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Brain Edema (Cerebral Edema)

Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Also Known As:
Cerebral Edema; Edema, Cerebral; Brain Swelling; Cerebral Edema, Cytotoxic; Cerebral Edema, Vasogenic; Cytotoxic Cerebral Edema; Vasogenic Brain Edema; Brain Edema, Cytotoxic; Brain Edema, Vasogenic; Brain Swellings; Cerebral Edemas, Vasogenic; Edema, Brain; Edema, Cytotoxic Brain; Edema, Cytotoxic Cerebral; Edema, Intracranial; Edema, Vasogenic Brain; Edema, Vasogenic Cerebral; Swelling, Brain; Cytotoxic Brain Edema; Intracranial Edema; Vasogenic Cerebral Edema
Networked: 6832 relevant articles (670 outcomes, 794 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Infarction (Infarctions)
2. Ischemia
3. Cerebral Infarction
4. Stroke (Strokes)
5. Brain Ischemia (Cerebral Ischemia)

Experts

1. Zhang, John H: 114 articles (01/2022 - 08/2004)
2. Tang, Jiping: 80 articles (01/2022 - 10/2004)
3. Xi, Guohua: 54 articles (01/2021 - 02/2002)
4. Keep, Richard F: 52 articles (01/2021 - 02/2002)
5. Hua, Ya: 49 articles (01/2021 - 02/2002)
6. Simard, J Marc: 34 articles (01/2022 - 04/2006)
7. Keep, R F: 34 articles (01/2010 - 01/2000)
8. Chen, Gang: 33 articles (03/2022 - 10/2007)
9. Butterworth, Roger F: 31 articles (12/2016 - 07/2002)
10. Hua, Y: 31 articles (01/2010 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Brain Edema:
1. Mannitol (Osmitrol)FDA LinkGeneric
2. Proteins (Proteins, Gene)FDA Link
3. Evans Blue (Blue, Evans)FDA Link
4. Dexamethasone (Maxidex)FDA LinkGeneric
5. CytokinesIBA
6. SteroidsIBA
7. Caspase 3 (Caspase-3)IBA
8. Adrenal Cortex Hormones (Corticosteroids)IBA
9. Interleukin-6 (Interleukin 6)IBA
10. Bevacizumab (Avastin)FDA Link

Therapies and Procedures

1. Therapeutics
2. Cardiopulmonary Resuscitation (CPR)
3. Decompressive Craniectomy
4. Craniotomy
5. Transplantation