Benzaldehydes

Compounds that consist of a benzene ring with a formyl group. They occur naturally in the seeds of many fruits and are used as FLAVORING AGENTS and fragrances, as well as precursors in pharmaceutical and plastics manufacturing.

Networked: 9 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Johansen, Matt D: 1 article (01/2022)
2.	Kremer, Laurent: 1 article (01/2022)
3.	Kumar, Sumit: 1 article (01/2022)
4.	Kumar, Vipan: 1 article (01/2022)
5.	Preeti,: 1 article (01/2022)
6.	Sharma, Bharvi: 1 article (01/2022)
7.	Hu, Jun-Hao: 1 article (01/2017)
8.	Hu, Yan: 1 article (01/2017)
9.	Liu, Xi-Hai: 1 article (01/2017)
10.	Park, Hojoon: 1 article (01/2017)

Related Diseases

1.	Tuberculosis (Tuberculoses) 01/01/2022 - "Evaluation results revealed that the inclusion of isoniazid core into 1H-1,2,3-triazole tethered isatin-benzaldehydes improved the antimycobacterial activity on tuberculosis mc2 6230 strain and significantly reduced the cytotoxicity against Vero cells. "
2.	Edema (Dropsy) 05/01/2006 - "The synthesis of 1,3-diaryl propen-1-ones (chalcones) by the Claisen-Schmidt condensation between acetophenones and benzaldehydes in potassium hydroxide/methanol medium at room temperature yielded: 1-(4-nitrophenyl)-3-(2,4,6-trimethoxyphenyl)propen-1-one (3a), 1-(4-nitrophenyl)-3-(3-bromophenyl)propen-1one (3b), 1-(4-methoxyphenyl)-3-(3-bromophenyl)propen-1-one (3c), 1-(4-methoxyphenyl)-3-(2,4,6-trimethoxyphenyl)propen-1-one (3d), 1-(2,4-dihydroxyphenyl)-3-(phenyl)propen-1-one (3e), 1-(4-nitrophenyl)-3-(4-chlorophenyl)propen-1-one (3f) which were evaluated for anti-inflammatory activity at doses of 20, 40 and 80mg/kg. The compounds were found to be effective inhibitors of carrageenan-induced rat paw edema in Wistar rats and this activity was dose dependent and increased between the third and fourth hour. "
3.	Neoplasms (Cancer) 01/01/2014 - "Compared to current cancer targeted therapeutic drugs, chalcones have the advantages of being inexpensive, easily available and less toxic; the ease of synthesis of chalcones from substituted benzaldehydes and acetophenones also makes them an attractive drug scaffold. " 06/23/2014 - "Antiproliferative activity against four cancer cell lines (e.g., HuCCA-1, HepG2, A549 and MOLT-3) revealed that many substituted triazole analogs of benzoates (20, 29) and benzaldehydes (30, 32) exhibited anticancer activity against all of the tested cancer cell lines in which the ester analog 20 was shown to be the most potent compound against HuCCA-1 (IC50 = 0.63 μM) and A549 (IC50 = 0.57 μM) cell lines. "
4.	Dehydration (Water Stress) 03/15/2007 - "A conjugate addition-aldol-dehydration reaction of alpha,beta-unsaturated aldehydes with 2-N-protected amino benzaldehydes has been developed. " 07/01/1992 - "Substituted benzaldehydes (12C79 and 589C80) that stabilize oxyhaemoglobin also protect sickle cells against calcium-mediated dehydration." 03/15/2007 - "Chiral Diphenylprolinol TES ether promoted conjugate addition-aldol-dehydration reactions between alpha,beta-unsaturated aldehydes and 2-N-protected amino benzaldehydes."
5.	Poisoning 01/01/2017 - "The transient directing groups formed in situ via imine linkage can override other coordinating functional groups capable of directing C-H activation or catalyst poisoning, significantly expanding the scope for metal-catalyzed C-H functionalization of benzaldehydes. "

Related Drugs and Biologics

1.	Chalcones
2.	Acetophenones
3.	Isoniazid (Ftivazide)
4.	Isatin
5.	Carrageenan
6.	Methanol (Carbinol)
7.	potassium hydroxide
8.	Coordination Complexes
9.	Zinc
10.	Triazoles