|1.||Shukla, Yogeshwer: 6 articles (04/2015 - 01/2008)|
|2.||Hale, Laura P: 6 articles (12/2010 - 02/2004)|
|3.||Thrall, Roger S: 5 articles (01/2013 - 09/2005)|
|4.||Secor, Eric R: 5 articles (01/2013 - 09/2005)|
|5.||Rosenberg, Lior: 5 articles (02/2012 - 12/2004)|
|6.||Ehteda, Anahid: 4 articles (10/2015 - 01/2013)|
|7.||Pillai, Krishna: 4 articles (02/2014 - 01/2013)|
|8.||Schramm, Craig M: 4 articles (01/2013 - 09/2005)|
|9.||Bhui, Kulpreet: 4 articles (03/2012 - 01/2008)|
|10.||Greer, Paula K: 4 articles (12/2010 - 04/2005)|
12/01/2002 - "We conclude that bromelain may be effective in ameliorating physical symptoms and improving general well-being in otherwise healthy adults suffering from mild knee pain in a dose-dependant manner. "
12/01/2002 - "The current study investigated the effects of bromelain on mild acute knee pain of less than 3 months duration in otherwise healthy adults. "
12/01/2002 - "Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults."
06/01/2014 - "Perioperative bromelain reduces pain and swelling and improves quality of life measures after mandibular third molar surgery: a randomized, double-blind, placebo-controlled clinical trial."
10/18/1958 - "The relief of pain in spasmodic dysmenorrhoea by bromelain."
03/01/2014 - "Although there were no statistically significant differences between the treatment groups, a trend towards less inflammation and improved oral aperture was observed in the group that received Bromelain, compared to the group that received placebo. "
07/01/2008 - "Taken together, these studies demonstrate that bromelain can effectively decrease neutrophil migration to sites of acute inflammation and support the specific removal of the CD128 chemokine receptor as a potential mechanism of action."
01/01/1967 - "Biochemical studies on the resolution of experimental inflammations in animals treated with bromelain."
08/01/2011 - "Bromelain could be a lead compound for the development of new drugs, able to normalize the intestinal motility in inflammation and diabetes."
07/01/2008 - "Intravital microscopy demonstrated that although in vivo bromelain treatment transiently decreased leukocyte rolling, its primary long-term effect was abrogation of firm adhesion of leukocytes to blood vessels at the site of inflammation. "
|3.||Wounds and Injuries (Trauma)
02/01/2015 - "Bromelain has been shown to be effective for removing necrotic tissues and has been found to be effective for treating various wounds, inflammatory conditions, and thrombotic pathologies. "
08/01/2012 - "Bromelain ameliorates the wound microenvironment and improves the healing of firearm wounds."
08/01/2012 - "The purpose of the present study was to investigate the effect of bromelain on the microenvironment of firearm wounds. "
10/01/2013 - "Usage of bromelain as a therapeutic drug for chronic human wounds thus remains a very promising concept for the future."
08/01/2012 - "Sixteen Chinese landrace pigs wounded by high-velocity projectiles were divided randomly into four groups: wound incision (group I), incision + bromelain (group IB), wound excision (group E), and control. "
04/16/1981 - "Whereas after enteral application of bromelain a significant reduction of the edema could be observed, the parenteral application only resulted in a minimal therapeutic effect. "
09/01/2010 - "The obtained results clearly demonstrate the effectiveness of bromelain in treating postoperative edema after third molar surgery."
04/16/1981 - "The edema producing property of a proteolytic enzyme (bromelain), which was parenterally or intraduodenally applied, was investigated in a traumatically induced hindleg edema in rats. "
09/01/2010 - "The aim of the present study is to assess the efficacy of bromelain in controlling the edema and its related pain in the inflamed area after upper third molar exodontia. "
06/01/1965 - "[On the oral therapy of posttraumatic edema and hematomas with the plant proteolytic enzyme bromelain]."
01/01/2013 - "In the present study, we investigated the cytotoxic effects of bromelain in four human cancer cell lines of gastrointestinal origin and the mechanisms involved. "
04/01/2015 - "Several evidences highlight the importance of Bromelain (BL), a proteolytic enzyme, as an anti-tumor agent which however has been limited due to the requirement of high doses at the tumor site. "
01/01/2014 - "Bromelain has novel medicinal qualities including anti-inflammatory, anti-thrombotic, fibrinolytic and anti-cancer functions. "
03/01/2012 - "Since, the inflammatory cascade is well-known to be closely allied to cancer; we studied the effect of bromelain on events/molecules central to it. "
04/28/2010 - "The review will also identify specific new research questions that will need to be addressed in order for a full assessment of bromelain-based anti-cancer therapy."
|3.||Peptide Hydrolases (Proteases)
|6.||Diclofenac (SR 38)
|8.||Interleukin-10 (Interleukin 10)
|4.||Skin Transplantation (Skin Grafting)