Breast Diseases (Breast Disease)

918 relevant articles (31 outcomes, 116 trials/studies) found for this Disease

Description: Pathological processes of the BREAST.

Also Known As:

Breast Disease; Diseases, Breast; Endocrine Breast Diseases; Breast Disease, Endocrine; Breast Diseases, Endocrine; Disease, Breast; Disease, Endocrine Breast; Diseases, Endocrine Breast; Endocrine Breast Disease

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Disease Context: Research Results

Skin and Connective Tissue Diseases

Skin Diseases: 5861

Breast Diseases: 918

Breast Neoplasms: 59104

Mastitis: 1673

Gynecomastia: 810

Fibrocystic Breast Disease: 233

Breast Cyst: 215

Lactation Disorders: 37

Related Diseases

1.	Breast Neoplasms (Breast Cancer)
2.	Ovarian Neoplasms (Ovarian Cancer)
3.	Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases)
4.	Endometrial Neoplasms (Endometrial Cancer)
5.	Ovarian Cysts (Ovarian Cyst)
121 Diseases and 504 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Breast Diseases:

1.	Oral ContraceptivesIBA 07/01/1982 - "Studies have documented the protective effects of oral contraceptives (OCs) against 5 diseases: 1) OCs prevent 50-75% of potential cases of benign breast disease; there is an estimated annual reduction of 235 hospitalized cases for every 100,000 U.S" 08/01/1977 - "In a large study in the Boston area, the risk of benign breast disease for pill users was .4. It appears that women with no history of oral contraceptives have a greater risk of developing benign breast disease" 08/01/1977 - "Since the use of oral contraceptives is very high in young women, existing studies were reviewed to discover the association between oral contraceptives and benign breast disease" 12/01/2007 - "Oral contraceptives and benign breast disease: an update of findings in a large cohort study." 01/01/1995 - "The progestin present in oral contraceptives substantially reduces the risk of benign breast disease" Get all the results and reference details, order at left...
2.	Tamoxifen FDA LinkGeneric 02/19/2003 - "CONCLUSION: Women in this study who received tamoxifen, especially younger women (i.e., <50 years), had a reduced incidence of clinically detected benign breast disease and underwent fewer breast biopsies." 11/01/2006 - "Tamoxifen also reduced the incidence of benign breast disease as well as the number of breast biopsies in the treated women" 02/19/2003 - "RESULTS: Overall, tamoxifen treatment reduced the risk of benign breast disease by 28% (RR = 0.72, 95% confidence interval [CI] = 0.65 to 0.79)" 02/19/2003 - "We examined the effect of tamoxifen treatment on the incidence of benign breast disease and the number of breast biopsies in the same group of women" 04/01/1986 - "Initial thermic breast values recorded by contact thermography in 29 premenopausal patients with benign breast disease were compared to those recorded 4 and 24 hours after a single 20 mg tamoxifen oral administration" Get all the results and reference details, order at left...
3.	HormonesIBA 03/01/2007 - "Physician records for an additional 126 case patients and 90 control participants not reporting hormone therapy but reporting oral contraceptive use or benign breast disease were also obtained" 11/15/2000 - "Reproductive risk factors, benign breast disease, use of postmenopausal hormones, weight, and alcohol intake were evaluated as risk factors" 02/01/1998 - "The importance of hormone receptors in benign breast diseases]" 11/01/1996 - "A statistically significant (p 0.001) difference between hormone users and controls was observed in the incidence of benign breast disease" 01/01/1991 - "Hormone treatment of benign breast diseases]" Get all the results and reference details, order at left...
4.	Danazol (Azol)FDA LinkGeneric 01/01/1995 - "In conclusion, this study confirms that danazol offers very good therapeutic results for the treatment of the frequently persisting benign breast disease." 04/24/1982 - "Controlled trial of the antigonadotropin danazol in painful nodular benign breast disease." 01/01/2002 - "CONCLUSION: The patients with ER positive breast disease responded better to danazol than patients with ER negative breast disease." 08/01/1989 - "Mechanism of action of danazol, personal clinical experiences and guidelines for the treatment of benign breast diseases]" 08/01/1989 - "Danazol therapy in benign breast diseases]" Get all the results and reference details, order at left...
5.	Progestins (Progestagens)IBA 01/01/1995 - "Gestagens and breast diseases]" 11/01/1991 - "Progestins, at least in the high doses used in early orals, protect against benign breast disease" 01/01/1995 - "Most studies suggest that progestins are effective in the treatment of premenstrual syndrome and benign breast disease" 06/11/1983 - "An improved knowledge of the mode of action of individual available progestins results in better management of a wide variety of clinical disorders including, amongst others, endometrial pathology, benign breast diseases, hirsutism and acne." 12/01/1999 - "The benefits of progestins can be obtained in various clinical conditions, including bleeding disorders; benign proliferative diseases (such as benign breast disease, endometrial hyperplasia and endometriosis); contraception; androgenization; and gynecological oncology." Get all the results and reference details, order at left...
6.	AntigensIBA 04/01/1993 - "We performed immunocytochemical staining of benign, in situ, and malignant breast disease to identify antigens related to the presence of the major parenchymal cell types of the normal breast" 04/01/1988 - "The finding of only small foci of weak positivity for D5 antigen in normal and benign breast disease indicated that there are similarities between the expression of D5 antigen and the presence of oestrogen receptor protein in these tissues" 03/01/1986 - "Areas of benign breast disease showed a more varied pattern of antigen expression" 06/01/1983 - "No differences were detected between controls and patients with benign or malignant breast disease in reactivity to T- and MN-antigens" 06/01/1982 - "Cell-mediated immunity to mouse mammary tumor virus antigens by patients with hyperplastic benign breast disease." Get all the results and reference details, order at left...
7.	Progesterone FDA LinkGeneric 01/01/1989 - "The efficacy of topical administration of progesterone in patients with benign breast disease has also been proven" 11/01/1984 - "Earlier studies of the serum concentration of progesterone during the luteal phase in women with benign breast disease have produced conflicting results" 01/01/1999 - "Taken together, these results suggest at least an absence of deleterious effects caused by percutaneous progesterone use in women with benign breast disease." 01/01/1999 - "Percutaneous progesterone topically applied on the breast has been proposed and widely used in the relief of mastalgia and benign breast disease by numerous gynecologists and general practitioners" 12/01/1985 - "Although these volunteers comprised patients with benign and malignant breast disease and normal unaffected women, the relationship between salivary and blood progesterone was similar for all groups" Get all the results and reference details, order at left...
8.	Biological Markers (Surrogate Marker)IBA 05/01/2008 - "These changes may constitute novel biomarkers or reveal novel treatment modalities that could inhibit progression from primary to metastatic breast disease." 09/15/2006 - "Our study provides evidence supporting the potential role of serum MMP2/9 as biomarkers for breast disease classification." 12/01/2000 - "Classification of preinvasive breast disease could be better founded using biologic markers, thereby increasing reproducibility" 05/01/2008 - "Because it is independently related to a personal history of benign or malignant breast disease and to predicted breast cancer risk, it may have value for breast cancer risk stratification and as a surrogate endpoint marker in prevention trials." 08/15/2003 - "An example is given from a study of risk factors for progression of benign breast disease to breast cancer, in which the risk factor is a biological marker measured with poor sensitivity." Get all the results and reference details, order at left...
9.	alpha-Tocopherol FDA Link 05/01/1990 - "We conclude that alpha-tocopherol is not beneficial in the treatment of benign breast disease" 01/01/1983 - "In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day)" 01/01/1985 - "Alpha-tocopherol (vitamin E) has been used to treat patients with benign breast disease" 09/01/1981 - "The results suggest that alpha-tocopherol may serve as an effective agent not only to treat patients with benign breast disease but also to normalize abnormal hormone and lipid levels in subjects at high risk for breast cancer." 09/01/1981 - "Results of this study indicate that alpha-tocopherol therapy may correct an abnormal progesterone/estradiol ratio in patients with mammary dysplasia, with implications on reducing future risk for malignant breast disease." Get all the results and reference details, order at left...
10.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/01/2007 - "METHODS: The tissue expression of VEGF, Flt-1, and Tie-2 were investigated by immunohistochemistry, and plasma levels assessed by enzyme-linked immunosorbent assay in 36 patients with breast cancer and 15 with benign breast disease" 01/01/2003 - "RESULTS: Plasma VEGF levels were higher in malignant than in benign breast disease, and were also high in patients with recurrence or distant metastasis" 01/01/2003 - "We measured plasma VEGF levels, which evaluate the level of tumor-derived VEGF, in various breast diseases" 06/21/1999 - "Our data demonstrate that KDR activation is enhanced in breast cancer in vivo and emphasize the functional role of VEGF and KDR in the development of malignant breast disease." 06/01/2007 - "RESULTS: There was no difference in serum concentrations of VEGF, NO and u-PA between controls and patients with benign breast disease" Get all the results and reference details, order at left...
460 Drugs and Important Bio-Agents and 804 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Contraception (Birth Control) 01/01/1995 - "Our data are in concordance with other epidemiological studies, that showed no influence on breast mitosis and apoptosis and that there was a reduced incidence of benign breast disease; we also believe that it has a beneficial effect and that this method of contraception is the best." 05/01/1982 - "Adequate control for both selection bias and confounding factors influenced by physicians' prescribing practices and the benign breast disease patients' choice of contraception has not been carried out in the majority of studies reported" 06/01/1997 - "Hormonal contraception and benign breast disease" 01/01/1991 - "Oral contraception and benign breast diseases]" 01/01/1991 - "Oral contraception and benign breast diseases: point of view of the epidemiologist]" Get all the results and reference details, order at left...
2.	Modified Radical Mastectomy (Mastectomy, Modified) 02/01/1981 - "Improvements include an increase in case accrual by an average of 100 cases per year; an increase in detection of early (in situ and localized) and advanced disease; an increase in the proportion of patients whose interval from first symptoms to diagnosis was less than one month; a threefold increase in the proportion of patients diagnosed before admission; the increased use of simple or modified radical mastectomy (from 11% to 25%); a reduction in the number of patients whose mastectomy was done by a physician who did five or fewer mastectomies per year; an increase in the number of patients receiving bone, liver, or spleen scans; and an improvement in the quantity and quality of information in hospital charts, such as family history of cancer, history of benign breast disease, and menstrual history" 01/01/1987 - "This study reports data from 412 women prospectively studied over a 1-year period from five collaborating centers: one group had modified radical mastectomy for Stages I and II breast cancer, 145; cholecystectomy for gallbladder disease, 90; biopsy for benign breast disease, 87; and healthy women, 90" Get all the results and reference details, order at left...
3.	Mastectomy (Mammectomy) 01/01/2004 - "METHODS: In this cross-sectional study, all records of pathologic specimens (biopsy or mastectomy) categorized as "breast diseases" from 1996 to 2000 in five teaching hospitals in Tehran were studied" 03/01/2000 - "It is not at all uncommon for surgeons dealing with breast disease to be confronted with the issue of prophylactic mastectomy" 01/01/2000 - "A retrospective technical review of 197 two-stage delayed reconstructions following mastectomy for malignant breast disease in 189 patients." 11/01/1999 - "Bilateral breast disease resulting in bilateral mastectomies over long-term follow-up, as in the case presented here, was reported in 3 of 33 cases." 12/01/1996 - "Among patients with stage I and stage II disease, breast conservation therapy yields survival rates equivalent to those for mastectomy" Get all the results and reference details, order at left...
4.	Lasers (Laser) 12/01/1997 - "The contrast of breast disease in an image produced by a time-domain, near-infrared laser, imaging system was calculated by use of a finite-difference method" 01/01/2008 - "To determine whether molecular profiles can discriminate breast disease by grade, patterns and levels of allelic imbalance (AI) at 26 chromosomal regions frequently altered in breast disease were examined in 185 laser microdissected specimens representing well-differentiated (grade 1; n = 55), moderately-differentiated (grade 2; n = 71), and poorly-differentiated (grade 3; n = 59) stage I-IV breast tumors" 11/01/2004 - "We used laser-assisted microdissection of paraffin-embedded breast tissues from 30 patients with breast disease and a panel of 52 microsatellite markers defining 26 chromosomal regions to characterize genomic patterns of allelic imbalance (AI) in disease-free tissue adjacent to sites of breast disease and to define genomic regions that may contain genes associated with early carcinogenic processes" Get all the results and reference details, order at left...
5.	Fat-Restricted Diet (Diet, Fat Restricted) 03/01/1994 - "Between 1990 and 1993, we conducted a prospective cohort study to find out the efficacy of a low fat diet (less than 15% fat-derived calories) in the treatment of benign breast disease in patients who had been symptomatic for 6 months or more" 03/01/1994 - "Efficacy of low fat diet in the treatment of benign breast disease." 03/01/1994 - "A low fat diet improves the symptoms as well as the lipid profile in patients with benign breast disease." Get all the results and reference details, order at left...
44 Therapies and Procedures and 165 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

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