" 09/01/1987 - "Antidepressant drug therapy for bulimia: current status revisited." 07/01/1986 - "Antidepressant drug therapy for bulimia: current status." Order ALL the reference details at left...
2.	Aftercare (After-Treatment) 04/01/2008 - "Participants with lower baseline depression scores were more likely to have partial remission (no longer meeting study entry criteria) after treatment (OR 0.93; p <.01), whereas those with fewer binge-eating/purging episodes at baseline were more likely to have partial remission at follow-up (OR 0.98; p <.05)" 03/01/2007 - "Binge eating, general psychopathology, and body mass index (BMI) were assessed before, during, and after treatment, and at 12-month follow-up" 01/01/2006 - "Furthermore, depressive symptomatology may increase the patient's vulnerability to binge eating as well as to relapse after treatment" 05/01/2005 - "RESULTS: All 6 patients described reported complete abstinence from binge eating and purging after treatment with psychostimulants, and none of the patients discontinued taking the medication because of side effects" 12/01/1999 - "Reductions in binge eating, purging, and food restriction after treatment did not result in significant changes in BMI" Order ALL the reference details at left...
3.	Bariatric Surgery 04/01/2006 - "This study compared two self-report methods for assessing binge eating in severely obese bariatric surgery candidates" 06/01/2005 - "This study examined the characteristics of African American women seeking bariatric surgery, and ethnic differences in BED rates and correlates of binge eating" 05/01/2007 - "OBJECTIVE: This article reviews the status of the literature addressing clinically significant binge eating in the bariatric surgery patient" 05/01/2007 - "Binge eating in the bariatric surgery population: a review of the literature." 12/01/2006 - "CONCLUSION: Binge eating is common in extremely obese bariatric surgery candidates and is associated with heightened eating and psychological problems" Order ALL the reference details at left...
4.	Caloric Restriction 07/24/2007 - "Using rats, we found that footshock stress and a history of caloric restriction (S+R), combine synergistically to induce binge eating" 10/01/2005 - "The authors developed an animal model of binge eating where history of caloric restriction with footshock stress (R + S) causes rats to consume twice the normal amount of palatable food" 09/01/2003 - "We developed an animal model of binge eating in sated rats that is evoked by stress, but only in rats with a history of caloric restriction and only if highly palatable food (HPF) is available after stress" 09/01/2002 - "We hypothesized that caloric restriction and stress interact in a unique manner to promote binge eating" 09/01/2002 - "A new animal model of binge eating: key synergistic role of past caloric restriction and stress." Order ALL the reference details at left...
5.	Phototherapy (Light Therapy) 02/28/1996 - "No effect of light therapy was found on the frequency, size, or content of binge-eating episodes" 12/01/1989 - "Light therapy for seasonal bulimia." 03/01/1996 - "Actually possible new indications for phototherapy are being explored: bright light for non seasonal depression has been tested with features with SAD; effectiveness in bulimia has been suggested and recently sleep disorders in psychogeriatric patients have been improved" 05/01/1994 - "To assess the effectiveness of light therapy for treatment of bulimia nervosa, the authors conducted a study of light therapy during winter comparing an active (bright white light) condition to a control (dim red light) condition in bulimic patients who were not selected for a seasonal pattern of bulimia" 11/01/1993 - "Seasonal bulimia treated with fluoxetine and phototherapy." Order ALL the reference details at left...

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