Autonomic Nervous System Diseases (Dysautonomia)

255  relevant articles (10 outcomes, 19 trials/studies) found for this Disease

Dysautonomia; Pure Autonomic Failure; Disorders of the Autonomic Nervous System; ANS (Autonomic Nervous System) Diseases; ANS Diseases; Autonomic Central Nervous System Diseases; Autonomic Diseases; Autonomic Nervous System Disorders; Autonomic Peripheral Nervous System Diseases; Segmental Autonomic Dysfunction; ANS Disease; Autonomic Disease; Autonomic Dysfunction, Segmental; Autonomic Dysfunctions, Segmental; Autonomic Failure, Pure; Dysautonomias; Pure Autonomic Failures; Segmental Autonomic Dysfunctions; Central Autonomic Nervous System Diseases; Nervous System Diseases, Autonomic; Nervous System Diseases, Parasympathetic; Nervous System Diseases, Sympathetic; Parasympathetic Nervous System Diseases; Peripheral Autonomic Nervous System Diseases; Sympathetic Nervous System Diseases

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Multiple System Atrophy
2.	Parkinson Disease (Parkinson's Disease)
3.	Orthostatic Hypotension (Postural Hypotension)
4.	Hypovolemia
5.	Dystonia (Limb Dystonia)
119 Diseases and 157 more articles analyzed in the Research Interface, order at left...

Experts

1.	Young, Tim M: 2 articles (05/2006 - 06/2004)
2.	Mathias, Christopher J: 2 articles (05/2006 - 06/2004)
3.	Acampa, M: 2 articles (09/2005 - 02/2004)
4.	Hayek, Y: 2 articles (09/2005 - 02/2004)
5.	Guideri, F: 2 articles (09/2005 - 02/2004)
6.	Zappella, M: 2 articles (09/2005 - 02/2004)
7.	Braune, S: 2 articles (08/2001 - 05/2000)
8.	Sato, Takuya: 1 article (04/2008)
9.	Carmona, Gilberto: 1 article (04/2008)
10.	Imrich, Richard: 1 article (04/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Autonomic Nervous System Diseases:

1.	Norepinephrine (Noradrenaline)FDA LinkGeneric 06/01/2004 - "In one pure autonomic failure patient, the infusion of norepinephrine induced potentiation of the responses at rest and a decrease in the expected changes after provocative tests" 01/01/2003 - "Norepinephrine and heart rate variability: a marker of dysautonomia in chronic Chagas cardiopathy." 12/10/2001 - "Reduced plasma noradrenaline levels and enhanced pressure response to noradrenaline infusion were compatible with a diagnosis of acute pan-dysautonomia" 06/01/1998 - "By combining direct sampling of internal jugular venous blood with a noradrenaline isotope dilution method, for examining neuronal transmitter release, and microneurographic nerve recording, we were able to quantify the release of central nervous system noradrenaline and its metabolites and investigate their association with efferent sympathetic nervous outflow in healthy subjects and patients with pure autonomic failure" 07/01/1997 - "In patients with pure autonomic failure, jugular overflow of norepinephrine and metabolites was not reduced, indicating brain neurons and not cerebrovascular sympathetics was the source" Get all the results and reference details, order at left...
2.	ReninIBA 11/01/1997 - "Identification of a renin threshold and its relationship to salt intake in a patient with pure autonomic failure." 11/01/1997 - "Similarly, plasma norepinephrine (92+/-15 pg/mL) and plasma renin activity (0.3+/-0.05 ng/mL per hour) were very low in the subset of patients with pure autonomic failure and supine hypertension (mean systolic/diastolic pressure, 177 +/- 6/108 +/- 2 mm Hg, range 167/97 to 219/121)" 03/01/2002 - "This is due to residual sympathetic tone in patients with multiple system atrophy (Shy-Drager syndrome), but the cause is not known in patients with pure autonomic failure, who have increased vascular resistance despite very low levels or plasma norepinephrine and renin activity" 01/01/1997 - "Recent studies of the hyperadrenergic (elevated plasma norepinephrine) subgroup of orthostatic intolerance is documenting a clinical spectrum including attenuated plasma renin activity and aldosterone, reduced supine blood volume coupled with dynamic orthostatic hypovolemia, elevated plasma norepinephrine and epinephrine, impaired clearance of norepinephrine from the circulation and evidence of partial dysautonomia" Get all the results and reference details, order at left...
3.	Epinephrine (Adrenaline)FDA LinkGeneric 05/01/2003 - "To test for sympathetic and adrenomedullary inhibition of leptin release, we studied clinical models of high sympathetic tone, heart failure, and essential hypertension, in which lowered plasma leptin levels might have been expected but were not found; a model of low sympathetic activity, pure autonomic failure, in which plasma leptin level was normal (6.1+/-1.2 vs 12.8+/-3.1 ng/mL in healthy subjects); and a clinical model of reduced epinephrine secretion, healthy aging, in which plasma leptin level again was normal (5.7+/-1.1 ng/mL vs 4.0+/-0.9 ng/mL in men >60 years and <35 years, respectively)" 01/01/1997 - "Recent studies of the hyperadrenergic (elevated plasma norepinephrine) subgroup of orthostatic intolerance is documenting a clinical spectrum including attenuated plasma renin activity and aldosterone, reduced supine blood volume coupled with dynamic orthostatic hypovolemia, elevated plasma norepinephrine and epinephrine, impaired clearance of norepinephrine from the circulation and evidence of partial dysautonomia" Get all the results and reference details, order at left...
4.	AldosteroneIBA 01/01/1997 - "Recent studies of the hyperadrenergic (elevated plasma norepinephrine) subgroup of orthostatic intolerance is documenting a clinical spectrum including attenuated plasma renin activity and aldosterone, reduced supine blood volume coupled with dynamic orthostatic hypovolemia, elevated plasma norepinephrine and epinephrine, impaired clearance of norepinephrine from the circulation and evidence of partial dysautonomia" Get all the results and reference details, order at left...
5.	butyroxanIBA 01/01/1989 - "Clinical and laboratory studies have demonstrated the efficacy of adrenoblockers, pyrroxan and butyroxan, included in multiple-modality therapy for patients with manifest disorders of the autonomic nervous system" Get all the results and reference details, order at left...
6.	proroxanIBA 01/01/1989 - "Clinical and laboratory studies have demonstrated the efficacy of adrenoblockers, pyrroxan and butyroxan, included in multiple-modality therapy for patients with manifest disorders of the autonomic nervous system" Get all the results and reference details, order at left...
7.	Dopamine beta-HydroxylaseIBA 08/01/2002 - "Peripartum management of a patient with dopamine beta-hydroxylase deficiency, a rare congenital cause of dysautonomia." 06/01/1998 - "The sympathetic skin response in peripheral autonomic failure--evaluation in pure failure, pure cholinergic dysautonomia and dopamine-beta-hydroxylase deficiency." 07/15/2003 - "Recent findings of an association between human NE deficiency and variants at the dopamine beta-hydroxylase (DBH) gene [Kim et al., 2002] prompted us to investigate these markers in patients with autonomic disorders; 38 with orthostatic intolerance (OI), 26 with pure autonomic failure (PAF), and 39 with multiple system atrophy (MSA)" 07/15/2003 - "Variations in the dopamine beta-hydroxylase gene are not associated with the autonomic disorders, pure autonomic failure, or multiple system atrophy." 04/01/1995 - "1. The cardiovascular and catecholamine responses to supine leg exercise were measured in fifteen normal subjects (controls) and in three groups with sympathetic dysfunction: fifteen with central failure (Shy-Drager syndrome; SDS), fifteen with peripheral failure (pure autonomic failure; PAF) and two with isolated dopamine beta-hydroxylase deficiency (DBH deficiency)" Get all the results and reference details, order at left...
8.	Levodopa (L Dopa)FDA LinkGeneric 10/23/2007 - "Fourth, in the current era, most of the disability of advancing PD is from involvement of nondopaminergic systems, including levodopa-refractory motor symptoms, dementia, and dysautonomia" 10/01/1990 - "PET findings for the 10 MSA patients were compared with those for 13 age-matched controls, 8 subjects with L-dopa responsive Parkinson's disease (PD), and 7 subjects with pure autonomic failure (PAF)" 08/01/2006 - "While these and other motor signs typically improve with levodopa, the so-called axial signs, such as dysarthria, dysphagia, postural instability and freezing, and most nonmotor signs, such as depression, cognitive decline and dysautonomia, usually do not respond satisfactorily to levodopa" 09/05/2000 - "PATIENTS: 29 patients with Parkinson disease (9 with sympathetic neurocirculatory failure, 10 who had stopped receiving or had never been treated with L-dopa), 24 patients with multiple-system atrophy (17 with sympathetic neurocirculatory failure, 8 receiving L-dopa), 7 patients with pure autonomic failure, 33 controls with episodic or persistent orthostatic intolerance without sympathetic neurocirculatory failure, and 19 normal volunteers" 01/01/1998 - "The best, still not perfect, accuracy for this set of diagnostic criteria was obtained when six out of eight features (sporadic adult onset, dysautonomia, parkinsonism, pyramidal signs, cerebellar signs, no levodopa response, no cognitive dysfunction, or no downward gaze supranuclear palsy) were present (median sensitivity, 59%; range, 50-75%; positive predictive value: 67%, 53-83%)" Get all the results and reference details, order at left...
9.	Immunoglobulins (Immunoglobulin)IBA 02/08/2000 - "Acute idiopathic dysautonomia: electrophysiology and response to intravenous immunoglobulin." 05/01/2007 - "Immunoglobulin-responsive dysautonomia in Sjögren's syndrome." 11/01/1999 - "Acute dysautonomia secondary to autoimmune diseases: efficacy of intravenous immunoglobulin and correlation with a stimulation of plasma norepinephrine levels." 12/01/2003 - "Because of limited reports that intravenous immunoglobulin (IVIG) improves dysautonomia in primary SS, we investigated whether IVIG neutralizes the effect of anti-M3R antibodies on colon smooth muscle contractions, in an in vitro functional assay" Get all the results and reference details, order at left...
10.	BaclofenFDA LinkGeneric 10/01/2001 - "If a relapse of dysautonomia occurred at the end of the test period, an implantation of a continuous intrathecal infusion pump delivering Baclofen was performed" 10/01/2001 - "Within the framework of a prospective study, evaluating the efficacy of continuous intrathecal Baclofen therapy (CIBT) on hypertonia during the initial recovery phase of severe head injury, the authors report on the preliminary results of this treatment on paroxysmal dysautonomia about four patients" 10/01/2001 - "Dysautonomia syndrome in the acute recovery phase after traumatic brain injury: relief with intrathecal Baclofen therapy." 01/01/2008 - "These syndromes include Neuroleptic Malignant Syndrome, Serotonin Syndrome, Dysautonomia (or paroxysmal sympathetic storms) following acquired brain injury, Autonomic Dysreflexia, Parkinsonian-Hyperpyrexia Syndrome, Malignant Catatonia, intrathecal baclofen withdrawal, Malignant Hyperthermia, Stiff Man Syndrome and Irukandji Syndrome" 12/01/2002 - "Dysautonomia is difficult to manage and requires therapy with benzodiazepines, morphine, magnesium sulphate, adrenergic blockers and recently tried baclofen therapy" Get all the results and reference details, order at left...
148 Drugs and Important Bio-Agents and 213 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Denervation 01/01/2004 - "To determine the critical dependence of social and emotional behaviours on bodily responses mediated by the autonomic nervous system, we examined patients with pure autonomic failure (PAF), a peripheral denervation of autonomic neurons with onset in middle age" 04/01/2003 - "Pure autonomic failure (PAF) is characterized by an acquired, selective, peripheral denervation of the autonomic nervous system" 07/20/2001 - "Pure Autonomic Failure (PAF) is characterized by a global cardiovascular denervation" 12/01/2005 - "Thus, abnormal spontaneous activity or marked motor unit potential changes in sphincter muscles are helpful in distinguishing MSA from PD in the first five years after the onset of symptoms and signs, and from pure autonomic failure, as well as from cerebellar ataxias, if other causes for sphincter denervation have been ruled out" 11/01/2008 - "Cardiac denervation and dysautonomia in Parkinson's disease: A review of screening techniques." Get all the results and reference details, order at left...
2.	Sympathectomy (Sympathectomies) 06/01/2005 - "Data were compared with those from the interventricular septum of patients with cardiac sympathetic denervation associated with pure autonomic failure and from normal volunteers" 01/01/2005 - "The cardiovascular and cerebrovascular responses to head-up postural change are compromised in pure autonomic failure (PAF) patients because of sympathetic denervation" 09/01/2001 - "We therefore studied 14 subjects with documented sympathetic denervation due to pure autonomic failure, with continuous haemodynamic recordings obtained before and after ingestion of 500 ml of distilled water at room temperature" 09/01/1998 - "METHODS: SSRs were recorded from 6 non-Pa/P1 sites as well as palmar and plantar (Pa/P1) sites using magnetic neck stimulation in 33 normal subjects, 17 neurological patients with dysautonomia and one patient with lumbar sympathectomy" 09/01/1991 - "Biochemical evidence of sympathetic denervation of the heart in pure autonomic failure." Get all the results and reference details, order at left...
3.	Artificial Respiration (Mechanical Ventilation) 11/01/1958 - "New trial therapy of major autonomic nervous system disorders by intraventricular or subarachnoid procainization with endotracheal artificial respiration.]" 05/15/2004 - "Mortality from GBS most often is associated with dysautonomia and mechanical ventilation" 06/01/2001 - "RESULTS: Progression to mechanical ventilation was highly likely to occur in those patients with rapid disease progression, bulbar dysfunction, bilateral facial weakness, or dysautonomia" Get all the results and reference details, order at left...
4.	Mechanical Ventilators (Ventilator) 09/01/1997 - "Patients requiring ventilator support were more likely to have dysautonomia (P = 0.0009)" 09/01/1997 - "The objective of this study was to determine associations between early variables (requirement for ventilator support, anemia, indicators of abnormal peripheral nerve function (proprioception, vibratory, fine touch/pinprick, deep-tendon reflexes, cranial nerve involvement, dysautonomia, electrodiagnostic findings), plasmapheresis, age, and gender) and outcome variables (length of acute hospitalization, length of inpatient rehabilitation, Functional Independence Measure (FIM) Rasch converted scores, and acute and rehabilitation charges) in Guillain Barré Syndrome (GBS)" Get all the results and reference details, order at left...
5.	Plasmapheresis 09/01/1997 - "The objective of this study was to determine associations between early variables (requirement for ventilator support, anemia, indicators of abnormal peripheral nerve function (proprioception, vibratory, fine touch/pinprick, deep-tendon reflexes, cranial nerve involvement, dysautonomia, electrodiagnostic findings), plasmapheresis, age, and gender) and outcome variables (length of acute hospitalization, length of inpatient rehabilitation, Functional Independence Measure (FIM) Rasch converted scores, and acute and rehabilitation charges) in Guillain Barré Syndrome (GBS)" Get all the results and reference details, order at left...
26 Therapies and Procedures and 53 more articles analyzed in the Research Interface, order at left...