|1.||Gao, Jiancao: 1 article (12/2014)|
|2.||Wang, Zaizhao: 1 article (12/2014)|
|3.||Zheng, Yao: 1 article (12/2014)|
|4.||Wu, Feili: 1 article (12/2014)|
|5.||Chen, Shu: 1 article (12/2014)|
|6.||Rahman, Saydur: 1 article (01/2011)|
|7.||Thomas, Peter: 1 article (01/2011)|
|8.||Khan, Izhar A: 1 article (01/2011)|
|9.||Kimbrough, Renate: 1 article (01/2009)|
|10.||Golden, Robert: 1 article (01/2009)|
01/01/2009 - "Aroclors) did not pose a cancer risk to humans ( Golden et al. (2003) . "
01/01/1998 - "A significantly decreased trend in the incidence of mammary gland neoplasms compared to control was also noted for females receiving Aroclors 1242, 1254, and 1260."
11/01/1995 - "Dietary Aroclor significantly promoted liver tumors in C57BL/6 mice (59 versus 14%) but not in B6D2F1 mice (24 versus 21%). "
11/01/1995 - "Aroclor caused an 8-fold induction of hepatic Cyp 2b, which was its maximum at the 12-week time point but did not promote tumors. "
11/01/1994 - "Analytical chemistry was used to quantitate the amount of Aroclor per tumor cell population and compared directly to flow cytometric results. "
|2.||Hepatocellular Carcinoma (Hepatoma)
02/01/1996 - "In order to determine the role of biotransformation in the tumor-promoting activity of PB, its effect on GJIC was also examined in the presence of an Aroclor 1254-induced rat liver homogenate (S9 mix) and in the hepatoma cell line HepG2. "
07/01/1982 - "Four Aroclor reference materials, cleaned-up extracts of 2 yusho rice oil samples, and cleaned-up extracts of 3 fish samples containing polychlorinated biphenyl (PCB) residues were tested for their ability to induce aryl hydrocarbon hydroxylase (AHH) activity in a rat hepatoma cell line. "
11/01/1977 - "At the end of the year, 26 of 37 (70.3%) trout fed 6 ppb AFB1 had hepatocellular carcinomas, compared to 14 of 46 (30.4%) trout fed 6 ppb AFB1 plus 100 ppm Aroclor 1254, a highly significant reduction in tumor incidence in the trout on the Aroclor 1254-containing diet. "
07/01/2008 - "NTA was assayed in the Ames test using TA1537, TA98, TA100, and TA102 tester strains, and in the in vitro micronucleus assay on L5178Y mouse lymphoma cells and on CTLL2 and CTLL2/Bcl2 cells coupled to the apoptosis measurement, both with and without metabolic activation by aroclor 1254-induced liver or kidney rat S9-mix. "
01/01/2000 - "Both DMP and DBP were found to produce significant increases in the mutant frequency in the mouse lymphoma assay in the presence but not in the absence of an Aroclor-induced rat liver activation system (S-9). "
11/01/1987 - "The present studies show that MP is a moderately active mutagen in the L5178Y/TK +/-----TK-/- mouse lymphoma assay (MLA) in the presence of aroclor-induced rat-liver S9, and that it induces predominantly small-colony thymidine kinase-deficient (TK-/-) mutants of demonstrated chromosomal origin. "
03/01/1988 - "Procarbazine (Natulan) is a potent inducer of gene mutations at the heterozygous tk +/- locus in L5178Y mouse lymphoma cells in the presence of Aroclor-induced rat liver S9 metabolic activation (approximately 10(-3) mutant frequency at 10 micrograms/ml) while exerting a far weaker effect in the absence of S9. "
01/01/1984 - "Lesions seen exclusively in an Aroclor 1254-treated monkey were widespread mucinous metaplasia and hyperplasia of the fundic mucosa. "
12/01/1981 - "Aroclor 1254-induced intestinal metaplasia and adenocarcinoma in the glandular stomach of F344 rats."
07/01/2008 - "Dietary vitamin A concentration (0 or 5 international units/g in the diet) and OC exposure (no OC compound or the mixture of 2 mg/kg chlordane, 0.25 mg/kg aroclor, and 1 mg/kg lindane) did not affect histologic score based on degree of squamous metaplasia of the tympanic epithelium or levels of plasma or liver vitamin A among the study groups. "
|5.||Body Weight (Weight, Body)
08/01/2001 - "American kestrels ingested 7 mg/kg/body weight/bird/day of a 1:1:1 mixture of Aroclors 1248, 1254, and 1260 through their diet of day-old cockerels. "
03/01/1994 - "Liver/body weight ratios also increased, with the maximum ratios observed at the highest Aroclor dose, and were associated with histopathologic hepatocyte lesions. "
01/01/1991 - "At both time points Aroclor 1254-treated rats had significantly lower body weights and higher liver weights while kidney and lung weights were unaffected. "
05/01/1993 - "A significant inhibition in body weight gain was observed only in rats treated with high doses of Aroclors 1232 and 1248 and thymic atrophy was not observed for any of the Aroclors. "
02/01/2006 - "Captive kestrels were fed a mixture of PCBs (Aroclors 1248:1254:1260) at an approximate daily dose of 7 mg/kg body weight, 1 month prior to pairing and throughout incubation. "
|1.||Chlorodiphenyl (54% Chlorine)
|2.||Vitamin A (Retinol)
|6.||Polychlorinated Biphenyls (PCBs)
|8.||Cytochrome P-450 CYP1A1 (CYP1A1)
|10.||Corn Oil (Oil, Corn)