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Bowen's Disease (Disease, Bowen)

A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
Also Known As:
Disease, Bowen; Bowen Disease; Bowens Disease; Disease, Bowen's
Networked: 607 relevant articles (59 outcomes, 61 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Basal Cell Carcinoma (Rodent Ulcer)
2. Actinic Keratosis
3. Squamous Cell Carcinoma (Epidermoid Carcinoma)
4. Neoplasms (Cancer)
5. Keratosis

Experts

1. Yu, Hsin-Su: 10 articles (02/2015 - 10/2002)
2. Morton, C A: 9 articles (05/2013 - 10/2000)
3. Lee, Chih-Hung: 8 articles (02/2015 - 09/2004)
4. Liao, Wei-Ting: 8 articles (05/2012 - 10/2002)
5. Chen, Gwo-Shing: 6 articles (02/2015 - 10/2002)
6. Szeimies, Rolf-Markus: 6 articles (06/2010 - 01/2005)
7. Morton, Colin A: 6 articles (01/2007 - 04/2002)
8. Kawana, Seiji: 5 articles (08/2014 - 09/2003)
9. Hong, Chien-Hui: 4 articles (02/2015 - 05/2011)
10. Nakajima, Susumu: 4 articles (08/2014 - 10/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bowen's Disease:
1. 1-phenyl-3,3-dimethyltriazene (PDT)IBA
2. imiquimod (Aldara)FDA LinkGeneric
3. Fluorouracil (Carac)FDA LinkGeneric
4. ArsenicIBA
5. Aminolevulinic Acid (Levulan)FDA Link
6. Keratins (Keratin)IBA
7. AntibodiesIBA
8. AntigensIBA
9. Cadherins (E-Cadherin)IBA
10. AcitretinFDA Link

Therapies and Procedures

1. Photochemotherapy (Photodynamic Therapy)
2. Cryotherapy (Therapy, Cold)
3. Gas Lasers
4. Radiotherapy
5. Dye Lasers