Border Disease

11/15/2000 - "Two hundred and forty nine sera were initially detected as CSF positive but confirmed secondarily as positive for border disease (BD) antibodies. "
04/01/2000 - "The prevalence of antibodies to Border Disease was 20% in sheep of breeding associations and 65% in those of independent sheep owners."
04/01/1987 - "A total of 20 ovine serum samples, which had been collected from animals with or without border disease, were compared by ELISA and serum neutralization test for the detection of border disease-specific antibodies. "
01/01/1981 - "Despite Border disease and bovine virus diarrhoea being endemic among sheep and cattle in counties bordering Wales, none of the cord blood samples contained antibodies to Border disease or bovine virus diarrhoea viruses. "
10/01/1977 - "Anti-myelin antibodies in the serum of lambs with experimental Border Disease."

01/01/2002 - "Vaccination with these vaccines caused outbreaks of Border Disease in Tunisia. "
10/12/1996 - "The apparent natural transmission of orf virus from clinically normal ewes to susceptible sheep was observed during a border disease vaccine experiment. "
02/01/1991 - "Outbreaks of border disease in goats induced by a pestivirus-contaminated orf vaccine, with virus transmission to sheep and cattle."
10/01/1991 - "Using the panel it was possible to identify specifically all strains and isolates of hog cholera virus, hog cholera vaccines derived from 'C' strains, and most strains of bovine viral diarrhoea/border disease (BVD/BD) viruses (including those isolated from pigs). "
10/01/2013 - "In this article, we summarize the clinical syndromes and routes of transmission of BVD, CSF and border disease, discuss currently approved vaccines, review efforts to develop antiviral therapies for use in outbreak control and suggest promising directions for future research. "

10/01/1993 - "These results suggested that preventing mobilization of AA from lipid stores for effective immune responses may be a viral strategy of BD virus that is associated with long term border disease effects."
03/01/1975 - "Spinal cord lipids and myelin composition in border disease (hypomyelinogenesis congenita) of lambs."
01/01/1966 - "A comparison of the composition of white matter lipids in swayback and border disease of lambs."
01/01/1977 - "The structure of the epidermis and dermis, and the distribution of reticulin, glycogen, lipid and sulphydryl groups in the skin have been examined in control and Border disease affected sheep fetuses at 95 and 115 days' gestation. "

04/01/2016 - "The whole virus antigen cannot differentiate CSFV from other pestiviruses as it cross reacts with border disease and bovine viral diarrhoea viruses. "
11/01/1978 - "Detection of Border disease antigen in tissues of affected sheep and in cell cultures by immunofluorescence."
03/01/2008 - "Macroscopic anomalies that were typical of border disease included scoliosis, brachygnathism, prognathism, arthrogryposis, hydranencephaly, cerebellar hypoplasia, and hairy fleece; pestiviral antigen was detected by IHC in the brain, liver, lungs, and kidneys. "
10/31/2006 - "Between 2001 and 2002, samples from 1,413 animals in 21 Spanish small ruminant flocks, most of them with animals showing clinical signs compatible with Border disease (BD), were screened for the presence of Pestivirus antigen and antibodies by an indirect peroxidase monolayer assay (IPMA) and the virus neutralization test (VNT), respectively. "

01/01/2019 - "Border disease virus (BDV) is a positive-sense, single-stranded RNA pestivirus that mainly infects and causes border disease (BD) in sheep and goats worldwide. "
02/01/2017 - "Initial diagnosis of 'border disease-like' was established, based on clinical signs, serology and/or RNA detection by a pan-pestivirus RT-PCR. "
03/01/2004 - "Bovine viral diarrhea virus 2 (BVDV-2) strains, isolated from sheep showing clinical symptoms of border disease, have been evaluated by the palindromic nucleotide substitution (PNS) method at the three variable loci (V1, V2 and V3) in the 5'-untranslated region (UTR) of genomic RNA. "

07/01/1979 - "The transfer of copper from ewes with Border disease to their lambs."
01/31/1976 - "Copper metabolism in experimental Border disease."
09/07/1974 - "Copper metabolism and the composition of wool in Border disease."

03/01/1987 - "Experimentally induced ovine border disease: extensive hypomyelination with minimal viral antigen in neonatal spinal cord."
10/01/1980 - "The distribution and significance of border disease viral antigen in infected lambs and foetuses."
11/01/1978 - "Border disease viral antigen was demonstrated in cell cultures derived from the brain, kidney and testicle of six out of seven lambs despite the presence of neutralising antibody against bovine virus diarrhoea virus in three of them. "

03/01/1996 - "The nucleotide and amino acid sequences of these E2s had only a 60-65% homology with group I BVDV E2s but >90% homology with the E2 of a subgroup of sheep border disease viruses. "
03/01/2004 - "Bovine viral diarrhea virus 2 (BVDV-2) strains, isolated from sheep showing clinical symptoms of border disease, have been evaluated by the palindromic nucleotide substitution (PNS) method at the three variable loci (V1, V2 and V3) in the 5'-untranslated region (UTR) of genomic RNA. "

12/01/1990 - "The peroxidase-antiperoxidase technique was used to determine the cellular localization of Border Disease (BD) virus in cryostat sections of fetal and newborn lamb spinal cord following experimental infection by maternal inoculation in early gestation. "
10/31/2006 - "Between 2001 and 2002, samples from 1,413 animals in 21 Spanish small ruminant flocks, most of them with animals showing clinical signs compatible with Border disease (BD), were screened for the presence of Pestivirus antigen and antibodies by an indirect peroxidase monolayer assay (IPMA) and the virus neutralization test (VNT), respectively. "

06/01/1996 - "Restriction endonuclease enzyme AvaI and Bg/I digestion of 5' NC genomic region PCR products suggested that Frijters strain belongs to the border disease viruses (BDV). "
04/01/1987 - "An enzyme-linked immunosorbent assay (ELISA) was established for the rapid detection of specific antibodies against the causative agent of border disease in ovine sera. "

10/01/2013 - "In this article, we summarize the clinical syndromes and routes of transmission of BVD, CSF and border disease, discuss currently approved vaccines, review efforts to develop antiviral therapies for use in outbreak control and suggest promising directions for future research. "