Benzylamines (Phenylmethylamine)

Toluenes in which one hydrogen of the methyl group is substituted by an amino group. Permitted are any substituents on the benzene ring or the amino group.

Also Known As:

Phenylmethylamine; alpha Aminotoluene; alpha-Aminotoluene

Networked: 10 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Benzylamines: 10
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Benzylamines: 10
        plerixafor: 902
        ximelagatran: 239
        Pargyline: 171
        safinamide: 158
        KN 93: 151
        dapoxetine: 148
        DSP 4: 105
        MYK-461: 103
        melagatran: 79
        GW 3965: 76
        benzylamine: 73
        butenafine: 46
        spautin-1: 23
        dibenzylamine: 22
        ciramadol: 19
        (2-(6-fluoro-1H-indol-3-yl)-ethyl)-(3-(2,2,3,3-tetrafluoropropoxy)benzyl)amine: 17
        N-methylbenzylamine: 14
        N-benzyl-N,N-dimethylamine: 13
        2-(aminomethyl)phenol: 10
        teclozan: 10
        benzyl-(1-amino-3-chloro-2-propanol): 8
        2-(4-chloro-2,5-dimethoxyphenyl)-N-((2-methoxyphenyl)methyl)ethanamine: 7
        N-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yloxy)ethyl)-3-(cyclopent-1-enyl)benzylamine: 6
        N-(3-(aminomethyl)benzyl)acetamidine: 6
        KN 92: 5
        ezlopitant: 4
        N,N-dipropyl-N'-(4-((((1H-imidazol-2-yl)methyl)((1-methyl-1H-imidazol-2-yl) methyl)amino)methyl)benzyl)-N'-methylbutane-1,4-diamine: 4
        quinpramine: 4
        SR 121566: 4
        1-(1H-1,2,4-triazole)-2-(2,4-difluorophenyl)-3-(N-methyl-N-(4-iodobenzyl)amino)-2-propanol: 3
        4-methoxybenzylamine: 3
        AP 2238: 3
        BC-1215: 3
        SR 121787: 3
        (2-fluorobenzyl)-(2-methyl-2-phenyl-2H-chromen-6-yl-amine): 2
        Bumepamine: 2
        CGP 52432: 2
        KYT-36: 2
        N-benzyl-N-hydroxy-5-phenylpentamide: 2
        NB 598: 2
        SDZ GPI 562: 2
        vanillylamine: 2
        1,4-bis(aminomethyl)-2,3,5,6-tetrafluorobenzene: 1
        2,3-dichloro-alpha-methylbenzylamine: 1
        2,5-dimethoxybenzylamine: 1
        25D-NBOMe: 1
        3-(triphenylmethylaminomethyl)pyridine: 1
        4-((3,5-dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid: 1
        FR 194738: 1
        LY2196044: 1
        MK 251: 1
        N,N-dilactitol-3,5-bis(trifluoromethyl)benzylamine: 1
        N-(3-(4-morpholino)propyl)-N-methyl-2-hydroxy-5-iodo-3-methylbenzylamine: 1
        NIP 502: 1
        pelargonic acid vanillylamide: 1
        SLL-039: 1
        vetrabutin chlorhydrate: 1
        ZL006 compound: 1
        (2'-((cyclopropanecarbonylethylamino)methyl)-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)acetic acid
        (2-((2-((dimethylamino)methyl)-4-iodophenyl)thio)phenyl)methanol
        (4-(4-((benzyl(2-methyl-3-((methylsulfonyl)amino)phenyl)amino)methyl)phenoxy)phenoxy)acetic acid
        (5-(2-((benzoyloxycarbonylethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid
        (5-(4-(((2,4-difluorobenzyl)(2-methyl-3-((methylsulfonyl)amino)phenyl)amino)methyl)phenoxy)-2-fluorophenoxy)acetic acid
        (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile
        (S)-2-(4-(3-(piperidin-1-yl)propoxy)benzylamino)propaneamide
        1,13-bis(4'-(4H-chromen-4-on-2-yl)phenyl)-N-(benzyl)-1,4,10,13-tetraoxa-7-azatridecane
        1-(2-(5-fluoro-2-methoxyphenyl)cyclopropyl)-N-(2-methoxybenzyl)methanamine
        1-(benzylamino)ethaniminium
        1-(isopropylamino)-3-(5-((isopropylamino)methyl)-2-methoxyphenoxy)propan-2-ol
        1-(tert-butylamino)-3-(5-tert-butylaminomethyl-2-methoxyphenoxy)propan-2-ol
        1-adamantyl (5-bromo-2-methoxybenzyl) amine
        1-amino-3',4'-dichlorobenzylphosphonic acid
        2,4-dimethoxybenzylamine
        2,6-dibutylbenzylamine
        2-((2-amino-4-chloro-5-fluorophenyl)thio)-N,N-dimethylbenzenemethanamine
        2-((4-fluorobenzylamino)methyl)chroman-7-ol
        2-((dimethylamino)methyl)phenylgold(III) dichloride
        2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid
        2-(2-(dimethylaminomethyl)benzyl)-5-iodophenylamine
        2-(3-benzylamino-2-oxo-1,2-dihydropyridin-1-yl)-N-(3,4-dichlorobenzyl)acetamide
        2-(4-((benzylmethylamino)methyl)benzylidene)-6-(5-diethylaminopentyloxy)-3,4-dihydro-2H-naphthalen-1-one
        2-(4-((benzylmethylamino)methyl)benzylidene)-6-(5-piperidin-1-yl-pentyloxy)-3,4-dihydro-2H-naphthalen-1-one
        2-(5-(3-chlorobenzylamino)pentyl)isoindoline-1,3-dione
        2-(5-(4-fluorobenzylamino)pentyl)isoindoline-1,3-dione
        2-(bis(4-fluorophenyl)methyl)-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol
        2-(N,N-dibenzylamino)butane-1,3-diol
        2-(N-(2-aminoethyl)-N-(2,4,5-trichlorobenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine
        2-acetyl benzylamine
        2-bromo-3,3-dimethyl-N-N-(alpha-alpha-dimethylbenzyl) butyramide
        3,4-bis(tetradecyloxy)benzylamine
        3,4-dimethoxybenzylamine
        3-nitrobenzylamine
        4,5-dimethoxy-2-mercaptobenzylamine
        4-(((6-bromo-1H-indazol-4-yl)amino)methyl)phenol
        4-(N-2-chloroethyl-N-(methyl)amino)benzylmethylamine
        4-benzylaminesulfonic acid
        4-dimethylaminobenzylamine
        4-dimethylaminomethylbenzylamine
        4-hydroxy 3-methoxybenzylamine
        4-hydroxybenzylamine

Experts

1.	Cämmerer, Simon B: 1 article (01/2022)
2.	Dos Santos, Mayara Roncaglia: 1 article (01/2022)
3.	Rodrigues, Juliany Cola Fernandes: 1 article (01/2022)
4.	Souza, Gabrielle Frizzo: 1 article (01/2022)
5.	Visbal, Gonzalo: 1 article (01/2022)
6.	de Macedo-Silva, Sara Teixeira: 1 article (01/2022)
7.	de Souza, Wanderley: 1 article (01/2022)
8.	Akıncıoğlu, Akın: 1 article (10/2021)
9.	Akıncıoğlu, Hülya: 1 article (10/2021)
10.	Göksu, Süleyman: 1 article (10/2021)

Related Diseases

1.	Tuberculosis (Tuberculoses) 01/01/1996 - "This, combined with indirect effects including enhancement of lysozyme levels in bronchial secretions and levels of rifampicin in lung tissue and sputum, and possibly clearance of bacilli-laden mucus from cavities and bronchi, suggests a potentially useful adjunctive function for these agents in the therapy of tuberculosis, and adds credibility to early reports of the beneficial effect of benzylamines in this disease."
2.	Infections 04/01/2001 - "The topical allylamines and benzylamines have been especially effective in treating these infections because of their in vitro fungicidal activity and short treatment duration. "
3.	Neoplasms (Cancer) 02/01/2009 - "Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies."
4.	Tinea Capitis 11/01/2013 - "The most common organisms causing SCFI are dermatophytes, especially Trichophyton spp. With the exception of onchomycosis and tinea capitis, most cases of SCFIs are amenable to properly selected topical antifungal therapy used over an adequate period of time.<br><br> A variety of topical antifungal agents are available for the treatment of SCFIs, and they encompass a few major chemical classes: the polyenes (ie, nystatin), imidazoles (ie, ketoconazole, econazole, oxiconazole, etc), allylamines (ie, naftifine, terbinafine), benzylamines (ie, butenafine), and hydroxypyridones (ie, ciclopirox). "
5.	Prostatic Neoplasms (Prostate Cancer) 07/05/2021 - "Tetrahydropyrans 3 require a lower dissociative force peak than cyclohexane analogs 2. Enantiomeric benzylamines 3a and cyclohexylmethylamines 3b were able to inhibit the growth of the androgen negative human prostate cancer cell line DU145. "

Related Drugs and Biologics

1.	Rifampin (Rifampicin)
2.	Muramidase (Lysozyme)
3.	Urea (Carbamide)
4.	Thiophenes
5.	Tea
6.	Salicylamides
7.	Polyenes
8.	Nystatin (Mycostatin)
9.	Minoxidil (Rogaine)
10.	Ketoconazole (Nizoral)

Related Therapies and Procedures

1.	Therapeutics
2.	Duration of Therapy