|1.||Häberle, Johannes: 6 articles (11/2015 - 10/2002)|
|2.||Nuoffer, Jean-Marc: 4 articles (09/2015 - 01/2012)|
|3.||Eggimann, Sandra: 3 articles (09/2015 - 01/2012)|
|4.||Hu, Liyan: 3 articles (09/2015 - 01/2012)|
|5.||Rüfenacht, Véronique: 3 articles (09/2015 - 11/2013)|
|6.||Pandey, Amit V: 3 articles (09/2015 - 11/2013)|
|7.||Lai, Ming-Derg: 2 articles (12/2015 - 11/2013)|
|8.||Cho, Chien-Yu: 2 articles (12/2015 - 11/2013)|
|9.||Hsu, Hui-Ping: 2 articles (12/2015 - 11/2013)|
|10.||Chen, Wei-Ching: 2 articles (12/2015 - 11/2013)|
04/01/1999 - "We also used MS/MS analysis of urine or blood either for confirmation of initial positive results or for follow-up of treatment, such as in glutaric acidemia, citrullinemia, argininosuccinase deficiency, and biopterin-dependent phenylketonuria."
03/01/2010 - "Argininosuccinate synthetase deficiency was the most frequent disease (17/37, 46%), followed by ornithine transcarbamylase (10/37, 27%), arginase (7/37, 19%), and argininosuccinate lyase (3/37, 8%) deficiencies. "
04/01/1976 - "Increased urinary levels of N-carbamoyl-beta-alanine, and also, on occasions, of N-carbamoylaspartate, were observed in patients with ornithine carbamoyl-transferase (EC 22.214.171.124) deficiency, argininosuccinate synthetase (EC 126.96.36.199) deficiency and argininosuccinate lyase (EC 188.8.131.52)deficiency, but not in a patient with carbamoylphosphate synthase deficiency. "
10/01/2013 - "This encompasses 5 major disorders, corresponding with deficiency of each step in the urea cycle, namely ornithine transcarbamoylase (OTC) deficiency, argininosuccinate lyase (ASL) deficiency, carbamoyl phosphate synthetase (CPS) deficiency, citrullinemia and argininemia. "
12/05/2002 - "In this review, the differential diagnosis for hyperammonemia are described; deficiencies of ornithine carbamoyl transferase, argininosuccinate synthase (citrullinemia), argininosuccinate lyase and arginase, lysinuric protein intolerance, hyperammonemia-hyperornithinemia-homocitrullinemia syndrome, and citrullinemia type II. The diagnosis of IEM of purine and pyrimidine such as deficiencies of hypoxanthine-guanine phosphoribosyl transferase, adenine phosphoribosyl transferase, dihydropyrimidine dehydrogenase, dihydropyrimidinase and beta-ureidopropionase are described. "
|3.||Liver Diseases (Liver Disease)
01/01/2008 - "Study of serum argininosuccinate lyase determination for diagnosis of liver diseases."
07/01/2007 - "To investigate the value of the determination of the levels of serum argininosuccinate lyase (ASL) in diagnosing various liver diseases. "
07/01/2007 - "[Determination of serum argininosuccinate lyase in diagnosing liver diseases]."
12/01/1998 - "Argininosuccinate lyase: a new autoantigen in liver disease."
08/01/1987 - "A rapid enzymatic method was developed for the assay of serum argininosuccinate lyase (ASAL: EC 184.108.40.206) which is a useful marker enzyme for diagnosis of parenchymal liver diseases. "
12/01/2015 - "In our previous study, we observed that blocking argininosuccinate lyase (ASL) attenuates tumor progression in liver cancer. "
01/01/2013 - "Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells."
11/01/2013 - "Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide."
05/08/2009 - "Expression profiling of argininosuccinate synthetase (ASS), argininosuccinate lyase (ASL) and OTC in 40 HCC tumor biopsy specimens predicted that 16 of the patients would be rhArg-sensitive, compared with 5 who would be sensitive to arginine deiminase (ADI), another arginine-depleting enzyme with anti-tumor activity. "
11/01/2000 - "We have identified the enzyme argininosuccinate lyase (ASL) as being downregulated by hypoxia. "
11/01/2000 - "Identification of argininosuccinate lyase as a hypoxia-responsive gene in rat hepatocytes."
11/01/1995 - "The conversion of argininosuccinate to arginine by argininosuccinate lyase was inhibited by exposure to hypoxia for 24 h but not for 4-12 h. "
09/01/2000 - "In this study, we evaluated the influence of hypobaric hypoxia on the expression of NOS isoforms, argininosuccinate synthetase (AS), argininosuccinate lyase (AL), and manganese superoxide dismutase (Mn SOD) in the ventilatory muscles. "
01/01/2010 - "The increased activities of argininosuccinate synthetase and argininosuccinate lyase suggest the increased and effective recycling of citrulline to arginine in anoxia, making nitric oxide production more effective and contributing to its toxic effects. "
|2.||Argininosuccinate Synthase (Argininosuccinate Synthetase)
|4.||Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)
|8.||Protein Isoforms (Isoforms)
|1.||Protein-Restricted Diet (Diet, Protein Restricted)