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Bladder Exstrophy (Exstrophy, Bladder)

A birth defect in which the URINARY BLADDER is malformed and exposed, inside out, and protruded through the ABDOMINAL WALL. It is caused by closure defects involving the top front surface of the bladder, as well as the lower abdominal wall; SKIN; MUSCLES; and the pubic bone.
Also Known As:
Exstrophy, Bladder; Bladder Extrophy; Exstrophy of the Bladder; Urinary Bladder Exstrophy; Bladder Exstrophies; Bladder Extrophies; Exstrophies, Bladder; Exstrophies, Urinary Bladder; Exstrophy, Urinary Bladder; Extrophies, Bladder; Extrophy, Bladder; Urinary Bladder Exstrophies
Networked: 321 relevant articles (4 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Epispadias
2. Urinary Incontinence
3. Hypospadias
4. Prolapse
5. Diaphragmatic Hernia

Experts

1. Gearhart, John P: 26 articles (05/2015 - 03/2003)
2. Stec, Andrew A: 5 articles (05/2013 - 05/2011)
3. Gearhart, J P: 5 articles (04/2008 - 03/2000)
4. Di Carlo, Heather N: 4 articles (05/2015 - 07/2014)
5. Reutter, Heiko: 4 articles (10/2014 - 10/2011)
6. Boyadjiev, Simeon A: 4 articles (10/2014 - 05/2005)
7. Sponseller, Paul D: 4 articles (10/2014 - 06/2006)
8. Baradaran, Nima: 4 articles (05/2013 - 07/2012)
9. Inouye, Brian M: 3 articles (05/2015 - 07/2014)
10. Tourchi, Ali: 3 articles (05/2015 - 11/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bladder Exstrophy:
1. Anorectal atresiaIBA
10/01/2013 - "Most common cause for VUR was Primary (60%), followed by posterior urethral valve (PUV) (19%), bladder exstrophy (5%), anorectal malformation (ARM), epispadias, and duplex system. "
10/01/2006 - "Patients with bladder exstrophy and many previous bladder procedures are more exposed to complications such as erosion compared with patients with epispadias or anorectal malformation. "
10/01/2006 - "Instead there were bladder exstrophy in 12 patients, anorectal malformation with a rectourethral or vesical fistula in 7 and epispadias in 4. A bladder neck cuff between 5.5 and 7.5 cm, and a 61-70 balloon were used in all patients. "
01/01/1990 - "Report of the observation of a female newborn presenting a complex malformative set: distal anorectal malformation without fistula; bladder exstrophy without epispadias, with cutaneous bridge; congenital urethrovaginal fistula; malformative sexual ambiguity with bulky genital tubercle, whole urethra, urethral meatus on the apex of the genital tubercle, associated with a mid labial genital joint and a high genital orifice; unilateral multicystic kidney; vertebral abnormalities with supernumerary thoracolumbar vertebrae; no karyotype abnormalities and no familial pathological history; no endocrine abnormalities. "
01/01/1988 - "None of these boys referred to a history of a known urological anomaly, urinary tract infection, haematuria, palpable mass in the renal region, bladder extrophy, epispadias, hypospadias or anorectal malformation. "
2. Hereditary renal agenesisIBA
3. Interleukin-18 (Interleukin 18)IBA
4. Interleukin-13IBA
5. AntigensIBA
6. Omphalocele exstrophy imperforate anusIBA
7. CosmeticsIBA
8. PlasticsIBA
9. CollagenIBA
10. Sacral agenesisIBA

Therapies and Procedures

1. Osteotomy
2. Urinary Diversion (Ileal Conduit)
3. Transplantation (Transplant Recipients)
4. External Fixators
5. Transplants (Transplant)