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Aryl Hydrocarbon Hydroxylases

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
Also Known As:
Microsomal Monooxygenases; Xenobiotic Monooxygenases; Hydroxylases, Aryl Hydrocarbon; Monooxygenases, Microsomal; Monooxygenases, Xenobiotic
Networked: 16 relevant articles (1 outcomes, 0 trials/studies)

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