|1.||Wolf, Barry: 14 articles (10/2015 - 03/2002)|
|2.||Zempleni, Janos: 14 articles (12/2013 - 11/2003)|
|3.||Press, Oliver W: 11 articles (01/2015 - 05/2002)|
|4.||Wilbur, D Scott: 10 articles (12/2011 - 05/2002)|
|5.||Pagel, John M: 9 articles (01/2015 - 03/2003)|
|6.||Paganelli, Giovanni: 8 articles (04/2015 - 07/2003)|
|7.||Lin, Yukang: 8 articles (01/2015 - 07/2006)|
|8.||Kim, Jong Seung: 6 articles (11/2015 - 03/2013)|
|9.||Zhang, Xian-Zheng: 6 articles (10/2015 - 02/2008)|
|10.||Shibata, Katsumi: 6 articles (01/2015 - 12/2007)|
02/15/2000 - "Subsequent administration of (90)Y-1,4,7, 10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-biotin achieved peak uptake at the tumor within 2 hr while >80% of the radioactivity was eliminated in the urine. "
01/01/2015 - "Knowing that the CD44(+) is a commonly used cancer-stem-cell biomarker, our targeted biotin-MBs could be a potent tool to sort cancer stem cells from dissected tumor tissue for use in preclinical experiments and clinical trials."
01/30/2013 - "We investigated the likelihood of selecting this cell line (T47D) as an in vitro cell culture model to study biotin-conjugated anti-cancer drugs/drug delivery systems."
01/01/2010 - "In this study, cancer cells were chemically tagged with biotin and then magnetically labeled with anti-biotin SPIOs. "
10/01/2009 - "In vivo SPECT/CT imaging of xenografted PC-3 tumors in SCID mice with the three-step pretargeting method was superior to that of the two-step pretargeting method, and, importantly, blocking studies demonstrated specificity of tumor uptake of (111)In-labeled biotin in the three-step pretargeting scheme. "
|2.||Biotinidase Deficiency (Multiple Carboxylase Deficiency, Late Onset)
03/04/1994 - "Biotinidase deficiency is an inherited metabolic disorder of biotin recycling that is characterized by neurological and cutaneous abnormalities, and can be successfully treated with biotin supplementation. "
10/01/2015 - "He was ultimately shown to have profound biotinidase deficiency due to a novel missense mutation and was partly improved by oral biotin therapy. "
07/01/2003 - "A follow-up of the case indicated the efficacy, of biotin supplementation in biotinidase deficiency."
12/01/1997 - "Biotinidase deficiency was confirmed biochemically and she responded well to biotin therapy. "
03/01/2015 - "Biotinidase deficiency is an autosomal recessive inborn error of biotin metabolism. "
04/01/2008 - "The aim of our study is to use In-Biotin to diagnose vertebral infections. "
01/01/2015 - "During infection BplA seems primarily employed to maximize the efficiency of biotin utilization without limiting the expression of biotin biosynthetic genes, representing a novel adaptation strategy that may also be used by other intracellular pathogens. "
01/01/2015 - "Mice fed with a biotin-rich diet show significantly reduced EHEC adherence, indicating that biotin might be useful to prevent EHEC infection in humans. "
01/01/2015 - "Enterohemorrhagic Escherichia coli senses low biotin status in the large intestine for colonization and infection."
01/01/2015 - "As biotin is used as a growth factor by certain bacteria, (111)In-biotin is useful to diagnose spinal infections. "
04/01/2014 - "Biotin may be considereduseful for the treatment of skin rash causedby EGFR-TKIs. "
04/01/2014 - "In all patients, administration of biotin reduced the skin rash. "
05/01/1997 - "The fourth patient required a dose of 100 mg biotin/d before her skin rash disappeared. "
10/01/2001 - "Skin lesions (seborrheic rash, alopecia) were improved in our patients after biotin (10 mg/day) supplementation. "
01/01/1990 - "One child, who was not initially treated with biotin, later developed hypotonia, hair loss, and skin rash, which resolved with biotin therapy. "
01/01/2010 - "In the pre-targeting study, FM3A mouse breast carcinoma-implanted mice were injected with anti-MT1-MMP mAb-SAv, followed 72 h later with radioiodinated biotin, (3-[123/125I]iodobenzoyl)norbiotinamide (123/125I-IBB). "
10/15/2007 - "Both biotin-KCCYSL and 111In-DOTA(GSG)-KCCYSL were capable of binding ErbB-2-expressing human breast carcinoma cells in vitro. "
08/01/2002 - "CPT-PEG and CPT-PEG-biotin conjugates were synthesized and studied in vitro in A2780 sensitive and A2780/AD multidrug-resistant human ovarian carcinoma cells. "
08/01/2002 - "While biotin-pHPMA could be detected intracytoplasmically in liver and spleen, a predominantly interstitial localisation was observed within the anaplastic prostate carcinoma (Dunning R3327-AT1). "
11/01/2000 - "We have analyzed a series of 100 invasive ductal breast carcinomas without lymph node invasion both by IHC, using the CB11 monoclonal antibody and a sensitive Auidin Biotin Complex (ABC) immunodetection system, and by FISH, using the Oncor Inform HER-21neu (ERBB2) gene amplification detection system as reference technique. "
|3.||DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)
|6.||Folic Acid (Vitamin M)
|9.||Late-onset multiple carboxylase deficiency
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)
|3.||Renal Dialysis (Hemodialysis)