Astrocytoma (Pilocytic Astrocytoma)

Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
Also Known As:
Pilocytic Astrocytoma; Anaplastic Astrocytoma; Juvenile Pilocytic Astrocytoma; Subependymal Giant Cell Astrocytoma; Astrocytoma, Grade I; Astrocytoma, Grade II; Astrocytoma, Grade III; Astrocytoma, Protoplasmic; Astroglioma; Cerebral Astrocytoma; Childhood Cerebral Astrocytoma; Fibrillary Astrocytoma; Gemistocytic Astrocytoma; Intracranial Astrocytoma; Anaplastic Astrocytomas; Astrocytic Glioma; Astrocytic Gliomas; Astrocytoma, Anaplastic; Astrocytoma, Cerebral; Astrocytoma, Childhood Cerebral; Astrocytoma, Fibrillary; Astrocytoma, Gemistocytic; Astrocytoma, Intracranial; Astrocytoma, Juvenile Pilocytic; Astrocytoma, Pilocytic; Astrocytomas; Astrocytomas, Anaplastic; Astrocytomas, Cerebral; Astrocytomas, Childhood Cerebral; Astrocytomas, Fibrillary; Astrocytomas, Gemistocytic; Astrocytomas, Grade I; Astrocytomas, Grade II; Astrocytomas, Grade III; Astrocytomas, Intracranial; Astrocytomas, Juvenile Pilocytic; Astrocytomas, Pilocytic; Astrocytomas, Protoplasmic; Astrogliomas; Cerebral Astrocytoma, Childhood; Cerebral Astrocytomas; Cerebral Astrocytomas, Childhood; Childhood Cerebral Astrocytomas; Fibrillary Astrocytomas; Gemistocytic Astrocytomas; Gliomas, Astrocytic; Grade I Astrocytoma; Grade I Astrocytomas; Grade II Astrocytoma; Grade II Astrocytomas; Grade III Astrocytoma; Grade III Astrocytomas; Intracranial Astrocytomas; Juvenile Pilocytic Astrocytomas; Mixed Oligoastrocytoma; Mixed Oligoastrocytomas; Oligoastrocytomas, Mixed; Pilocytic Astrocytoma, Juvenile; Pilocytic Astrocytomas; Pilocytic Astrocytomas, Juvenile; Protoplasmic Astrocytoma; Protoplasmic Astrocytomas; Astrocytoma, Subependymal Giant Cell; Glioma, Astrocytic; Oligoastrocytoma, Mixed
Networked: 5136 relevant articles (165 outcomes, 785 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Glioblastoma (Glioblastoma Multiforme)
2. Neoplasms (Cancer)
3. Glioma (Gliomas)
4. Astrocytoma (Pilocytic Astrocytoma)
5. Oligodendroglioma


1. von Deimling, Andreas: 21 articles (12/2015 - 08/2002)
2. Reifenberger, Guido: 19 articles (08/2013 - 10/2002)
3. Ohgaki, Hiroko: 18 articles (10/2013 - 03/2002)
4. Jacobson, Kenneth A: 17 articles (05/2014 - 01/2002)
5. Weller, Michael: 16 articles (12/2013 - 10/2002)
6. Rutka, James T: 15 articles (11/2015 - 05/2002)
7. Eberhart, Charles G: 15 articles (02/2015 - 07/2004)
8. Gutmann, David H: 15 articles (10/2013 - 02/2002)
9. Guha, Abhijit: 15 articles (03/2013 - 03/2002)
10. Nakahata, Norimichi: 15 articles (03/2013 - 05/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Astrocytoma:
1. temozolomide (Temodar)FDA LinkGeneric
2. Etoposide (VP 16)FDA LinkGeneric
3. Sirolimus (Rapamycin)FDA Link
4. Carboplatin (JM8)FDA LinkGeneric
5. DNA (Deoxyribonucleic Acid)IBA
6. Carmustine (FIVB)FDA Link
7. Vincristine (Oncovin)FDA LinkGeneric
8. Phosphotransferases (Kinase)IBA
9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10. Cisplatin (Platino)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Adjuvant Chemotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Ketogenic Diet