Arginine Kinase

An enzyme that catalyzes the phosphorylation of the guanidine nitrogen of arginine in the presence of ATP and a divalent cation with formation of phosphorylarginine and ADP. EC 2.7.3.3.

Also Known As:

Networked: 50 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Pereira, Claudio A: 3 articles (06/2016 - 01/2002)
2.	Cai, Qiu-Feng: 2 articles (01/2012 - 05/2011)
3.	Cao, Min-Jie: 2 articles (01/2012 - 05/2011)
4.	Liu, Guang-Ming: 2 articles (01/2012 - 05/2011)
5.	Su, Wen-Jin: 2 articles (01/2012 - 05/2011)
6.	Yu, Hui-Lin: 2 articles (01/2012 - 05/2011)
7.	Alonso, G D: 2 articles (06/2001 - 01/2000)
8.	Flawiá, M M: 2 articles (06/2001 - 01/2000)
9.	Paveto, M C: 2 articles (06/2001 - 01/2000)
10.	Pereira, C A: 2 articles (06/2001 - 01/2000)

Related Diseases

1.	Hypersensitivity (Allergy) 05/01/2017 - "Although improved allergy diagnosis is required, molecular characterization of silkworm allergens has not been performed to date, except for Bomb m 1, an arginine kinase. " 07/01/2015 - "Subjects with dust mite and/or cockroach allergy not sensitized to shrimp recognized arginine kinase and hemocyanin. " 01/30/2012 - "Induction of mud crab (Scylla paramamosain) tropomyosin and arginine kinase specific hypersensitivity in BALB/c mice." 06/01/2006 - "Periplaneta americana arginine kinase as a major cockroach allergen among Thai patients with major cockroach allergies." 05/01/2011 - "Although crustaceans have been reported to be one of the most common causes of IgE-mediated allergic reactions, there are no reports about the characterization and identification of arginine kinase (AK) from the mud crab (Scylla serrata) as allergen. "
2.	Starvation 08/30/2002 - "Such arginine kinase-expressing yeast showed improved resistance under two stress challenges that drain cellular energy, which were transient pH reduction and starvation. " 06/01/2001 - "Arginine kinase could be proposed as a modulator of energetic reserves under starvation stress condition." 08/30/2002 - "Although transient starvation led to 50% reduced intracellular ATP concentrations in wild-type yeast, arginine kinase overexpression stabilized the ATP pool at the pre-stress level. " 01/01/2014 - "In different unicellular and multicellular organisms including trypanosomatids, it was demonstrated that arginine kinase is an important component in resistance mechanisms to different stress factors, such as reactive oxygen species, trypanocidal drugs, pH and starvation. " 12/05/2003 - "The starvation-induced degradation of the beta-galactosidase reporter protein is quantitatively similar to that of two endogenous muscle proteins, arginine kinase and adenylate kinase. "
3.	Trypanosomiasis 11/01/2013 - "Arginine kinase is not only absent from mammalian hosts but is critical to the survival of trypanosomes under stressful conditions and consequently its inhibition may lead to an effective treatment for trypanosomiasis. " 01/01/2014 - "Arginine kinase of trypanosome has been validated as target for drug development against trypanosomiasis. " 01/01/2014 - "Arginine kinase: a potential pharmacological target in trypanosomiasis."
4.	Infections 01/01/2017 - "IMPORTANCE The interaction of Cdc42 with arginine kinase plays a crucial role in the host defense against WSSV infection. " 01/01/2015 - "The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies." 04/10/2014 - "Arginine kinase of Litopenaeus vannamei involved in white spot syndrome virus infection." 03/01/2011 - "These findings suggest that arginine kinase is involved in the antiviral process of Bombyx mori larvae against NPV infection." 09/01/1993 - "Moreover, kinetic experiments, employing saturation transfer, demonstrated the pseudo-first-order rate constant for the arginine kinase-catalysed exchange reaction in the forward direction, that is, PA-->ATP was decreased by infection. "
5.	Hypoxia (Hypoxemia) 10/01/2011 - "Regulation of tail muscle arginine kinase by reversible phosphorylation in an anoxia-tolerant crayfish." 01/01/1996 - "Conversely, arginine kinase, from the myocardium of Limulus polyphemus, a species that tolerates anoxia for days was 2.9-fold less susceptible to oxidative inactivation. " 01/01/1991 - "The effects of PCP were similar to those of hypoxia, fatigue, hypersalinity, and arginine kinase inhibitors, and so sublethal PCP concentrations may also inhibit electron transport and arginine kinase as well as uncouple mitochondrial oxidative phosphorylation in intact molluscs. " 01/01/2007 - "This arginine kinase up-regulation under hypoxia may indicate a provision for oxygen re-supply after anaerobiosis. " 01/01/2007 - "Several partial sequences from three protein spots up-regulated under hypoxia were all assigned to arginine kinase, suggesting the existence of several isoforms of arginine kinase in the muscle of M. "

Related Drugs and Biologics

1.	Allergens
2.	Tropomyosin
3.	Proteins (Proteins, Gene)
4.	Immunoglobulin E (IgE)
5.	Myosin Light Chains (Myosin Essential Light Chain)
6.	Hemocyanins
7.	Immunoglobulin G (IgG)
8.	14-3-3 Proteins (14-3-3 Protein)
9.	Sodium Azide
10.	Pentachlorophenol (Sodium Pentachlorophenate)

Related Therapies and Procedures

1.	Immunotherapy
2.	Drug Therapy (Chemotherapy)