beta-Glucosidase

An exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of GLUCOSE.

Also Known As:

Amygdalase; Cellobiase; Emulsion beta-D-Glucosidase; Gentiobiase; Emulsion beta D Glucosidase; beta Glucosidase; beta-D-Glucosidase, Emulsion; Cellobiases; beta-D-Glucoside glucohydrolase

Networked: 217 relevant articles (3 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Glycoside Hydrolases: 871
      - Glucosidases: 1733
        Cellulases: 38
        beta-Glucosidase: 217
        cyanogenic beta-glucosidase: 9
        4-methylumbelliferyl-beta-glucosidase: 4
        naringinase: 2
        avenacosidase: 1
        PerT-GUS: 1
        2,4-dihydroxy - 7-methoxy-1,4-benzoxazin-3-one glucoside beta-glucosidase
        6-ethanoylamino-4-methylumbelliferyl-beta-glucosidase
        Agrobacterium rhizogenes RolB protein
        ajmalicine synthetase system
        amygdalin beta(1-6)glucosidase
        Arabidopsis BGLC1 protein
        Arabidopsis BGLC3 protein
        Arabidopsis BGLU42 protein
        Arabidopsis PYK10 protein
        Arabidopsis SFR2 protein
        bacteria celC protein
        Cucurbita pepo SLW3 protein
        cytokinin-beta-glucosidase
        Erwinia chrysanthemi BgxA protein
        furostanol glycoside 26-O-beta-glucosidase
        Gaeumannomyces graminis avenacinase protein
        ginsenoside-beta-glucosidase
        human GBA3 protein
        linustatinase
        mouse beta-glucosidase 2
        Nicotiana tabacum Tag 1 protein
        Novozym 188
        Olea europaea OLE9 protein
        prunasin hydrolase
        Pyrococcus furiosus CelB protein
        rutinase
        Sorghum Dhr1 protein
        Tenebrio molitor betaGly protein
        Thermus nonproteolyticus beta-glycosidase
        XynB xylanase
        Z glucanase
        zebrafish GBA2 protein

Experts

1.	Ogawa, Seiichiro: 3 articles (05/2009 - 08/2004)
2.	Suzuki, Yoshiyuki: 3 articles (05/2009 - 08/2004)
3.	Giugliani, Roberto: 3 articles (12/2005 - 05/2004)
4.	Michelin, Kristiane: 3 articles (12/2005 - 05/2004)
5.	Wajner, Alessandro: 3 articles (12/2005 - 05/2004)
6.	Ciana, Giovanni: 2 articles (05/2021 - 08/2009)
7.	Dardis, Andrea: 2 articles (05/2021 - 08/2009)
8.	Fuller, Maria: 2 articles (04/2008 - 11/2005)
9.	Hopwood, John J: 2 articles (04/2008 - 11/2005)
10.	Lovejoy, Melanie: 2 articles (04/2008 - 11/2005)

Related Diseases

1.	Gaucher Disease (Gaucher's Disease) 09/01/1981 - "An improved fluorometric leukocyte beta-glucosidase assay for Gaucher's disease." 05/01/2004 - "Biochemical study on beta-glucosidase in individuals with Gaucher's disease and normal subjects." 03/01/2001 - "Our study demonstrates the functional consequences of the identified human beta-glucosidase mutations (T134P, S364N, G377S, P391L, and G325W) and provide evidence for the molecular and biochemical basis of Gaucher disease, among patients of Spanish ancestry." 06/11/1986 - "In vitro studies on the pathobiology of such macrophages whose beta-glucosidase activity has been reduced may be useful toward understanding the pathogenesis of Gaucher disease." 05/24/2021 - "Gaucher disease (GD) is an autosomal recessive lysosomal disorder due to beta-glucosidase gene (GBA) mutations. "
2.	Periodontitis 01/01/1992 - "The total activities (as units of enzyme activity per sample) of alpha-L-fucosidase, sialidase, beta-N-acetylglucosaminidase, beta-galactosidase, beta-glucosidase and alpha-glucosidase were significantly greater in the periodontitis group. "
3.	Coronary Disease (Coronary Heart Disease) 01/01/1991 - "They recommend using the index of red blood cell fatty acid unsaturation as the characteristic, indicating liability to coronary disease; lysosomal beta-glucosidase activity for assessment of the severity of myocardial injury; simultaneous measurements of hydroxyproline and uric acid for estimation of the completeness of cicatrization and of the myocardial injury severity; and the fatty acid unsaturation index and hydroxyproline level for the assessment of the efficacy of rehabilitation measures."
4.	Cicatrix (Scar) 01/01/1991 - "They recommend using the index of red blood cell fatty acid unsaturation as the characteristic, indicating liability to coronary disease; lysosomal beta-glucosidase activity for assessment of the severity of myocardial injury; simultaneous measurements of hydroxyproline and uric acid for estimation of the completeness of cicatrization and of the myocardial injury severity; and the fatty acid unsaturation index and hydroxyproline level for the assessment of the efficacy of rehabilitation measures."
5.	Neoplasms (Cancer) 01/01/2019 - "Only compounds 5, 8, 10, 13, and 14 exhibited a higher activity as cellobiase while compounds 2 and 5 showed a highly enzymatic effect on tumor cells. " 01/01/2019 - "The new fluorinated modified rhodanines 2-16 were evaluated as enzymatic probes for cellobiase activity produced by fungi and as CDK2 inhibitors of tumor cells. " 02/15/1980 - "The beta-glucosidase content of cancer tissues is low compared to that of normal liver and small intestine. " 01/01/2019 - "Various N, S and O-alkyl derivatives of fluorine-substituted rhodanines were prepared via a simple method and used as enzymatic probes for cellobiase activity produced by fungi and CDK2 inhibitors for tumor cells. " 01/01/2019 - "Novel fluorine substituted N-alkyl, S-alkyl and amino-rhodanines were obtained via Hydroxy methylation, Mannich reactions, chlorination and amination of 5-(4'-fluorophenylene)-2-thioxothiazolidin- 4-one, and the enzymatic effects of cellobiase produced by fungi and /or CDK2 inhibition of tumor cells were evaluated. "

Related Drugs and Biologics

1.	beta-Galactosidase (Lactaid)
2.	Acetylglucosaminidase (NAGase)
3.	Enzymes
4.	alpha-Glucosidases (Acid Maltase)
5.	alpha-L-Fucosidase (Fucosidase)
6.	Neuraminidase (Sialidase)
7.	Uric Acid (Urate)
8.	Hydroxyproline (4 Hydroxyproline)
9.	Fatty Acids (Saturated Fatty Acids)
10.	Glucuronidase

Related Therapies and Procedures

1.	Therapeutics
2.	Enzyme Replacement Therapy
3.	Vegetarian Diet (Vegetarianism)
4.	Nephrectomy