Bradycardia

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6475 relevant articles (222 outcomes, 302 trials/studies) found for this Disease

Description: Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK.

Also Known As:

Bradyarrhythmias; Bradycardias; Bradyarrhythmia

Relationship Network

Disease Context: Research Results

Cardiovascular Diseases: 18449

Heart Diseases: 12331

Cardiac Arrhythmias: 8618

Bradycardia: 6475

Signs and Symptoms Pathological Conditions

Pathologic Processes: 2205

Cardiac Arrhythmias: 8618

Bradycardia: 6475

Related Diseases

1.	Hypotension (Low Blood Pressure)
2.	Tachycardia (Tachyarrhythmias)
3.	Anoxia (Hypoxia)
4.	Hypertension (High Blood Pressure)
5.	Heart Failure
461 Diseases and 3468 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Caffrey, J L: 4 articles (09/2003 - 02/2001)
2.	Farias, M: 4 articles (09/2003 - 02/2001)
3.	Tobias, Joseph D: 3 articles (01/2006 - 04/2003)
4.	Kapusta, Daniel R: 2 articles (09/2008 - 07/2007)
5.	Burmeister, Melissa A: 2 articles (09/2008 - 07/2007)
6.	Kanoo, Sadhana: 2 articles (04/2008 - 09/2006)
7.	Deshpande, Shripad B: 2 articles (04/2008 - 09/2006)
8.	Alex, Anitha B: 2 articles (04/2008 - 09/2006)
9.	Charuluxananan, Somrat: 2 articles (02/2008 - 09/2006)
10.	Kyokong, Oranuch: 2 articles (02/2008 - 09/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bradycardia:

1.	Atropine (Hyoscyamine)FDA LinkGeneric 12/01/1987 - "These data evidence that the atropine test is not very helpful in discriminating between an organic and an autonomic involvement of sinus automaticity in patients with sinus bradycardia." 01/01/1988 - "In both cases atropine was effective for a short time in the control of bradycardia." 01/01/2001 - "The protective effects of atropine against bradycardia lasted 50 minutes" 05/01/1992 - "Atropine given i.v. almost totally eliminated the bradycardia and partially prevented the hypotensive responses to intra-HF DA1-8" 09/01/1992 - "Atropine reversed the bradycardia and improved measured cardiovascular parameters." Get all the results and reference details, order at left...
2.	Propranolol (Inderal)FDA LinkGeneric 10/01/1980 - "In this study we compared the dose needed to lower blood pressure upon i.c.v. infusion with the dose of 5 mg/kg x day dl-propranolol, which we reported earlier to induce a long lasting bradycardia and antihypertensive effect when infused s.c" 10/20/1978 - "Four patients had to be excluded from the study because they developed either marked bradycardia or anxiety states or paraesthesias after propranolol (3 x 40 mg/d)" 06/19/1976 - "Propranolol had been stopped 1 to 14 days before each acute event because of angiographic study (seven patients), increasing symptoms (three), acute coronary insufficiency (one), asymptomatic bradycardia (one), elective surgery (one) and unknown reasons (two)" 03/01/2006 - "Attenuation of propranolol-induced bradycardia observed in the lipid emulsion group approached statistical significance (0% vs. 10.3%, p=0.06)" 03/01/1999 - "Side effects of propranolol included symptomatic bradycardia requiring reduction of dose in one of 15 patients" Get all the results and reference details, order at left...
3.	OxygenIBA 01/01/1994 - "Bradycardia has been shown to be beneficial for the normal and ischaemic heart because it improves diastolic perfusion and oxygen supply demand balance" 03/01/1986 - "In contrast, in a dabbling duck (Anas platyrhynchos) bradycardia in short dives was eliminated by breathing oxygen before a dive" 03/01/1986 - "Bradycardia was unaffected by breathing oxygen before a dive, but was virtually eliminated by local anaesthesia of the narial region" 01/01/2006 - "BACKGROUND: Physiological monitoring studies indicate that some preterm infants experience episodes of oxygen desaturation, apnoea, or bradycardia when seated in standard car safety seats" 11/01/2005 - "Physiological monitoring studies have shown that some preterm infants who are otherwise ready for hospital discharge experience episodes of oxygen desaturation, apnoea, or bradycardia when seated in standard car safety seats" Get all the results and reference details, order at left...
4.	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 04/30/1998 - "The magnitude of the baroreceptor reflex mediated bradycardia, induced by a phenylephrine induced pressor response, was significantly greater in NK1 knockout mice (P < 0.001) compared to heterozygous and wild-type animals" 11/03/1992 - "Comparable increments in blood pressure evoked by systemic AVP, as opposed to phenylephrine, were associated with significantly greater reflex bradycardia" 02/01/1988 - "Bradycardia elicited by phenylephrine-induced increases in pressure was significantly greater after NTS injection of [Sar1, Thr8]Ang II. The slope of the pulse interval-arterial pressure relationship was 0.60 +/- 0.09 ms/mm Hg after injection, as compared with 0.42 +/- 0.07 ms/mm Hg before" 01/01/2006 - "Phenylephrine (1-16 microg kg(-1)) was used to assess baroreflex bradycardia" 05/01/2005 - "Moreover, the slope of the baroreflex bradycardia to phenylephrine was blunted in males (-5.6 +/- 0.3 to -2.9 +/- 0.5) but not in females (-6.5 +/- 0.5 to -5.6 +/- 0.3) during infusion of ANG II, suggesting that, in male mice, infusion of ANG II results in a resetting of the baroreflex control of HR. Ganglionic blockade resulted in greater reduction in BP on day 7 after ANG II infusion in males compared with females (-61.0 +/- 8.9 vs. -36.6 +/- 6.6 mmHg), suggesting an increased contribution of sympathetic nerve activity in arterial BP maintenance in male mice" Get all the results and reference details, order at left...
5.	Clonidine (ST 155)FDA LinkGeneric 06/01/1998 - "In this study, we investigated whether this effect of clonidine is related to facilitation of baroreceptor control of reflex bradycardia" 01/01/1993 - "On the other hand, both low and high doses of clonidine induced bradycardia in the in vivo as well as in vitro studies." 02/01/2008 - "Physicians prescribing clonidine should monitor for bradycardia and advise patients about the high likelihood of initial drowsiness." 02/01/2008 - "RESULTS: There were more incidents of bradycardia in subjects treated with clonidine compared with those not treated with clonidine (17.5% versus 3.4%; p =.02), but no other significant group differences regarding electrocardiogram and other cardiovascular outcomes" 02/20/2007 - "Clonidine-induced bradycardia in conscious alpha2ABC-/- mice was 32.3% (10 microg/kg) and 26.6% (100 microg/kg) of the effect in wild-type mice" Get all the results and reference details, order at left...
6.	Epinephrine (Adrenaline)FDA LinkGeneric 04/08/1985 - "A significant reduction in heart rate was noted during some, but not all, days of the epinephrine infusion period; the onset of bradycardia appeared to be dose-related" 01/01/2003 - "In particular, it remains to be determined if any randomised studies in neonates have helped to establish if the administration of epinephrine in the context of apparent stillbirth or extreme bradycardia might influence mortality and morbidity" 01/01/2003 - "SELECTION CRITERIA: Randomised and quasi-randomised controlled trials of newborns, both pre-term and term, receiving epinephrine for unexpected apparent stillbirth or extreme bradycardia" 06/01/1993 - "To study the hemodynamic effects of graded doses of epinephrine (EPI) in a newborn animal model of hemodynamically significant bradycardia, we performed the following study" 09/01/1950 - "Studies on l-nor-epinephrine: relation of dosage to pressor and bradycardia effect." Get all the results and reference details, order at left...
7.	Atenolol (Tenormin)FDA LinkGeneric 01/01/2007 - "CONCLUSION: The hybrid therapy adopted, OAS associated with the use of atenolol, reduced the rate of recurrent AF and improved the clinical-functional status of patients with symptomatic bradyarrhythmias." 01/01/1990 - "The administration of beta-adrenoceptor blockade (1.0 mg/kg atenolol) improved regional contractile function when heart rate was reduced from 220 to 165 beats/min. Atrial pacing during exercise to prevent the bradycardia following beta-adrenoceptor blockade eliminated the improved regional function and blood flow" 01/01/1981 - "Two patients had to be withdrawn from the study during treatment with atenolol, as they developed severe bradycardia and dyspnoea, respectively" 01/01/2007 - "The residual bradycardia under atenolol (parasympathetic component) was reduced in SHR" 01/01/2007 - "Atenolol attenuated the bradycardia in SHR (-88 +/- 14 vs. -129 +/- 18 beats/min at 90-Hz stimulation) but did not alter the bradycardia in NCR (-116 +/- 16 vs. -133 +/- 13 beats/min)" Get all the results and reference details, order at left...
8.	Amiodarone (Amiodarona)FDA LinkGeneric 08/13/2007 - "CONCLUSION: The risk of bradyarrhythmia requiring pacemaker insertion associated with amiodarone use for AF is significantly greater in women than in men, independent of weight or body mass index." 01/01/2007 - "Bradycardia usually improved after lowering of amiodarone dose" 08/01/2007 - "RESULTS: One-hundred and two patients were included in the study (9 were excluded for bradycardia), and 25 received amiodarone treatment" 10/01/2006 - "In the first 24 h of treatment with amiodarone, 22 patients (10 men and 12 women) were excluded from the study due to sinus bradycardia" 01/15/2003 - "CONCLUSIONS: This study suggests that the use of amiodarone in elderly patients with AF and a previous MI increases the risk of bradyarrhythmia requiring a permanent pacemaker" Get all the results and reference details, order at left...
9.	Serotonin (5 Hydroxytryptamine)IBA 03/01/1983 - "Vagal blockade eliminated the bradycardia but otherwise did not alter the response to left atrial serotonin" 11/01/2007 - "6. In conclusion, in the present study, experimental diabetes evoked changes in both the nature and 5-HT receptor types/subtypes involved in vagally induced bradycardia." 04/01/1997 - "In the present study, we analyzed in conscious rats the effects of microinjections of serotonin (5-HT; pmol range) into the nucleus of the solitary tract (NTS) on basal mean arterial pressure (MAP) and heart rate (HR) and also on the reflex bradycardia induced by the activation of the baro- and chemoreflex evaluated 1 min after 5-HT microinjection into the NTS" 03/01/1986 - "This study has demonstrated, therefore, that the 5-HT induced bradycardia is produced by not only a centrally mediated decrease in sympathetic tone, but also an increase in vagal drive to the heart" 01/01/2008 - "After 4 weeks of treatment, BJR was evaluated by bradycardia responses that were elicited by serotonin administration (2-32 microg/kg(-1))" Get all the results and reference details, order at left...
10.	Metoprolol (Lopressor)FDA LinkGeneric 01/01/2008 - "In two patients (5%), metoprolol was discontinued because of asymptomatic bradycardia" 07/01/2004 - "Bradycardia was observed after the i.v. injection of metoprolol (3 or 10 mg/kg) without differences between the experimental groups" 02/18/1992 - "These results confirm that the ventricular bradycardia induced by the different beta-adrenoceptor antagonists is partly due to ventricular beta-adrenoceptor blockade and to the membrane stabilizing activity of these drugs, and partly to another as yet unknown factor seen especially with the levo-isomers and particularly marked with metoprolol." 03/01/1990 - "At high concentrations (5 and 50 microM), metoprolol alone produced a bradycardia that was probably not related to beta 1 blockade, and this resulted in some nonspecific antiarrhythmic activity" 01/01/1990 - "Notable foetal bradycardia was not observed, in the course of Betaloc administration the decrease of foetal heart rate did not surpass the normal limit values" Get all the results and reference details, order at left...
1744 Drugs and Important Bio-Agents and 5768 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Vagotomy 06/01/1987 - "The CIM bradycardia was not affected by supracollicular decerebration, but substantially reduced by unilateral vagotomy and completely eliminated by bilateral vagotomy" 12/19/2007 - "Ipsilateral or bilateral vagotomy significantly attenuated MCH-induced bradycardia" 10/03/2003 - "The HR response was mediated by vagal excitation as ipsilateral vagotomy abolished the bradycardia response" 05/01/2000 - "Bradycardia and LOS responses were abolished after chronic supranodose vagotomy, indicating that they were due to stimulation of vagal pre-ganglionic neurones, not antidromic stimulation of afferents" 11/01/1997 - "Vagotomy almost abolished the hypotensive response but moderate bradycardia still remained" Get all the results and reference details, order at left...
2.	Resuscitation 12/01/1996 - "The ECG showed extreme bradycardia refractory to resuscitation manoeuvres" 07/01/1996 - "Consensus was identified for deciding on cesarean delivery (after intrauterine resuscitation) 1) after 30 minutes for cases of repetitive late and severe variable decelerations, 2) after 10 minutes in cases of fetal bradycardia, and 3) in all scenarios with decreased beat-to-beat variability of the FHR" 08/01/1995 - "There was a 2% (2 of 113) complication rate, with 1 being a minor incident of fetal bradycardia that responded easily to intrauterine resuscitation" 06/01/1994 - "The infant converted from a slow idioventricular rhythm to sinus bradycardia at 49 minutes (20.4 degrees C) into the resuscitation" 09/01/1993 - "Bradycardia unresponsive to resuscitation occurred, and he died at eight days of age" Get all the results and reference details, order at left...
3.	Artificial Respiration (Mechanical Ventilation) 12/14/2005 - "In C57BL/6J but not FVB/J mice, the bradycardia was abolished with SA under mechanical ventilation" 08/01/1999 - "The infant girl was born by cesarean section, because of fetal bradycardia, after 41 weeks gestation and received mechanical ventilation for 3 days" 05/01/2006 - "Three tests of extubation success were evaluated: (a) expired V e during ET CPAP; (b) ratio of V e during ET CPAP to V e during mechanical ventilation (V e ratio); (c) the spontaneous breathing test (SBT)-the infant passed this test if there was no hypoxia or bradycardia during ET CPAP" 03/01/1986 - "The revealing sign was the occurrence, at age 11 days, of frequent apneas with bradycardia, needing mechanical ventilation associated with adapted antibiotic therapy for 14 days" 01/01/2000 - "OBJECTIVES: Main question: in preterm infants with apnea, does the use of kinesthetic stimulation lead to clinically important reductions in clinical apnea and bradycardia (>50% reduction in number of episodes), use of mechanical ventilation (IPPV) or continuous positive airways pressure (CPAP), and neurodevelopmental disability, without clinically important side effects" Get all the results and reference details, order at left...
4.	Aftercare (After-Treatment) 01/01/1981 - "On the contrary, the bradycardia induced by diving test was significantly greater after treatment than before therapy" 11/01/1998 - "The amount of reduction in apneic spells and bradycardia in the two groups after treatment was compared" 04/01/2000 - "For tachycardia, the values were 254(88) microg before treatment vs 529(78) microg after treatment (P<.05); and for bradycardia, the values were 2.5(1.6) microg before treatment vs 30(13) microg after treatment (P<.05)" 12/01/1992 - "Five patients showed EEG abnormalities just after head positioning, which reversed after removal of head hyperextension; three cases suffered EEG flattening due to severe bradycardia or cardiac arrest before carotid clamping, which promptly reversed after treatment" 03/01/1992 - "Sinus bradycardia and sinus arrhythmia were found in 61.8% and 45.1%, respectively during the first week after treatment" Get all the results and reference details, order at left...
5.	Anesthesia 05/01/1994 - "This study sought to determine the frequency of bradycardia during anesthesia in infants (0 to 1 yr) compared to that in older children, describe causes and morbidity, and identify factors that influence its frequency" 07/01/2008 - "The authors describe a case of clinical use of transesophageal pacing to correct drug-induced bradycardia during anesthesia, surgery, and in the early postoperative period in a geriatric patient with severe cardiovascular comorbidity who has been long receiving a beta-adrenoblocker" 01/01/2008 - "Severe bradycardia during anesthesia will cause cerebral hypoperfusion and this may affect cerebral function" 10/01/2006 - "No bradycardia occurred and no consciousness reported awareness during anesthesia" 10/01/2003 - "A 78-year-old man developed bradycardia with decreased level of consciousness followed by sinus arrest during femoropopliteal bypass surgery under subarachnoid anesthesia" Get all the results and reference details, order at left...
198 Therapies and Procedures and 1250 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

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