Atrazine

A selective triazine herbicide. Inhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans. Acutely poisoned sheep and cattle may show muscular spasms, fasciculations, stiff gait, increased respiratory rates, adrenal degeneration, and congestion of the lungs, liver, and kidneys. (From The Merck Index, 11th ed)

Also Known As:

Networked: 318 relevant articles (8 outcomes, 56 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Li, Jin-Long: 7 articles (06/2021 - 01/2016)
2.	Lin, Jia: 5 articles (06/2021 - 01/2016)
3.	Li, Xue-Nan: 5 articles (12/2018 - 01/2016)
4.	Rohr, Jason R: 5 articles (01/2018 - 10/2008)
5.	Hayes, Tyrone B: 5 articles (10/2011 - 04/2002)
6.	Kiran, Ravi: 5 articles (03/2011 - 07/2008)
7.	Sandhir, Rajat: 5 articles (03/2011 - 07/2008)
8.	Singh, Mohan: 5 articles (03/2011 - 07/2008)
9.	Abarikwu, Sunny O: 4 articles (01/2021 - 04/2010)
10.	Freeman, Jennifer L: 4 articles (01/2021 - 04/2013)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2013 - "A weight-of-evidence approach leads to the conclusion that there is no causal association between atrazine and cancer and that occasional positive results can be attributed to bias or chance. " 03/01/2013 - "The aim of this study was to evaluate the conflicting reports from the Environmental Protection Agency and the Scientific Advisory Panel (Panel) on the carcinogenicity of atrazine in order to determine whether the results from epidemiologic studies support a causal relationship between atrazine and any specific cancer. " 05/01/2007 - "This study highlights the importance of atrazine as a risk factor in endocrine disruption in wildlife and reproductive cancers in laboratory rodents and humans." 12/01/1994 - "However, a 24-month feeding study with atrazine (ATR) revealed a significant dose-related increase of mammary tumors in female Sprague-Dawley (SD) rats. " 12/01/2022 - "Atrazine is linked to endocrine disruption, neurotoxicity, and cancer, with delayed health effects observed after developmental exposure in line with the developmental origins of health and disease (DOHaD) hypothesis. "
2.	Starvation 01/01/2022 - "The atrazine degradation efficacy for Stenotrophomonas sp. strain SD2, Bacillus cereus strain BC3, and Paenarthrobacter ureafaciens strain AD3 was increased between 1.28 and 4.32 folds after the starvation process. " 05/01/1998 - "The bacteria exposed to atrazine in unsaturated sterile soil were still active after starvation period of 240 days: 15 mg newly added atrazine kg soil-1 was eliminated within 5 days." 02/01/2016 - "The two HR96 activators tested, atrazine and LA adversely reduce post-reproduction survival 70% during starvation and in turn show poor fecundity. " 09/10/2005 - "However, hyperactivity and faster active swimming speeds of exposed larvae indicated that naturally occurring sublethal levels of atrazine will result in an elevated rate of energy utilization (doubling the total metabolic rate), which is likely to increase the risk of death by starvation. " 01/01/2022 - "Effects of different parameters like mixing, starvation, UV exposure, and sodium citrate for enhancing the atrazine bioremediation process by identified bacteria were also studied. "
3.	Body Weight (Weight, Body) 09/01/2010 - "These studies have shown that short term exposure to atrazine during the freshwater phase of their lifecycle had no effects on subsequent survival, body weight, relative gonad size or various measures of iono-regulatory performance in juvenile Atlantic salmon upon transfer to seawater. " 09/01/2009 - "In the present study, we investigated the effects of oral dosing of atrazine (2-chloro-4-ethylamino-6-isopropylamino-s-triazine) to peripubertal male rats (50 and 200 mg/kg body weight daily from postnatal days 23-50) on ex vivo Leydig cell steroidogenesis. " 01/01/2001 - "At the termination of the study, the average body weight of rats receiving atrazine at 100 mg/kg per day was found to be reduced by approximately 9%. " 04/01/2014 - "Atrazine was administered orally at 50 or 200 mg/kg of body weight dose for 28 consecutive days. " 11/01/2011 - "Atrazine was administered by gavage daily to one group of rats at 50 mg/kg of body weight (bw) dose, to the second at 200 mg/kg bw while the third group was the control. "
4.	Chromosome Aberrations (Chromosome Abnormalities) 01/01/2022 - "pre and post showed a significant reduction in chromosomal aberrations induced by atrazine. " 01/01/2022 - "In the present study, its aqueous (leaves) extract was tested for genoprotective action against atrazine-induced chromosomal aberrations in the root tip cells of Allium cepa. " 01/01/2004 - "The present study was undertaken to add new data on the genotoxic potential of atrazine using the Allium cepa chromosome aberration test. " 01/01/2022 - "A critical analysis of results indicated that aqueous extract ameliorated the chromosomal aberrations caused by atrazine which may be be due to the increased expression level of CDKs genes." 01/01/2004 - "Atrazine produced a concentration-related increase in the number of total somatic chromosome aberrations, although this increase was statistically significant (p<0.05) only at the highest test concentration (5 microg/L). "
5.	Cardiotoxicity 08/01/2019 - "Cardiotoxicity in African clawed frog (Xenopus laevis) sub-chronically exposed to environmentally relevant atrazine concentrations: Implications for species survival." 04/01/2005 - "In acute toxicity studies, atrazine caused developmental toxicity in the rabbit [no observed effect level (NOEL) 5 mg kg(-1) day(-1)] and cardiotoxicity in a dog chronic study (NOEL 0.5 mg kg(-1) day(-1)); cancer (mammary glands) resulted from lifetime exposure. " 01/01/2016 - "The chemopreventive potential of lycopene against atrazine-induced cardiotoxicity: modulation of ionic homeostasis." 08/01/2014 - "From this current study, it can be concluded that administration of curcumin improved atrazine-induced cardiotoxicity through its modulatory effect on redox status, mitochondrial function, and caspase-3 expression."

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4.	Urea (Carbamide)
5.	Globulins
6.	Creatinine
7.	Albumins
8.	graphitic carbon nitride
9.	Herbicides
10.	Drinking Water

Related Therapies and Procedures

1.	Castration
2.	Prenatal Care (Care, Prenatal)
3.	Electrodes (Electrode)