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Bronchiectasis

Persistent abnormal dilatation of the bronchi.
Also Known As:
Bronchiectases; Bronchiectasis, Cylindrical; Bronchiectasis, Cystic; Bronchiectasis, Saccular; Bronchiectasis, Varicose; Cylindrical Bronchiectases; Cystic Bronchiectases; Saccular Bronchiectases; Varicose Bronchiectases; Cylindrical Bronchiectasis; Cystic Bronchiectasis; Saccular Bronchiectasis; Varicose Bronchiectasis
Networked: 3175 relevant articles (218 outcomes, 398 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Cystic Fibrosis (Mucoviscidosis)
2. Asthma (Bronchial Asthma)
3. Chronic Obstructive Pulmonary Disease (COPD)
4. Diffuse panbronchiolitis
5. Infections

Experts

1. Chalmers, James D: 82 articles (03/2022 - 02/2011)
2. Chang, Anne B: 45 articles (11/2022 - 08/2002)
3. Aliberti, Stefano: 42 articles (11/2022 - 04/2015)
4. De Soyza, Anthony: 34 articles (04/2022 - 12/2012)
5. Blasi, Francesco: 32 articles (03/2022 - 05/2015)
6. Hill, Adam T: 31 articles (11/2022 - 02/2011)
7. Polverino, Eva: 27 articles (01/2022 - 02/2009)
8. Grimwood, Keith: 22 articles (11/2022 - 08/2002)
9. Sibila, Oriol: 21 articles (02/2022 - 10/2015)
10. Johkoh, Takeshi: 21 articles (01/2022 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bronchiectasis:
1. Anti-Bacterial Agents (Antibiotics)IBA
02/01/2003 - "Some patients exhibiting severe multisegmental bilateral bronchiectasis are no longer improved with antibiotic treatment and drainage and, most of the time, operation is contraindicated. "
01/01/2022 - "It is important to weigh the evidence for bacterial suppression against the prevention of antibiotic resistance and further evidence is required on the safety and efficacy of different regimens of intermittently administered antibiotic treatments for people with bronchiectasis. "
01/01/2019 - "Surgical management of non-CF bronchiectasis has no significant effect on BMI z-scores, annual exacerbation frequencies, oral antibiotic requirements and lung function tests; but can lead to significant improvement on height z-scores and decrease need of annual intravenous antibiotic requirements for acute severe exacerbations despite small number of patients in this study."
11/25/2022 - "Nebulised antibiotics and the presence of bronchiectasis were statistically significant predictors of remission (HR: 3.99; 95%CI: 1.12-14.14; p = 0.032, and HR: 0.24; 95%CI: 0.08-0.71; p = 0.010). "
12/01/2015 - "Forced expiratory volume in 1 s improved after physiotherapy, as did alveolar volume after intravenous antibiotics, but LCI did not change significantly.LCI is reproducible in stable bronchiectasis but unlike conventional lung function tests, is unresponsive to two short-term interventions and hence is unlikely to be a useful clinical tool for short-term acute assessment in these patients. "
2. MacrolidesIBA
3. Mannitol (Osmitrol)FDA LinkGeneric
4. PowdersIBA
5. Azithromycin (Zithromax)FDA LinkGeneric
6. Tobramycin (Nebcin)FDA LinkGeneric
7. Ciprofloxacin (Cipro)FDA LinkGeneric
8. Adrenal Cortex Hormones (Corticosteroids)IBA
9. SolutionsIBA
10. AerosolsIBA

Therapies and Procedures

1. Therapeutics
2. Traction
3. Aftercare (After-Treatment)
07/01/2019 - "This study demonstrates patients with bronchiectasis can demonstrate improved HRQoL after treatment at a specialized care center and these improvements are maintained for most patients 2 years after the initial visit."
11/01/2012 - "Furthermore, the scores for extent of bronchiectasis (2.7 ± 1.6), the scores for the bronchial wall thickening of bronchiectasis (1.3 ± 0.4) and the global CT score (6.7 ± 2.5) in the treatment group were significantly improved as compared with those [(4.8 ± 2.0), (1.8 ± 0.5), (9.7 ± 3.6)] in the control group respectively after treatment. "
08/01/2016 - "The score of clinical symptoms for bronchiectasis, forced expiratory volume in one second (FEV1), SNOT-22 score, and Lund-Mackay score were evaluated for all cases before and after treatment, respectively, and then the value changes in the score of clinical symptoms, FEV1, SNOT-22 score, and Lund-Mackay score between both time points were calculated. "
11/01/2012 - "The scores for the extent of bronchiectasis (2.7 ± 1.6), the bronchial wall thickening of bronchiectasis (1.3 ± 0.4) and the global CT score (6.7 ± 2.5) were reduced after treatment as compared to those before treatment [(4.8 ± 2.3), (1.8 ± 0.5), (9.5 ± 3.3)] in the treatment group, (all P < 0.01). "
11/01/2009 - "Among 12 patients with bronchiectasis, there were 4 men and 8 women with the mean age of 47.58 (SD=18.32) yr. The mean increase in the ratios of VC, FVC and FEV₁ to predicted values and also patients FEV₁/FVC after treatment were 15.50% (SD=14.40), 49.83% (SD=8.19) 8.17% (SD=12.07) and 7.17% (SD=12.68), respectively. "
4. Lung Transplantation
5. Postural Drainage