|1.||Mood Disorders (Mood Disorder)
|1.||Solbrig, Marylou V: 3 articles (11/2013 - 07/2002)|
|2.||Ogino, Tomoaki: 2 articles (12/2011 - 02/2010)|
|3.||Banerjee, Amiya K: 2 articles (12/2011 - 02/2010)|
|4.||Boucraut-Baralon, Corine: 1 article (07/2015)|
|5.||Addie, Diane D: 1 article (07/2015)|
|6.||Gruffydd-Jones, Tim: 1 article (07/2015)|
|7.||Egberink, Herman: 1 article (07/2015)|
|8.||Möstl, Karin: 1 article (07/2015)|
|9.||Thiry, Etienne: 1 article (07/2015)|
|10.||Horzinek, Marian C: 1 article (07/2015)|
02/01/2005 - "Vaccine-induced protection against Borna disease in wild-type and perforin-deficient mice."
11/01/2001 - "Taken together, these results demonstrate that CD8(+) T cells mediate Borna disease independent of perforin. "
11/01/2001 - "When a defective perforin gene was introduced into the genetic background of the Borna disease-susceptible mouse strain MRL, the resulting perforin-deficient mice developed strong neurological disease in response to infection indistinguishable from that of their perforin-expressing littermates. "
01/01/1993 - "Biology and neurobiology of Borna disease viruses (BDV), defined by antibodies, neutralizability and their pathogenic potential."
10/01/1987 - "[Findings with nuclear magnetic resonance tomography in psychiatric patients with and without serum antibodies to the virus of Borna disease]."
07/01/2015 - "Serology is of little value; cats without signs of Borna disease may be seropositive and yet not every cat with BDV infection has detectable levels of antibodies. "
01/01/2001 - "These antibodies, directed against the major glycoprotein (gp94) of BDV, were able to prevent Borna disease if given prophylactically. "
02/01/1999 - "For a serological diagnostic test for Borna disease (BD), we developed a capture ELISA with specificity and sensitivity based on detection of antibodies against BD virus (BDV) p40 protein. "
|4.||RNA (Ribonucleic Acid)IBA
11/01/1998 - "A single-tube RT-PCR method for the detection of Borna disease viral genomic RNA."
09/01/2003 - "Trafficking of viral genomic RNA into and out of the nucleus: influenza, Thogoto and Borna disease viruses."
12/01/1993 - "The presence of Borna disease virus (BDV)-specific RNA was traced by the reverse transcriptase-polymerase chain reaction in conjunctival fluid, nasal secretions and saliva of horses which were seropositive but did not have any history of clinical Borna disease. "
05/01/1999 - "Previous studies have found a high prevalence of serum antibodies as well as Borna disease viral antigens (BDVAGs) and RNA in the white blood cells of psychiatric patients, especially those with affective disorders. "
11/12/1996 - "Immune cells invading the central nervous system (CNS) in response to Borna disease virus (BDV) antigens are central to the pathogenesis of Borna disease (BD). "
07/01/1994 - "Based on the immunohistochemical demonstration of viral antigen and on the histological brain lesions, Borna disease was diagnosed in a cow and a bull which had suffered from a severe, subacute progressive disorder of the central nervous system. "
12/01/1990 - "Borna disease (BD) is a neurologic syndrome characterized by profound disturbances in behavior and the accumulation of specific antigens in limbic system neurons. "
02/01/1986 - "A virus-specific antigen was extracted from brains of rats and from MDCK cells infected with Borna disease (BD) virus and purified to homogeneity by immunoaffinity chromatography and HPLC. "
02/27/1998 - "Spontaneous Borna disease in sheep and horses: immunophenotyping of inflammatory cells and detection of MHC-I and MHC-II antigen expression in Borna encephalitis lesions."
|7.||Messenger RNA (mRNA)IBA
10/01/1993 - "The correlation of iNOS and cNOS mRNA expression with the development of neurological disease, as well as the enhanced expression of iNOS within brain regions with inflammatory lesions, strongly suggests that NO may contribute to pathogenesis of Borna disease."
02/01/1992 - "Since IFN-gamma and CD8 mRNA levels were still highly elevated in the chronic phase of Borna disease, it is likely that CD8+ T lymphocytes act to reduce inflammation and to ameliorate neurological signs during the chronic phase of infection."
12/01/2011 - "mRNAs of vesicular stomatitis virus (VSV), a prototype of nonsegmented negative strand (NNS) RNA viruses (e.g., rabies, measles, mumps, Ebola, and Borna disease viruses), possess the 5'-terminal cap structure identical to that of eukaryotic mRNAs, but the mechanism of mRNA cap formation is distinctly different from the latter. "
10/01/1993 - "The putative role of nitric oxide in the neuropathogenesis of Borna disease was investigated by determining changes in the expression of inducible nitric oxide synthase (iNOS) mRNA and constitutively expressed NOS (cNOS) mRNA in brains of Borna disease virus (BDV)-infected rats. "
|8.||Proteins (Proteins, Gene)IBA
06/01/1990 - "Borna disease (BD) is a neurologic syndrome characterized by behavioral disturbances and the accumulation of specific proteins in limbic system neurons. "
01/01/2000 - "Molecular ratio between borna disease viral-p40 and -p24 proteins in infected cells determined by quantitative antigen capture ELISA."
02/23/2010 - "Interestingly, H1227 is part of the histidine-arginine (HR) motif, which is conserved within the L proteins of the NNS RNA viruses including rabies, measles, Ebola, and Borna disease viruses. "
|9.||Complement System Proteins (Complement)IBA
11/01/1991 - "Bone marrow from PTI-NB rats contained a complement of inflammatory cells capable of inducing Borna disease. "
05/01/1995 - "Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis."
|10.||Amantadine (Aman)FDA LinkGeneric
03/29/1997 - "Depression, Borna disease, and amantadine."
03/01/1998 - "These experiments, although revealing negative results and obtained using a virus from a natural case of Borna disease grown after isolation in vitro for a long period of time, should caution from the general use of amantadine as a curative agent against BDV infection as has been implicated recently [Bode et al. (1997) Lancet 349:178-179]."
|1.||Bone Marrow Transplantation (Transplantation, Bone Marrow)
11/15/1991 - "Intraperitoneal injection of the recombinant molecule, rTGF-beta 2, started on the day of infection at a dose of either 1 micrograms given every day or every other day for 8 consecutive days or 2 micrograms every third day, was found to result in the absence of typical Borna disease symptoms at 14 days after infection in most of the TGF-beta-treated rats, a time point at which all infected control animals not treated with rTGF-beta 2 showed distinct signs of Borna disease. "