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Asphyxia (Suffocation)

A pathological condition caused by lack of oxygen, manifested in impending or actual cessation of life.
Also Known As:
Suffocation; Suffocations; Asphyxias
Networked: 2944 relevant articles (89 outcomes, 299 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypothermia
2. Anoxia (Hypoxia)
3. Heart Arrest (Cardiac Arrest)
4. Brain Injuries (Brain Injury)
5. Hypercapnia

Experts

1. Bennet, Laura: 19 articles (12/2014 - 09/2003)
2. Cheung, Po-Yin: 16 articles (04/2013 - 04/2005)
3. Groenendaal, Floris: 14 articles (01/2015 - 05/2004)
4. Gunn, Alistair J: 13 articles (12/2014 - 09/2003)
5. Bigam, David L: 12 articles (04/2013 - 04/2005)
6. Herrera-Marschitz, M: 11 articles (05/2015 - 06/2000)
7. van Bel, Frank: 10 articles (01/2015 - 05/2004)
8. Gunn, A J: 10 articles (03/2010 - 01/2000)
9. Davidson, Joanne O: 9 articles (12/2014 - 01/2008)
10. Maeda, Hitoshi: 9 articles (11/2014 - 03/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Asphyxia:
1. Epinephrine (Adrenaline)FDA LinkGeneric
2. OxygenIBA
3. Dopamine (Intropin)FDA LinkGeneric
4. ErythropoietinFDA Link
5. Carbon MonoxideIBA
6. Lactic AcidFDA LinkGeneric
07/01/2008 - "The aim of the present study was (1) to evaluate the relationship between umbilical cord arterial blood lactate and pH, standard base excess (SBE), and actual base excess (ABE) at delivery and (2) to suggest a cut-off level of umbilical cord arterial blood lactate in predicting fetal asphyxia using ROC-curves, where an ABE value less than -12 was used as "gold standard" for significant intrapartum asphyxia. "
01/01/1984 - "The main findings were as follows: (a) myocardium: a release of HX early during asphyxia, the magnitude of which paralelled the amount of mechanical work performed by the heart; a significant lactate influx into the heart during normoxia and recovery period; (b) liver: hepatic HX release even during normoxia, increasing to substantial amounts in connection with increasing asphyxia; (c) hindleg: release of HX only during the recovery period; lactate efflux during all periods apart from severe asphyxia, when an influx was seen for both substances; (d) placenta: production of lactate during normoxia, and an efficient clearance of both lactate and HX from the fetal plasma in combination with their concentration increasing during asphyxia. "
06/01/2013 - "Intrapartum fetal asphyxia: study of umbilical cord blood lactate in relation to fetal heart rate patterns."
01/01/2015 - "Determination of lactate concentrations in serum of term newborns associated with risk factors for the perinatal asphyxia is a useful tool in diagnosing metabolic disorders and ischemic damage, particularly severe clinical forms (Tab. "
06/01/2013 - "There was no significant correlation between the Apgar score and blood lactate in all groups; however, the sensitivity and specificity of cord lactate to predict low score at 5 min were higher in comparison to cord pH. Umbilical cord blood lactate is a reliable marker for intrapartum fetal asphyxia compared to cord acid-base status with better prediction for newborns with low Apgar score."
7. Vasopressins (Vasopressin)IBA
8. Dihydrotachysterol (AT 10)IBA
9. MelatoninIBA
10. Glucose (Dextrose)FDA LinkGeneric

Therapies and Procedures

1. Resuscitation
2. Induced Heart Arrest (Cardioplegia)
3. Cardiopulmonary Resuscitation (CPR)
4. Lasers (Laser)
5. Perinatal Care