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Bruxism

A disorder characterized by grinding and clenching of the teeth.
Also Known As:
Disorder, Teeth Grinding; Disorders, Teeth Grinding; Grinding Disorder, Teeth; Grinding Disorders, Teeth; Teeth Grinding Disorders; Teeth Grinding Disorder
Networked: 353 relevant articles (26 outcomes, 54 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Temporomandibular Joint Disorders (Temporomandibular Joint Disorder)
2. Trismus (Lockjaw)
3. Torticollis (Wryneck)
4. Tremor (Tremors)
5. Wounds and Injuries (Trauma)

Experts

1. Lobbezoo, F: 13 articles (06/2014 - 07/2000)
2. Naeije, M: 8 articles (07/2008 - 07/2000)
3. Manfredini, Daniele: 5 articles (10/2014 - 04/2008)
4. Lobbezoo, Frank: 5 articles (06/2014 - 01/2005)
5. Winocur, E: 4 articles (02/2015 - 01/2000)
6. Kaprio, J: 4 articles (07/2013 - 06/2001)
7. Ommerborn, Michelle A: 4 articles (03/2011 - 01/2005)
8. Guarda-Nardini, Luca: 3 articles (10/2014 - 04/2008)
9. Rintakoski, K: 3 articles (07/2013 - 06/2010)
10. Ahlberg, J: 3 articles (07/2012 - 06/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bruxism:
1. Botulinum Toxins (Botulinum Toxin)IBA
2. Paroxetine (Paxil)FDA LinkGeneric
3. onabotulinumtoxinA (Botox)FDA Link
4. Propranolol (Inderal)FDA LinkGeneric
02/01/1997 - "Bruxism secondary to antipsychotic drug exposure: a positive response to propranolol."
02/01/1997 - "The positive response of iatrogenic bruxism to propranolol implies that propranolol also deserves a trial for the treatment of noniatrogenic nocturnal bruxism."
02/01/1997 - "Both complications were relieved after the beta-adrenergic blocker propranolol was added, suggesting the involvement of the adrenergic and serotonergic central nervous systems, besides the dopaminergic system, in the pathogenesis of bruxism. "
01/01/2014 - "Studies evaluating bromocriptine, clonidine, propranolol and levodopa reported our primary outcome of indices of bruxism motor activity.Results"
01/01/2014 - "These were the specific findings for each of the drugs according to specific outcomes: 1. Amitriptyline versus placebo for masseteric electromyography (EMG) activity per minute: standardized mean difference (SMD) -0.28 (95% confidence interval (CI) -0.91 to 0.34; P value = 0.37), 2. bromocriptine versus placebo for bruxism episodes per hour: mean difference (MD) 0.60 (95% CI -2.93 to 4.13), bruxism bursts per hour: MD -2.00 (95% CI -53.47 to 49.47), bruxism bursts per episode: MD 0.50 (95% CI -1.85 to 2.85) or number of episodes with grinding noise: MD 2.40 (95% CI -24.00 to 28.80), 3. clonidine versus placebo for number of bruxism episodes per hour: MD -2.41 (95% CI -4.84 to 0.02), 4. propranolol versus placebo for the number of bruxism episodes per hour: MD 1.16 (95% CI -1.89 to 4.21), 5. L-tryptophan versus placebo for masseteric EMG activity per second: SMD 0.08 (95% CI -0.90 to 1.06) and 6. levodopa versus placebo for bruxism episodes per hour of sleep: MD -1.47 (95% CI -3.64 to 0.70), for bruxism bursts per episode: MD 0.06 (95% CI -2.47 to 2.59).We combined several secondary outcomes (sleep duration, masseteric EMG activity per minute and pain intensity) in a meta-analysis for comparison of amitriptyline with placebo. "
5. Levodopa (L Dopa)FDA LinkGeneric
01/01/1997 - "L-Dopa resulted in a significant decrease in the average number of bruxism episodes per hour of sleep, as well as in a significant reduction in the average value of the root-mean-square (RMS) electromyography (EMG) level per bruxism burst. "
03/01/2004 - "The bruxism responded favourably to low-dose levodopa-carbidopa therapy. "
01/01/2014 - "Studies evaluating bromocriptine, clonidine, propranolol and levodopa reported our primary outcome of indices of bruxism motor activity.Results"
01/01/2014 - "These were the specific findings for each of the drugs according to specific outcomes: 1. Amitriptyline versus placebo for masseteric electromyography (EMG) activity per minute: standardized mean difference (SMD) -0.28 (95% confidence interval (CI) -0.91 to 0.34; P value = 0.37), 2. bromocriptine versus placebo for bruxism episodes per hour: mean difference (MD) 0.60 (95% CI -2.93 to 4.13), bruxism bursts per hour: MD -2.00 (95% CI -53.47 to 49.47), bruxism bursts per episode: MD 0.50 (95% CI -1.85 to 2.85) or number of episodes with grinding noise: MD 2.40 (95% CI -24.00 to 28.80), 3. clonidine versus placebo for number of bruxism episodes per hour: MD -2.41 (95% CI -4.84 to 0.02), 4. propranolol versus placebo for the number of bruxism episodes per hour: MD 1.16 (95% CI -1.89 to 4.21), 5. L-tryptophan versus placebo for masseteric EMG activity per second: SMD 0.08 (95% CI -0.90 to 1.06) and 6. levodopa versus placebo for bruxism episodes per hour of sleep: MD -1.47 (95% CI -3.64 to 0.70), for bruxism bursts per episode: MD 0.06 (95% CI -2.47 to 2.59).We combined several secondary outcomes (sleep duration, masseteric EMG activity per minute and pain intensity) in a meta-analysis for comparison of amitriptyline with placebo. "
01/01/1979 - "Aggression and bruxism were not equally successfully induced after L-dopa given with a peripheral inhibitor of aromatic amino acid decarboxylase (benserazide) or when L-dopa treatment was modified with the inhibitor of dopamine-beta-hydroxylase (diethyldithiocarbamate) or monoamine oxidase inhibitor (iproniazid). "
6. Hydroxyzine (Vistaril)FDA LinkGeneric
7. Buspirone (Buspar)FDA LinkGeneric
8. venlafaxine (Effexor)FDA LinkGeneric
9. Histamine (Histamine Dihydrochloride)FDA Link
10. Clonazepam (Rivotril)FDA LinkGeneric

Therapies and Procedures

1. Splints
2. Psychology Biofeedback (Biofeedback)
3. Oral Hygiene (Dental Hygiene)
4. Aftercare (After-Treatment)
5. Musculoskeletal Manipulations (Manipulative Therapy)