Basal Ganglia Diseases (Basal Ganglia Disease)

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179 relevant articles (4 outcomes, 15 trials/studies) found for this Disease

Description: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Also Known As:

Basal Ganglia Disease; Extrapyramidal Disorder; Basal Ganglia Disorders; Lenticulostriate Disorders; Basal Ganglia Disorder; Lenticulostriate Disorder; Extrapyramidal Disorders

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3338

Central Nervous System Diseases: 916

Brain Diseases: 1100

Basal Ganglia Diseases: 179

Parkinsonian Disorders: 4660

Huntington Disease: 3109

Hepatolenticular Degeneration: 2024

Tourette Syndrome: 837

Neuroleptic Malignant Syndrome: 758

Multiple System Atrophy: 620

Progressive Supranuclear Palsy: 458

Dystonia Musculorum Deformans: 152

Pantothenate Kinase-Associated Neurodegeneration: 116

Meige Syndrome: 38

Chorea Gravidarum: 16

Basal Ganglia Cerebrovascular Disease: 2

Related Diseases

1.	Weight Gain
2.	Parkinson Disease (Parkinson's Disease)
3.	Nervous System Diseases (Neurological Disorders)
4.	Chorea (Rheumatic Chorea)
5.	Dyskinesias (Dyskinesia)
45 Diseases and 65 more articles analyzed in the Research Interface, order at left...

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Basal Ganglia Diseases:

1.	Amantadine (Aman)FDA LinkGeneric 07/01/1977 - "A controlled trial of amantadine in drug-induced extrapyramidal disorders." 05/01/1976 - "A controlled trial of amantadine in drug-induced extrapyramidal disorders." 05/01/1987 - "The subjects neither complained of nor demonstrated memory impairment while taking amantadine, which is believed to exert its pharmacological effects upon extrapyramidal disorders via dopaminergic mechanisms and does not appear to be associated with memory impairment" 04/01/1981 - "Amantadine is useful for the prevention and treatment of influenza A and for the treatment of Parkinson's disease and drug-induced extrapyramidal disorders" 01/01/1991 - "The antagonism between amantadine and chlorpromazine on brain amines may explain the therapeutic efficacy of amantadine in modulating chlorpromazine-induced extrapyramidal disorders." Get all the results and reference details, order at left...
2.	FlunarizineIBA 01/01/1988 - "Long-term administration of flunarizine should be avoided particularly in the elderly and in patients with extrapyramidal disorders." 10/01/2006 - "6) Flunarizine also has documented efficacy, but this "hidden neuroleptic" can cause extrapyramidal disorders and weight gain" 01/01/1989 - "In addition, the large number of conditions susceptible to being corrected by CA is impressive: epilepsy, pain, dystonia, dyskinesia, psychiatric conditions, etc. Other papers are disconcerting that report extrapyramidal disorders induced by flunarizine and cinnarizine in the elderly, whereas nicardipine does not produce such side effects and may even alleviate some parkinsonian symptoms" Get all the results and reference details, order at left...
3.	Chlorpromazine (Thorazine)FDA LinkGeneric 02/09/1996 - "These data suggest that chlorpromazine may increase iron uptake by neurons, and may be involved in the development of tardive dyskinesia and other extrapyramidal disorders." 01/01/1991 - "The antagonism between amantadine and chlorpromazine on brain amines may explain the therapeutic efficacy of amantadine in modulating chlorpromazine-induced extrapyramidal disorders." Get all the results and reference details, order at left...
4.	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 06/01/2002 - "One group of receptors that holds much promise for several basal ganglia disorders is the metabotropic glutamate receptors" Get all the results and reference details, order at left...
5.	Reserpine (Serpasil)FDA Link 07/01/1957 - "Good results obtained with ACTH in extrapyramidal disorders caused by reserpine.]" Get all the results and reference details, order at left...
6.	AminesIBA 01/01/1991 - "The antagonism between amantadine and chlorpromazine on brain amines may explain the therapeutic efficacy of amantadine in modulating chlorpromazine-induced extrapyramidal disorders." Get all the results and reference details, order at left...
7.	Adrenocorticotropic Hormone (ACTH)FDA Link 07/01/1957 - "Good results obtained with ACTH in extrapyramidal disorders caused by reserpine.]" Get all the results and reference details, order at left...
8.	Haloperidol (Haldol)FDA LinkGeneric 01/01/1981 - "A use of haloperidol in increasing dosages (from 1 mg/kg up to 12 mg/kg) leads to an appearance of extrapyramidal disorders, a damage of the nervous system and changed forms of compensation" 02/01/2004 - "Mathematical modeling showed that affinity of the ligand for M4 receptors positively affects its ability to correct extrapyramidal disorders (catatonic syndrome) produced by haloperidol, while affinity for M2 receptors had a negative effect on this characteristic." 10/01/2005 - "In clinical trials, daily doses of aripiprazole, ranging from 15 mg to 30 mg, provoked fewer extrapyramidal disorders than haloperidol 10 mg/day" 01/01/1977 - "Influence of extrapyramidal disorders induced by haloperidol on phenamine stereotypy and the effects of schizophrenic patients' serum (experimental study)]" 01/01/2005 - "Extrapyramidal disorder and hyperkinesias, the most commonly reported adverse events with antipsychotic use, occurred less frequently with risperidone than haloperidol" Get all the results and reference details, order at left...
9.	Risperidone (Risperdal Consta)FDA Link 04/01/2006 - "Extrapyramidal disorders were infrequent during short-term trials, but their incidence reached about 25% after a year of risperidone treatment" 01/01/2004 - "The overall incidence of extrapyramidal disorders in clinical trials was low (< or= 10%) with similar, yet minimal, changes in extrapyramidal symptom severity between patients treated with long-acting risperidone, oral risperidone or placebo" 10/01/2005 - "In contrast, there was no difference in the frequency of extrapyramidal disorders with aripiprazole 20 or 30 mg/day and risperidone (6 mg)" 01/01/2005 - "Extrapyramidal disorder and hyperkinesias, the most commonly reported adverse events with antipsychotic use, occurred less frequently with risperidone than haloperidol" 01/01/2006 - "Overall risperidone caused more weight gain than haloperidol but less extrapyramidal disorder and comparable sedation" Get all the results and reference details, order at left...
10.	Dopamine (Intropin)FDA LinkGeneric 01/01/1997 - "However, the behaviors affected by basal ganglia disorders can be in part explained by the integrative nature of the dopamine system and its links to motor, limbic, and association areas of the striatum and cortex." 09/01/1991 - "The data suggest an increase in dopamine turnover particularly in brain areas associated with motor function and posture which may account for tricyclic-antidepressant-induced extrapyramidal disorders" 01/01/1980 - "Changing concepts of nigral dopamine system function within the basal ganglia: relevance to extrapyramidal disorders." 11/01/1965 - "Dopamine and basal ganglia disorders." 01/01/1961 - "Dopamine and basal ganglia diseases." Get all the results and reference details, order at left...
132 Drugs and Important Bio-Agents and 170 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Pallidotomy 07/01/1995 - "Pallidotomy for basal ganglia disorders]" 01/01/1985 - "The results of stereotactic pallidotomy in 37 patients with extrapyramidal disorders are presented" 01/01/1985 - "Stereotactic pallidotomy in extrapyramidal disorders." Get all the results and reference details, order at left...
2.	Drug Therapy (Chemotherapy) 07/01/1998 - "A consequence of such an experience is that magnetic resonance imaging or computed tomography scans should be made of every patient with uncommon extrapyramidal disorders, particularly if they do not respond to drug therapy." 01/01/1961 - "Role of central mediators in experimental production and drug therapy of some extrapyramidal disorders.]" Get all the results and reference details, order at left...
3.	Transplants (Transplant) 05/01/2000 - "The invited speakers were chosen to be wide ranging and contributions encompassed evolution, circuitry and receptors of the basal ganglia, striatal remodelling after dopamine loss, striatal functioning in humans with Huntington's disease and in primate models after midbrain fetal transplants, and the genetics of basal ganglia disorders" Get all the results and reference details, order at left...
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