HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Asphyxia (Suffocation)

A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.
Also Known As:
Suffocation; Suffocations; Asphyxias
Networked: 4644 relevant articles (162 outcomes, 525 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypothermia
2. Heart Arrest (Cardiac Arrest)
3. Hypoxia (Hypoxemia)
4. Seizures (Absence Seizure)
5. Brain Diseases (Brain Disorder)

Experts

1. Cheung, Po-Yin: 38 articles (01/2021 - 04/2005)
2. Bennet, Laura: 37 articles (06/2021 - 09/2003)
3. Groenendaal, Floris: 34 articles (07/2022 - 05/2004)
4. Gunn, Alistair J: 32 articles (08/2021 - 09/2003)
5. Schmölzer, Georg M: 23 articles (10/2022 - 01/2016)
6. Becker, Lance B: 23 articles (12/2021 - 05/2013)
7. Robertson, Nicola J: 22 articles (11/2021 - 09/2008)
8. Davidson, Joanne O: 21 articles (02/2021 - 01/2008)
9. Lee, Tze-Fun: 21 articles (01/2021 - 02/2011)
10. Thoresen, Marianne: 20 articles (06/2021 - 02/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Asphyxia:
1. Epinephrine (Adrenaline)FDA LinkGeneric
2. ErythropoietinFDA Link
3. Oxygen (Dioxygen)IBA
4. AcidsIBA
5. Phenobarbital (Luminal)FDA Link
6. MelatoninIBA
7. Lactic Acid (Lactate)FDA LinkGeneric
07/01/2008 - "The aim of the present study was (1) to evaluate the relationship between umbilical cord arterial blood lactate and pH, standard base excess (SBE), and actual base excess (ABE) at delivery and (2) to suggest a cut-off level of umbilical cord arterial blood lactate in predicting fetal asphyxia using ROC-curves, where an ABE value less than -12 was used as "gold standard" for significant intrapartum asphyxia. "
01/01/1984 - "The main findings were as follows: (a) myocardium: a release of HX early during asphyxia, the magnitude of which paralelled the amount of mechanical work performed by the heart; a significant lactate influx into the heart during normoxia and recovery period; (b) liver: hepatic HX release even during normoxia, increasing to substantial amounts in connection with increasing asphyxia; (c) hindleg: release of HX only during the recovery period; lactate efflux during all periods apart from severe asphyxia, when an influx was seen for both substances; (d) placenta: production of lactate during normoxia, and an efficient clearance of both lactate and HX from the fetal plasma in combination with their concentration increasing during asphyxia. "
12/01/2023 - "However, in this study, we observed that cases with a normal 5-min Apgar score, no suspected perinatal asphyxia, and a cord lactate value of ≥5 fell behind their peers when evaluated with the ACQ-3 developmental screening questionnaire."
12/01/2023 - "This study evaluated the effect of cord ABGA lactate level on the long-term neurodevelopment of newborns without any clinical signs of perinatal asphyxia. "
01/01/2021 - "The greatest sensibility and specificity in predicting intrapartum asphyxia were achieved in our study by using a cutoff value of 3.75 mmol/l for lactate and 7.24 for pH."
8. Dopamine (Intropin)FDA LinkGeneric
9. CreatineIBA
10. Aminophylline (Carine)FDA LinkGeneric

Therapies and Procedures

1. Resuscitation
2. Therapeutics
3. Induced Hypothermia
4. Induced Heart Arrest (Cardioplegia)
5. Cardiopulmonary Resuscitation (CPR)