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Bruxism

A disorder characterized by grinding and clenching of the teeth.
Also Known As:
Disorder, Teeth Grinding; Grinding Disorder, Teeth; Teeth Grinding Disorders; Bruxomania; Teeth Grinding Disorder
Networked: 758 relevant articles (66 outcomes, 143 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Temporomandibular Joint Disorders (Temporomandibular Joint Disorder)
2. Pain (Aches)
3. Myalgia
4. Torticollis (Wryneck)
5. Sleep Bruxism

Experts

1. Lobbezoo, F: 14 articles (05/2019 - 07/2000)
2. Manfredini, Daniele: 11 articles (01/2022 - 04/2008)
3. Lobbezoo, Frank: 9 articles (02/2020 - 01/2005)
4. Naeije, M: 9 articles (07/2008 - 07/2000)
5. Kisch, Jenö: 7 articles (07/2020 - 07/2017)
6. Bussadori, Sandra Kalil: 6 articles (01/2020 - 10/2013)
7. Albrektsson, Tomas: 6 articles (02/2018 - 10/2015)
8. Chrcanovic, Bruno Ramos: 6 articles (02/2018 - 10/2015)
9. Wennerberg, Ann: 6 articles (02/2018 - 10/2015)
10. Winocur, E: 5 articles (10/2019 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bruxism:
1. Type A Botulinum Toxins (Botox)FDA Link
2. Botulinum Toxins (Botulinum Toxin)IBA
3. incobotulinumtoxinAFDA Link
4. Buspirone (Buspar)FDA LinkGeneric
5. Paroxetine (Paxil)FDA LinkGeneric
6. Dental Implants (Dental Implant)IBA
7. Hydroxyzine (Vistaril)FDA LinkGeneric
8. Levodopa (L Dopa)FDA LinkGeneric
9. Trazodone (Trittico)FDA LinkGeneric
10. Propranolol (Inderal)FDA LinkGeneric
02/01/1997 - "The positive response of iatrogenic bruxism to propranolol implies that propranolol also deserves a trial for the treatment of noniatrogenic nocturnal bruxism."
02/01/1997 - "Bruxism secondary to antipsychotic drug exposure: a positive response to propranolol."
02/01/1997 - "Both complications were relieved after the beta-adrenergic blocker propranolol was added, suggesting the involvement of the adrenergic and serotonergic central nervous systems, besides the dopaminergic system, in the pathogenesis of bruxism. "
10/23/2014 - "Studies evaluating bromocriptine, clonidine, propranolol and levodopa reported our primary outcome of indices of bruxism motor activity.Results"
10/23/2014 - "These were the specific findings for each of the drugs according to specific outcomes: 1. Amitriptyline versus placebo for masseteric electromyography (EMG) activity per minute: standardized mean difference (SMD) -0.28 (95% confidence interval (CI) -0.91 to 0.34; P value = 0.37), 2. bromocriptine versus placebo for bruxism episodes per hour: mean difference (MD) 0.60 (95% CI -2.93 to 4.13), bruxism bursts per hour: MD -2.00 (95% CI -53.47 to 49.47), bruxism bursts per episode: MD 0.50 (95% CI -1.85 to 2.85) or number of episodes with grinding noise: MD 2.40 (95% CI -24.00 to 28.80), 3. clonidine versus placebo for number of bruxism episodes per hour: MD -2.41 (95% CI -4.84 to 0.02), 4. propranolol versus placebo for the number of bruxism episodes per hour: MD 1.16 (95% CI -1.89 to 4.21), 5. L-tryptophan versus placebo for masseteric EMG activity per second: SMD 0.08 (95% CI -0.90 to 1.06) and 6. levodopa versus placebo for bruxism episodes per hour of sleep: MD -1.47 (95% CI -3.64 to 0.70), for bruxism bursts per episode: MD 0.06 (95% CI -2.47 to 2.59).We combined several secondary outcomes (sleep duration, masseteric EMG activity per minute and pain intensity) in a meta-analysis for comparison of amitriptyline with placebo. "

Therapies and Procedures

1. Splints (Splint)
2. Occlusal Splints
3. Bite Force (Occlusal Forces)
4. Injections
5. Therapeutics