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Brain Death (Brain Dead)

A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)
Also Known As:
Brain Dead; Irreversible Coma; Brain Deads; Coma, Irreversible; Death, Brain; Coma Depasse
Networked: 3647 relevant articles (115 outcomes, 379 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Death (Near-Death Experience)
2. Inflammation (Inflammations)
3. Apnea
4. Primary Graft Dysfunction
5. Ischemia

Experts

1. Ploeg, Rutger J: 32 articles (01/2022 - 10/2003)
2. Leuvenink, Henri G D: 27 articles (09/2021 - 11/2003)
3. Schnuelle, Peter: 18 articles (01/2019 - 05/2004)
4. Yard, Benito A: 17 articles (11/2018 - 05/2004)
5. Date, Hiroshi: 13 articles (04/2022 - 03/2002)
6. Cypel, Marcelo: 13 articles (01/2022 - 10/2009)
7. Pratschke, Johann: 13 articles (01/2022 - 11/2001)
8. Cooper, David K C: 13 articles (11/2021 - 08/2005)
9. Seelen, Marc A: 13 articles (01/2021 - 11/2008)
10. Muiesan, Paolo: 13 articles (10/2020 - 09/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Brain Death:
1. dicarboxydine (DCD)IBA
2. Acetylcysteine (Siran)FDA LinkGeneric
3. Dopamine (Intropin)FDA LinkGeneric
4. Norepinephrine (Noradrenaline)FDA LinkGeneric
5. CytokinesIBA
6. Oxygen (Dioxygen)IBA
7. Proteins (Proteins, Gene)FDA Link
8. Triiodothyronine (Liothyronine)FDA LinkGeneric
9. SolutionsIBA
10. Hormones (Hormone)IBA

Therapies and Procedures

1. Transplantation
2. Liver Transplantation
3. Therapeutics
4. Heart Transplantation (Grafting, Heart)
5. Lung Transplantation