Bufotenin (Mappin)

A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.

Also Known As:

Networked: 26 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Pimenta, Daniel C: 4 articles (01/2020 - 01/2014)
2.	Vigerelli, Hugo: 4 articles (01/2020 - 01/2014)
3.	Jared, Carlos: 3 articles (01/2018 - 01/2014)
4.	Sciani, Juliana Mozer: 3 articles (01/2018 - 01/2014)
5.	Antoniazzi, Marta Maria: 2 articles (01/2015 - 01/2014)
6.	da Silva, Andréa de Cássia Rodrigues: 2 articles (01/2015 - 01/2014)
7.	Boland, Laura: 1 article (01/2022)
8.	Borkhoff, Cornelia M: 1 article (01/2022)
9.	Forner, David: 1 article (01/2022)
10.	Hong, Paul: 1 article (01/2022)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 07/01/1970 - "Studies on urinary elimination of bufotenine-like substances in schizophrenia." 01/01/2010 - "Urine bufotenine levels were significantly higher in ASD subjects (3.30 +/- 0.49 microg/L, p<0.05) and patients with schizophrenia (4.39 +/- 0.43 microg/L, p<0.001) compared with controls (1.53 +/- 0.30 microg/L). " 01/01/2010 - "Urine bufotenine levels were measured using a high-performance liquid chromatography-mass spectrometry (HPLC-MS) assay in young adults with severe ASD (n=15), patients with schizophrenia (n=15), and healthy control subjects (n=18). " 08/01/1969 - "Influence of triperidol on the urinary elimination of bufotenin in schizophrenia." 06/14/1962 - "[Schizophrenia and bufotenin]."
2.	Mental Disorders (Mental Disorder) 01/01/2010 - "Previous studies have suggested that the endogeneous psychotomimetic molecule bufotenine (N-N-dimethyl-5-idroxytryptamine) may play a role in the pathogenesis of severe mental disorders. " 11/27/1995 - "Thus, the presence and levels of bufotenine might be useful and important markers of some psychiatric disorders." 11/27/1995 - "Bufotenine reconsidered as a diagnostic indicator of psychiatric disorders." 03/01/1978 - "[Urinary excretion of bufotenin, N,N-dimethyltryptamine and 3,4-dimethoxyphenylethylamine and the clinical picture of mental disorders]." 11/27/1995 - "We have analyzed products of the serotonin-degradative pathway, in which both N-methylserotonin and bufotenine are formed in urine specimens of products with psychiatric disorders by three-dimensional HPLC with electrochemical detection. "
3.	Psychotic Disorders (Schizoaffective Disorder) 11/01/2018 - "Previous studies have suggested that the endogenous psychotomimetic molecules bufotenine (BT) and dimethyltryptamine (DMT) may play a role in the pathogenesis of psychotic disorders. " 01/01/1970 - "[N,N-dimethyltryptamine and bufotenin in the urine of patients with chronic and acute schizophrenic psychoses]."
4.	Inflammation (Inflammations) 08/01/2021 - "Bufotenine, as a natural component from toad venom, showed great potential for development as a novel anti-inflammation and analgesia agent. " 08/01/2021 - "This study aimed to investigate the therapeutic effects of bufotenine against inflammation and pain on animal models with a focus on lipid metabolism. " 10/28/2019 - "LPS induced zebrafish was applicated as an in vivo inflammation model to clarify the structure-activity relationship of 4 major IAAs (N-methyl serotonin, bufotenine, dehydrobufotenine and bufothionine) from toad skin. "
5.	Pain (Aches) 08/01/2021 - "This study aimed to investigate the therapeutic effects of bufotenine against inflammation and pain on animal models with a focus on lipid metabolism. "

Related Drugs and Biologics

1.	N,N-Dimethyltryptamine (Dimethyltryptamine)
2.	Therapeutic Uses
3.	Formaldehyde (Formol)
4.	Serotonin (5 Hydroxytryptamine)
5.	Bufotenin (Mappin)
6.	5-Methoxytryptamine (5 Methoxytryptamine)
7.	Methoxydimethyltryptamines (Methoxydimethyltryptamine)
8.	tryptamine
9.	Hallucinogens (Psychedelics)
10.	Controlled Substances

Related Therapies and Procedures

1.	Tourniquets
2.	Analgesia
3.	Aftercare (After-Treatment)