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Brain Edema (Cerebral Edema)

Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
Also Known As:
Cerebral Edema; Edema, Cerebral; Brain Swelling; Cerebral Edema, Cytotoxic; Cerebral Edema, Vasogenic; Cytotoxic Cerebral Edema; Vasogenic Brain Edema; Brain Edema, Cytotoxic; Brain Edema, Vasogenic; Brain Swellings; Cerebral Edemas, Vasogenic; Edema, Brain; Edema, Cytotoxic Brain; Edema, Cytotoxic Cerebral; Edema, Intracranial; Edema, Vasogenic Brain; Edema, Vasogenic Cerebral; Swelling, Brain; Cytotoxic Brain Edema; Intracranial Edema; Vasogenic Cerebral Edema
Networked: 3983 relevant articles (305 outcomes, 508 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Stroke (Strokes)
2. Ischemia
3. Brain Ischemia (Cerebral Ischemia)
4. Brain Injuries (Brain Injury)
5. Edema

Experts

1. Zhang, John H: 74 articles (01/2016 - 08/2004)
2. Tang, Jiping: 50 articles (01/2016 - 10/2004)
3. Xi, Guohua: 41 articles (01/2016 - 02/2002)
4. Keep, Richard F: 39 articles (01/2016 - 02/2002)
5. Hua, Ya: 37 articles (01/2016 - 02/2002)
6. Keep, R F: 34 articles (01/2010 - 01/2000)
7. Hua, Y: 31 articles (01/2010 - 01/2000)
8. Butterworth, Roger F: 28 articles (03/2015 - 07/2002)
9. Xi, G: 28 articles (01/2010 - 01/2000)
10. Hoff, J T: 24 articles (01/2008 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Brain Edema:
1. Mannitol (Osmitrol)FDA LinkGeneric
2. Dexamethasone (Maxidex)FDA LinkGeneric
3. OxygenIBA
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
5. Evans Blue (Blue, Evans)FDA Link
6. MethylprednisoloneFDA LinkGeneric
7. Adrenal Cortex Hormones (Corticosteroids)IBA
8. SteroidsIBA
9. Caspase 3 (Caspase-3)IBA
10. Glycerol (Glycerine)FDA LinkGeneric

Therapies and Procedures

1. Decompressive Craniectomy
2. Ligation
3. Craniotomy
4. Intravenous Infusions
5. Transplantation (Transplant Recipients)