Arsanilic Acid (Atoxyl)

An arsenical which has been used as a feed additive for enteric conditions in pigs and poultry. It causes blindness and is ototoxic and nephrotoxic in animals.

Also Known As:

Atoxyl; Sodium Arsanilate; 4-Aminobenzenearsonic Acid; Sodium Arsenilate; p-Aminophenylarsonic Acid; 4 Aminobenzenearsonic Acid; Acid, 4-Aminobenzenearsonic; Acid, Arsanilic; Acid, p-Aminophenylarsonic; Arsanilate, Sodium; Arsenilate, Sodium; p Aminophenylarsonic Acid

Networked: 40 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Arsenicals: 309
  - Arsanilic Acid: 40

Experts

1.	Ahamad, Rahmalan: 1 article (01/2015)
2.	Misni, Marpongahtun: 1 article (01/2015)
3.	MohdYusoff, Abdull Rahim: 1 article (01/2015)
4.	Sathishkumar, Palanivel: 1 article (01/2015)
5.	Duszenko, M: 1 article (01/2014)
6.	Gray, A: 1 article (01/2014)
7.	Huber, M: 1 article (01/2014)
8.	Meiwes, A: 1 article (01/2014)
9.	Mogk, S: 1 article (01/2014)
10.	Mudogo, C N: 1 article (01/2014)

Related Diseases

1.	Dysentery 01/01/2015 - "Para-arsanilic acid (p-ASA) has been widely used in the poultry industry to promote growth and prevent dysentery. " 07/01/1986 - "After an interim of no treatment for swine dysentery, sodium arsanilate was fed at a level of 220 parts per million for 21 days. " 07/01/1986 - "Beginning three weeks after the withdrawal of medication, all swine were fed sodium arsanilate at a concentration of 220 ppm of feed for three weeks in an attempt to excite the carrier of swine dysentery into developing a swine dysentery diarrhea. " 07/01/1986 - "From these results, it was theorized that sodium arsanilate excited the nondiarrhetic carrier into developing a swine dysentery diarrhea and that this phenomenon may have potential in identifying the carrier state." 07/01/1986 - "In the 14 pens containing swine fed sodium arsanilate, 14 swine were the first to develop a swine dysentery diarrhea since in four pens, two swine in each pen developed diarrhea within 24 hours of each other. "
2.	Lathyrism 06/01/1972 - "Protection against the neurolathyrism produced by arsanilic acid in the rat."
3.	Trypanosomiasis 01/19/1907 - "ATOXYL IN THE TREATMENT OF TRYPANOSOMIASIS." 09/14/1907 - "THE TREATMENT OF SLEEPING SICKNESS AND OTHER TRYPANOSOMIASES BY THE ATOXYL AND MERCURY METHOD." 01/01/1907 - "On the Treatment of Trypanosomiasis by Atoxyl (an Organic Arsenical Compound), followed by a Mercuric Salt (Mercuric Chloride) being a Bio-Chemical Study of the Reaction of a Parasitic Protozoon to Different Chemical Reagents at Different Stages of its Life History."
4.	Poisoning 09/01/1977 - "A common denominator in the ototoxic and the nephrotoxic actions of acute atoxyl poisoning might be a disturbance of the very active ion transport systems of the cells involved." 05/15/1974 - "[Semen quality and sexual behavior in boars following arsanilic acid poisoning]." 01/01/1973 - "Clinical, toxicological, and pathological aspects of arsanilic acid poisoning in swine." 11/30/1968 - "Experimental arsanilic acid poisoning in pigs." 02/15/1957 - "Arsanilic acid poisoning in swine."
5.	Delayed Hypersensitivity (Hypersensitivity, Type IV) 09/01/1965 - "Injections of various conjugates of arsanilic acid into newborn guinea pigs produced a specific tolerance in respect to subsequent development of hapten-specific delayed hypersensitivity. " 02/01/1966 - "Hapten-specific delayed hypersensitivity was produced by immunization of guinea pigs with arsanilic acid conjugated to N-acetyltyrosine or other small aromatic molecules. " 01/20/1967 - "Arsanilic acid conjugates of polymers of L-typrosine, glutamic acid, and alanine are immunogenic and can elicit hapten-specific, delayed-hypersensitivity reactions in sensitized guinea pigs. "

Related Drugs and Biologics

1.	Lincomycin (Lincocin)
2.	Ronidazole
3.	Carbadox
4.	Salts
5.	Mercuric Chloride (Sublimate)
6.	Indicators and Reagents (Reagents)
7.	Haptens
8.	Arsenic
9.	Roxarsone
10.	Arsanilic Acid (Atoxyl)

Related Therapies and Procedures

1.	Injections
2.	Investigational Therapies (Experimental Therapy)
3.	Intravenous Injections