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Botulism

A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
Also Known As:
Botulism, Toxico-Infectious; Toxico-Infectious Botulism; Botulism, Toxico Infectious; Infantile Botulism; Toxico Infectious Botulism; Botulism, Infantile
Networked: 658 relevant articles (20 outcomes, 38 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Tetanus
2. Toxemia
3. Anthrax
4. Plague (Bubonic Plague)
5. Tularemia

Experts

1. Johnson, Eric A: 18 articles (01/2015 - 09/2003)
2. Smith, Leonard A: 17 articles (09/2015 - 11/2006)
3. Janda, Kim D: 14 articles (08/2014 - 10/2005)
4. Tepp, William H: 13 articles (01/2015 - 09/2003)
5. Kalb, Suzanne R: 12 articles (07/2015 - 01/2010)
6. Barr, John R: 12 articles (07/2015 - 01/2010)
7. Baudys, Jakub: 10 articles (07/2015 - 01/2010)
8. Pellett, Sabine: 10 articles (01/2015 - 04/2008)
9. Smith, Theresa J: 9 articles (09/2015 - 01/2010)
10. Popoff, Michel R: 8 articles (11/2015 - 08/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Botulism:
1. Botulinum Toxins (Botulinum Toxin)IBA
2. DNA (Deoxyribonucleic Acid)IBA
3. Guanidine (Guanidine Nitrate)FDA Link
4. AntitoxinsIBA
5. toosendaninIBA
6. Foodborne botulismIBA
7. Edrophonium (Tensilon)FDA LinkGeneric
8. 3,4-diaminopyridineIBA
9. AntibodiesIBA
10. botulism immune globulinIBA

Therapies and Procedures

1. Chinese Traditional Medicine (Traditional Chinese Medicine)
2. Therapeutics
3. Artificial Respiration (Mechanical Ventilation)
4. Dilatation and Curettage (D&C)
5. Length of Stay