|1.||Hage, Chadi A: 8 articles (04/2014 - 01/2007)|
|2.||Wheat, L Joseph: 8 articles (02/2014 - 11/2006)|
|3.||Bradsher, Robert W: 5 articles (01/2014 - 04/2008)|
|4.||Klein, B S: 5 articles (12/2007 - 02/2000)|
|5.||Scalarone, G M: 5 articles (09/2005 - 10/2002)|
|6.||Kauffman, Carol A: 4 articles (08/2012 - 06/2008)|
|7.||Durkin, Michelle: 4 articles (02/2011 - 10/2004)|
|8.||Durkin, Michelle M: 3 articles (11/2015 - 03/2012)|
|9.||Davis, Thomas E: 3 articles (02/2014 - 01/2007)|
|10.||Klein, Bruce S: 3 articles (02/2014 - 06/2002)|
|1.||Ketoconazole (Nizoral)FDA LinkGeneric
01/15/1983 - "Four dogs with blastomycosis were treated with ketoconazole, and good results were obtained in 3 of the 4 cases. "
01/15/1983 - "The results of the study suggested that ketoconazole is effective for the treatment of canine blastomycosis."
09/01/1997 - "Ketoconazole was shown to be effective for less than overwhelming blastomycosis, but adverse effects were relatively common. "
12/01/1994 - "Treatment of isolated laryngeal blastomycosis with ketoconazole. "
01/01/1993 - "Therapy of blastomycosis has been broadened with the addition of ketoconazole. "
|2.||Amphotericin B (Amphotericin)FDA LinkGeneric
03/01/2008 - "The patient was treated successfully with amphotericin for blastomycosis of the eye, lung, and thyroid. "
12/01/1985 - "Amphotericin B is effective in therapy for blastomycosis but causes a number of serious adverse reactions. "
04/01/1967 - "[Multivisceral blastomycosis with pulmonary predominance in a Frenchman of Tunisian origin cured by amphotericin B]."
01/01/2015 - "Classically, cerebral blastomycosis has been treated with amphotericin B. "
05/01/2012 - "The lipid formulation of amphotericin B is the initial drug of choice for central nervous system blastomycosis, but it is costly and associated with significant toxicity. "
03/01/2014 - "Serum and urine Blastomyces antigen concentrations as markers of clinical remission in dogs treated for systemic blastomycosis."
12/01/1995 - "Serologic tests for the diagnosis of blastomycosis have had inadequate sensitivity, but results are improved with enzyme immunoassay (EIA) with A-antigen of Blastomyces dermatitidis. "
02/01/1981 - "Seven of 10 patients with proved blastomycosis had positive results on DID assays for antibody to the A antigen of Blastomyces dermatitidis. "
01/01/2013 - "The aim of this study was to evaluate the diagnostic sensitivity of Blastomyces dermatitidis yeast lysate antigens with respect to antibody detection in dogs with blastomycosis. "
04/01/2004 - "The study may prove valuable in the development of antigen candidates for blastomycosis serodiagnosis."
|4.||Itraconazole (Sporanox)FDA LinkGeneric
03/01/2013 - "Successful treatment of pulmonary blastomycosis in a pregnant woman using itraconazole."
05/01/2011 - "Itraconazole is recommended for treatment of blastomycosis in dogs. "
04/15/2004 - "To compare prevalence of organisms and histologic changes in eyes from dogs with blastomycosis that were either untreated or undergoing treatment with itraconazole. "
04/01/2004 - "Chronic blastomycosis should always be treated with systemic antifungal therapy, and oral itraconazole is the drug of choice for mild to moderate forms of the disease. "
04/01/2000 - "Thus, itraconazole is the initial treatment of choice for nonlife-threatening non-CNS blastomycosis."
|5.||Fluconazole (Zonal)FDA LinkGeneric
02/01/1995 - "We conclude that fluconazole (200 mg to 400 mg daily) given for at least 6 months is moderately effective treatment for blastomycosis."
05/01/2011 - "Fluconazole is associated with survival to clinical remission in 75% of dogs with blastomycosis. "
08/01/1997 - "To examine the usefulness of higher doses of fluconazole therapy for this disorder, we conducted a multicenter, randomized, open-label study to determine the efficacy and safety of two different daily doses of fluconazole (400 and 800 mg) in the treatment of non-life-threatening blastomycosis. "
02/01/1995 - "We conducted a multicenter, randomized, open-label pilot trial comparing two daily doses of fluconazole (200 mg and 400 mg) in the treatment of non-life-threatening, non-CNS blastomycosis. "
05/01/2012 - "This case report details a patient with primary pulmonary blastomycosis with dissemination to the skin, one joint, and the brainstem that was successfully treated solely with high-dose fluconazole."
|6.||voriconazole (Vfend)FDA LinkGeneric
02/01/2001 - "We evaluated the efficacy of voriconazole, a new broad-spectrum triazole antifungal compound, in the treatment of murine pulmonary blastomycosis. "
02/01/2001 - "Efficacy of voriconazole in treatment of murine pulmonary blastomycosis."
10/01/2009 - "Further studies are needed to fully elucidate the role of voriconazole in the treatment of CNS blastomycosis. "
10/01/2009 - "To date, no clinical trials have evaluated the use of voriconazole in treating CNS blastomycosis. "
10/01/2009 - "Search terms included voriconazole, blastomyces, blastomycosis, CNS, cerebral, and central nervous system. "
|7.||liposomal amphotericin BFDA Link
12/15/1996 - "Amphotericin B lipid complex was a safe and effective treatment for blastomycosis in these dogs."
05/01/2001 - "This is the first reported case of cerebral blastomycosis successfully treated with amphotericin B lipid complex."
12/15/1996 - "To evaluate efficacy and nephrotoxicity of amphotericin B lipid complex used for treatment of dogs with naturally developing blastomycosis. "
12/15/1996 - "Use of an amphotericin B lipid complex for treatment of blastomycosis in dogs."
04/01/2006 - "Recurrent central nervous system blastomycosis in an immunocompetent child treated successfully with sequential liposomal amphotericin B and voriconazole."
|8.||Miconazole (Monistat)FDA LinkGeneric
06/01/1979 - "Blastomycosis treated successfully with miconazole."
06/01/1979 - "Miconazole seems to be effective and safe in the treatment of blastomycosis."
10/15/1993 - "Subconjunctival miconazole and anterior segment blastomycosis."
06/01/1979 - "A case of disseminated blastomycosis is described, which was treated with miconazole orally. "
08/01/1978 - "Miconazole treatment of relapsed pulmonary blastomycosis."
01/01/1985 - "Effective clinical use has been demonstrated in patients with cutaneous and systemic candidiasis, aspergillosis, blastomycosis, coccidioidomycosis, cryptococcus and systemic candidiasis, aspergillosis, blastomycosis, coccidioidomycosis, cryptococcus and histoplasmosis. "
03/01/1989 - "Similarly, good to excellent response rates (clinical cure or marked improvement) are achieved in paracoccidioidomycosis, histoplasmosis, sporotrichosis, blastomycosis, systemic candidiasis, coccidioidomycosis, chromomycosis, aspergillosis and cryptococcosis. "
01/24/1983 - "Excellent results were obtained in six cases of chronic mucocutaneous candidiasis, with restoration of immunologic disturbances; 23 cases of systemic candidiasis, including new aspects of heroin addicts with cutaneous, ocular, or osteoarticular manifestations; eight cases of histoplasmosis, five due to Histoplasma capsulatum and three to Histoplasma duboisii, with cure in seven and remission in one; one case of African blastomycosis (Blastomyces dermatitidis); three cases of mycetoma, two due to Monosporium apiospermum, one due to a dematiacious fungus; three cases of entomophthoromycosis with cure; one case of fungal arthritis, due to new hyphomycete similar to M. "
09/01/1997 - "Efficacy of nikkomycin Z against experimental pulmonary blastomycosis."
09/01/1997 - "Overall, nikkomycin Z given orally was well tolerated, had good activity against blastomycosis, and could result in biological cure, thus producing results equivalent to those of parenteral amphotericin B."
09/01/1997 - "In vitro, nikkomycin Z had good activity against Blastomyces dermatitidis, with an MIC of 0.78 microg/ml and a minimal fungicidal concentration of 3.1 microg/ml. The efficacies of various treatment durations (3, 5, or 10 days) and doses (200, 400, or 1,000 mg/kg of body weight) of nikkomycin Z given twice daily were compared with those of itraconazole at 200 mg/kg given twice daily and amphotericin B at 6.25 mg/kg in a murine model of pulmonary blastomycosis. "
04/01/1990 - "In vivo, nikkomycin Z was more effective than nikkomycin X, was also found to be superior on a milligram per milligram basis to the majority of azoles tested in the models of coccidioidomycosis and blastomycosis, and was moderately effective in histoplasmosis. "
|1.||Transplantation (Transplant Recipients)
01/01/1993 - "Other reported cases of blastomycosis in transplant recipients are summarized. "
01/01/1993 - "Blastomycosis in transplant recipients: report of a case and review."
06/01/1990 - "A case of disseminated blastomycosis in a male renal transplant recipient is presented. "
10/01/1985 - "A renal transplant recipient presented with pulmonary blastomycosis. "
12/01/1984 - "Disseminated inoculation blastomycosis in a renal transplant recipient."
03/01/2014 - "21 dogs with newly diagnosed blastomycosis monitored until clinical remission (Treatment Phase), and 27 dogs monitored over 1 year from the time of antifungal discontinuation or until clinical relapse (After Treatment Phase). "
04/01/2006 - "We report a case of central nervous system blastomycosis occurring 18 months after treatment of pulmonary blastomycosis in an immunocompetent child. "
01/01/2002 - "CT is therefore recommended as a screening test for intracranial blastomycosis in dogs and also as an imaging modality for follow-up evaluation after treatment. "
05/01/2000 - "For 93 serial serum samples from 29 dogs with blastomycosis, the mean anti-WI-1 titer was 1:18,761 at the time of diagnosis, and decreased to a mean of 1:1,338 by 210 days after treatment was initiated. "
12/15/1996 - "One dog died of an unrelated cause 5.5 months after treatment, but did not have clinical signs of blastomycosis at the time of death. "
09/01/1996 - "Dissemination of pulmonary blastomycosis after thoracotomy."
03/01/1992 - "The diagnosis of pulmonary blastomycosis was made at thoracotomy. "
04/01/1991 - "If these risk factors are kept in mind, the diagnosis of blastomycosis may be established before a thoracotomy is performed unnecessarily."
03/01/1981 - "In five cases of blastomycosis, invasive procedures were required before the diagnosis was established; these included thoracotomy in two cases and craniotomy in a third case. "
08/01/1977 - "Since cytologic techniques are simple, readily available, and rapid, they can be helpful in differentiating pulmonary neoplasms from pulmonary blastomycosis, thus reducing the need for diagnostic thoracotomies."
04/01/2012 - "However, 15 weeks after the onset of salvage therapy, he succumbed to polymicrobial sepsis despite treatment with prophylactic anti-infectives, with necropsy revealing disseminated blastomycosis and relapsed HLH. "
04/01/2009 - "In a retrospective review of 24 patients with histoplasmosis, blastomycosis, or coccidioidomycosis treated with voriconazole (most for salvage therapy), the outcome was favorable (improved or stable) for 22 (95.8%) within 2 months of starting voriconazole and for 20 (83.3%) at the last follow-up. "
08/01/2014 - "Peritoneal blastomycosis is a rare clinical entity and, to our knowledge, this patient represents the first known case of peritoneal blastomycosis in a solid organ transplant recipient. "
07/01/2009 - "We describe a patient who underwent a renal transplant and developed pulmonary blastomycosis."
12/01/2007 - "After cure, post-transplant blastomycosis may not require lifelong antifungal suppression."
12/01/2007 - "Rejection did not precede any case of post-transplant blastomycosis. "
12/01/2007 - "From 1986 to 2004, we identified 11 cases of post-transplant blastomycosis with 64% occurring between 2000 and 2004. "