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Benzopyrene Hydroxylase

A drug-metabolizing, cytochrome P-448 (P-450) enzyme which catalyzes the hydroxylation of benzopyrene to 3-hydroxybenzopyrene in the presence of reduced flavoprotein and molecular oxygen. Also acts on certain anthracene derivatives. An aspect of EC 1.14.14.1.
Also Known As:
Benzo(a)pyrene Hydroxylase; Benzo(a)pyrene Monooxygenase; Benzopyrene 3 Monooxygenase; Hydroxylase, Benzopyrene; Benzopyrene-3-Monooxygenase
Networked: 34 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ishida, Yuji: 1 article (05/2009)
2. Uno, Shigeyuki: 1 article (05/2009)
3. Endo, Kaori: 1 article (05/2009)
4. Yoshizato, Katsutoshi: 1 article (05/2009)
5. Tateno, Chise: 1 article (05/2009)
6. Nebert, Daniel W: 1 article (05/2009)
7. Makishima, Makoto: 1 article (05/2009)
8. Ueng, T H: 1 article (09/2000)
9. Chen, R M: 1 article (09/2000)
10. Chou, M W: 1 article (09/2000)

Related Diseases

1. Neoplasms (Cancer)
2. Lung Neoplasms (Lung Cancer)
3. Experimental Liver Neoplasms
4. Breast Neoplasms (Breast Cancer)
5. Hepatocellular Carcinoma (Hepatoma)

Related Drugs and Biologics

1. Cytochrome P-450 Enzyme System (Cytochrome P450)
2. Enzymes
3. Cytochromes c (Cytochrome c)
4. NADP (NADPH)
5. NADPH Oxidase (NAD(P)H oxidase)
6. ferricyanide reductase
7. diphenyl (biphenyl)
8. hexacyanoferrate III (ferricyanide)
9. Cytochrome P-450 CYP1A1 (CYP1A1)
10. Cytochromes