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GTP Pyrophosphokinase (Stringent Factor)

An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent factor, is located in the relA gene in stringent strains of bacteria. The above synthesis is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding site of the ribosome by a codon-specific association. EC 2.7.6.5.
Also Known As:
Stringent Factor; ATP Guanosine Phosphate Pyrophosphotransferase; Factor, Stringent; Pyrophosphokinase, GTP; Pyrophosphotransferase, ATP-Guanosine Phosphate; ATP-Guanosine Phosphate Pyrophosphotransferase; ATP:GTP 3'-pyrophosphotransferase
Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Agirrezabala, Xabier: 1 article (09/2013)
2. Fernández, Israel S: 1 article (09/2013)
3. Kelley, Ann C: 1 article (09/2013)
4. Valle, Mikel: 1 article (09/2013)
5. Ramakrishnan, Venki: 1 article (09/2013)
6. Cartón, David Gil: 1 article (09/2013)
7. Chang, Sherman: 1 article (01/2007)
8. Ryding, Jamie: 1 article (01/2007)
9. Bibb, Mervyn: 1 article (01/2007)
10. Chen, Wenqiong Joan: 1 article (01/2007)

Related Diseases

1. Starvation
2. Polyploidy
3. Infection

Related Drugs and Biologics

1. GTP Pyrophosphokinase (Stringent Factor)
2. Transfer RNA (tRNA)
3. Guanosine Pentaphosphate
4. polyacrylamide