Biliary Tract Neoplasms (Biliary Tract Cancer)

Subscribe to Selected New Research on Biliary Tract Neoplasms

196 relevant articles (9 outcomes, 56 trials/studies) found for this Disease

Description: Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.

Also Known As:

Biliary Tract Cancer; Cancer of the Biliary Tract; Neoplasms, Biliary Tract; Biliary Tract Cancers; Biliary Tract Neoplasm; Cancer, Biliary Tract; Cancers, Biliary Tract; Neoplasm, Biliary Tract; Cancer of Biliary Tract

Relationship Network

Disease Context: Research Results

Neoplasms: 386513

Neoplasms by Site: 1

Digestive System Neoplasms: 52

Biliary Tract Neoplasms: 196

Gallbladder Neoplasms: 499

Bile Duct Neoplasms: 218

Digestive System Diseases: 29

Biliary Tract Diseases: 303

Biliary Tract Neoplasms: 196

Gallbladder Neoplasms: 499

Bile Duct Neoplasms: 218

Digestive System Neoplasms: 52

Biliary Tract Neoplasms: 196

Gallbladder Neoplasms: 499

Bile Duct Neoplasms: 218

Related Diseases

1.	Biliary Tract Neoplasms (Biliary Tract Cancer)
2.	Cholangiocarcinoma
3.	Neoplasms (Cancer)
4.	Hepatocellular Carcinoma (Hepatoma)
5.	Gallstones (Gallstone)
40 Diseases and 71 more articles analyzed in the Research Interface, order at left...

Experts

1.	Okusaka, Takuji: 9 articles (11/2007 - 12/2002)
2.	Rashid, Asif: 6 articles (05/2008 - 05/2005)
3.	Hsing, Ann W: 6 articles (05/2008 - 05/2005)
4.	Han, Tian-Quan: 5 articles (05/2008 - 05/2005)
5.	Zhang, Bai-He: 5 articles (05/2008 - 05/2005)
6.	Sakoda, Lori C: 5 articles (05/2008 - 05/2005)
7.	Shen, Ming-Chang: 5 articles (05/2008 - 05/2005)
8.	Gao, Yu-Tang: 5 articles (05/2008 - 05/2005)
9.	Morizane, Chigusa: 5 articles (09/2006 - 01/2003)
10.	Ueno, Hideki: 5 articles (09/2006 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Biliary Tract Neoplasms:

1.	gemcitabine FDA Link 12/01/2002 - "In conclusion, while the best available chemotherapeutic treatment for advanced biliary tract cancer remains to be determined, accumulating data from recent phase II trials suggest that single-agent gemcitabine represents an active and very well-tolerated treatment option" 05/01/2006 - "CONCLUSIONS: In single-agent therapy, gemcitabine demonstrated moderate efficacy with manageable toxicity in patients with advanced or metastatic biliary tract cancer" 01/01/2008 - "Based on favorable results reported from phase II trials, gemcitabine and S-1 are currently available as promising agents for the treatment of unresectable biliary tract cancer in Japan" 05/01/2006 - "PURPOSE: This phase II study was conducted to evaluate the efficacy and toxicity of single-agent gemcitabine in patients with advanced or metastatic biliary tract cancer" 05/01/2006 - "Phase II study of single-agent gemcitabine in patients with advanced biliary tract cancer." Get all the results and reference details, order at left...
2.	Cisplatin (Platino)FDA LinkGeneric 01/01/2008 - "A phase II trial of S-1 and cisplatin in patients with metastatic or relapsed biliary tract cancer." 08/01/2007 - "Phase II study of capecitabine and cisplatin in previously untreated advanced biliary tract cancer." 06/01/2006 - "Phase II study of gemcitabine and cisplatin in advanced biliary tract cancer." 03/15/2006 - "A Phase II study of gemcitabine and cisplatin in advanced biliary tract cancer." 02/01/2005 - "Previous small phase II trials have demonstrated that the combination of 5-fluorouracil (5FU) and cisplatin(CDDP) could have clinical activity in metastatic biliary tract cancer" Get all the results and reference details, order at left...
3.	capecitabine (Xeloda)FDA Link 08/01/2007 - "Phase II study of capecitabine and cisplatin in previously untreated advanced biliary tract cancer." 08/01/2008 - "PURPOSE: To evaluate the effects of palliative chemotherapy with gemcitabine plus capecitabine (GemCap) on patient-reported outcomes measured using clinical benefit response (CBR) and quality-of-life (QOL) measures in patients with advanced biliary tract cancer" 08/01/2007 - "CONCLUSION: The combination chemotherapy of capecitabine and cisplatin demonstrated a promising antitumor activity with mild toxicity profile in patients with advanced biliary tract cancer." 08/01/2008 - "Patient-reported outcomes of patients with advanced biliary tract cancers receiving gemcitabine plus capecitabine: a multicenter, phase II trial of the Swiss Group for Clinical Cancer Research." 03/01/2004 - "The aim was to investigate the therapeutic efficacy and tolerance of mitomycin C (MMC) in combination with gemcitabine (GEM) or capecitabine (CAPE) in previously untreated patients with advanced biliary tract cancer" Get all the results and reference details, order at left...
4.	Mitomycin (Mitomycin-C)FDA LinkGeneric 03/01/2004 - "The aim was to investigate the therapeutic efficacy and tolerance of mitomycin C (MMC) in combination with gemcitabine (GEM) or capecitabine (CAPE) in previously untreated patients with advanced biliary tract cancer" 03/01/2004 - "Mitomycin C in combination with capecitabine or biweekly high-dose gemcitabine in patients with advanced biliary tract cancer: a randomised phase II trial." 11/01/1984 - "A phase II trial of the regimen 5-fluorouracil, doxorubicin, and mitomycin C (FAM) was conducted in 17 patients with advanced or recurrent biliary tract cancer" 01/01/1998 - "To develop a specific chemotherapy modality for the perineural invasion of neural cell adhesion molecule (NCAM) positive biliary tract cancer, an anticancer drug, mitomycin C (MMC), was covalently bound to anti-NCAM monoclonal antibody (anti-NCAM MoAb) to form a conjugate using the cyanogen bromide method" 08/01/1996 - "Chemotherapy of biliary tract cancer with mitomycin-C and 5-fluorouracil biologically modulated by folinic acid" Get all the results and reference details, order at left...
5.	oxaliplatin (Eloxatin)FDA Link 01/01/2008 - "Phase II trial of S-1 in combination with oxaliplatin in previously untreated patients with recurrent or inoperable biliary tract cancer." 06/01/2006 - "CONCLUSIONS: Oxaliplatin and gemcitabine chemotherapy seems to be effective with a favorable safety profile in first-line chemotherapy of advanced biliary tract cancers." 10/09/2006 - "This phase II study was conducted to determine the efficacy and toxicity of a gemcitabine (GEM) and oxaliplatin (OX) chemotherapy protocol in patients with unresectable biliary tract cancer (BTC)" 01/01/2007 - "Chemotherapy with gemcitabine and oxaliplatin in patients with advanced biliary tract cancer: a single-institution experience." 10/09/2006 - "Outpatient chemotherapy with gemcitabine and oxaliplatin in patients with biliary tract cancer." Get all the results and reference details, order at left...
6.	imatinib (Gleevec)FDA Link 10/01/2003 - "Imatinib mesylate (STI571; Glivec)--a new approach in the treatment of biliary tract cancer?" 03/14/2006 - "The anti-proliferative effect of imatinib mesilate on biliary tract cancer cell lines Mz-ChA-2 and EGI-1 was studied in vitro by automated cell counting" 03/14/2006 - "AIM: To investigate the c-kit expression in biliary tract cancer cell lines and histological sections from patients with extrahepatic cholangiocarcinoma (CC) and to evaluate the efficacy of in vitro and in vitro treatment with imatinib mesilate" 10/01/2003 - "We conclude that imatinib alone exerts marked effects on c-kit+ biliary tract cancer cell lines only at intermediate and high concentrations, but there is a potential role of low-dose imatinib in combination with 5-FU for the treatment of biliary tract cancers." 10/01/2003 - "The aim of this study was to determine the expression of c-kit and platelet-derived growth factor (PDGF) receptors (PDGFRs) and the effects of the tyrosine kinase inhibitor imatinib +/- 5-fluorouracil (5-FU) on proliferation and apoptosis in biliary tract cancer cell lines" Get all the results and reference details, order at left...
7.	Cadherins (E-Cadherin)IBA 07/15/2002 - "Since the establishment of biliary tract cancer cell lines has been rarely reported in the literature, these newly established and well characterised biliary tract cancer cell lines would be very useful for studying the biology of biliary tract cancers, particularly those related to hypermethylation of E-cadherin gene in biliary tract cancer." 01/01/2006 - "METHODS: The expression of E-cadherin and beta-catenin proteins was examined in 4 biliary tract cancer cell lines and 49 gallbladder cancer specimens by immunofluorescent or immunohistochemical methods and Western blotting" Get all the results and reference details, order at left...
8.	Carboplatin (JM8)FDA LinkGeneric 12/01/2002 - "In view of the favorable toxicity profile and observed efficacy of gemcitabine in advanced biliary tract cancers, its evaluation in combination with other active, potentially synergistic cytotoxic drugs such as cisplatin, capecitabine, and carboplatin should be studied with an aim to improve therapeutic efficacy and survival." Get all the results and reference details, order at left...
9.	Mesylates (Mesylate)IBA 03/14/2006 - "The anti-proliferative effect of imatinib mesilate on biliary tract cancer cell lines Mz-ChA-2 and EGI-1 was studied in vitro by automated cell counting" 03/14/2006 - "AIM: To investigate the c-kit expression in biliary tract cancer cell lines and histological sections from patients with extrahepatic cholangiocarcinoma (CC) and to evaluate the efficacy of in vitro and in vitro treatment with imatinib mesilate" Get all the results and reference details, order at left...
10.	EpitopesIBA 08/01/1992 - "Coordinate evaluation of these three markers improved the sensitivity to some extent without loss of specificity for the diagnosis of pancreatic and biliary tract cancers, because of the heterogeneity of the coexpression of these epitopes" 08/01/1992 - "However, elevated serum levels of CA19-9 and Lewisa and Lewisb epitopes on moieties were restricted to pancreatic and biliary tract cancers, although adequate sensitivity was not attained" Get all the results and reference details, order at left...
146 Drugs and Important Bio-Agents and 160 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 01/01/2008 - "In this article we review previous studies and clinical trials regarding chemotherapy for unresectable biliary tract cancer, and we present guidelines for the appropriate use of chemotherapy in patients with biliary tract cancer" 01/01/2008 - "Few randomized controlled trials (RCTs) with large numbers of patients have been conducted to date in patients with biliary tract cancer, and standard chemotherapy has not been established yet" 11/01/2007 - "BACKGROUND: This study examined the effect of five systemic chemotherapy regimens on survival in patients with unresectable biliary tract cancer (BTC) as compared with the best supportive care (BSC)" 11/01/2005 - "This study investigated prognostic factors in patients with advanced biliary tract cancer receiving chemotherapy" 12/01/2003 - "Regional combined with systemic chemotherapy in unresectable biliary tract cancers: a phase II study." Get all the results and reference details, order at left...
2.	Combination Drug Therapy (Combination Chemotherapy) 10/01/2008 - "Two cases of advanced biliary tract cancer successfully treated with gemcitabine combination chemotherapy]" 09/01/2006 - "CONCLUSIONS: Combination chemotherapy of UFT and doxorubicin was well tolerated and showed preliminary moderate activity against advanced biliary tract cancer" 03/15/2006 - "BACKGROUND: The authors performed a Phase II study of combination chemotherapy with gemcitabine and cisplatin in patients with inoperable biliary tract cancer to evaluate efficacy and toxicity of this combination" 08/01/2007 - "CONCLUSION: The combination chemotherapy of capecitabine and cisplatin demonstrated a promising antitumor activity with mild toxicity profile in patients with advanced biliary tract cancer." 06/01/2006 - "Gemcitabine and oxaliplatin combination chemotherapy in advanced biliary tract cancers." Get all the results and reference details, order at left...
3.	Cholecystectomy 11/01/1990 - "The aim of this study was to correlate extrahepatic biliary tract cancer mortality and cholecystectomy rates of previous years during the last decade in our country" 01/01/1994 - "As an artificial factor, the effect of the prevalence of cholecystectomy on biliary tract cancer must be considered" 05/01/1993 - "Prophylactic cholecystectomy is recommended in patients with this anomalous junction without bile duct dilatation or a malignant lesion in the gallbladder, because of the high incidence of cancer of the biliary tract." 01/01/1985 - "Relatively high incidence rates of biliary tract cancer in Slovakia as well as in whole Czechoslovakia, in comparison with other countries or areas of Europe, could be related to the excessive prevalence of gallstones and high number of surgical interventions upon biliary tract in this country while the decreasing incidence rates in women coincided with elevated number of cholecystectomies" 05/01/2002 - "Given the risk of biliary tract cancer in PSC in the face of the benign nature of most gallbladder polyps in the general population, our aim was to determine the prevalence of gallbladder cancer in PSC patients with a gallbladder mass who had undergone cholecystectomy" Get all the results and reference details, order at left...
4.	Palliative Care (Palliative Medicine) 01/01/2006 - "Palliative therapy in patients with biliary tract cancer]" 10/01/1992 - "The interest of surgical prostheses in the palliative treatment of biliary tract cancer is well established, on the basis of their good tolerance, the more than 15 year follow up experience and the number of patients operated upon" 03/01/2007 - "Here we examine clinical trials designed for locally advanced and metastatic biliary tract cancer and review the existing data supporting palliative therapy with gemcitabine alone or in association with other drugs." 02/01/2001 - "CONCLUSIONS: Two-weekly high-dose gemcitabine seems to represent a potentially effective, safe and well-tolerated regimen for the palliative treatment of patients with advanced biliary tract cancer." Get all the results and reference details, order at left...
5.	Absorbable Gelatin Sponge 01/01/2000 - "Clinical Study: transcatheter portal embolization of the right portal branch was performed in 13 patients with cancer of the biliary tract and 3 patients with hepatocellular carcinoma before (extended) right lobectomy, using Gelfoam powder and thrombin" Get all the results and reference details, order at left...
21 Therapies and Procedures and 72 more articles analyzed in the Research Interface, order at left...

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License details >>

Price:

$490.00 access via web interface, 1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m", 1 year subscription

Proceed to Checkout >>