Arbovirus Infections

08/14/2023 - "Detection of Anti-Rift Valley Fever Virus Antibodies in Serum Samples of Patients with Suspected Arbovirus Infection."
01/01/2023 - "Diagnosis of arbovirus infection or exposure by antibody testing is becoming increasingly difficult due to global expansion of arboviruses, which induce antibodies that may (cross-)react in serological assays. "
03/24/2021 - "Diagnostic Performance of a Magnetic Field-Enhanced Agglutination Readout in Detecting Either Viral Genomes or Host Antibodies in Arbovirus Infection."
01/01/2020 - "The small volumes of blood present in mosquito abdomens can be used to identify RRV antibodies and therefore host exposure to arbovirus infection. "
01/01/1990 - "Anti-mosquito antibodies reduce the susceptibility of Aedes aegypti to arbovirus infection."

01/01/2019 - "We identified 13 patients with concurrent or consecutive infections (IgM positive for more than one arbovirus), including 11 individuals that were positive for CHIKV and other previously confirmed arbovirus infection. "
05/01/1999 - "We report the clinical forms of Chikungunya virus infections, the interest in detecting IgM for recent arbovirus infections and the duration of these IgM. "
01/28/2016 - "Malaria parasite infections were investigated using thick blood smear (TBS) and rapid diagnostics tests (RDT) while arbovirus infections were tested by IgM antibody detection (ELISA) and RT-PCR assays. "
01/01/2020 - "Considering the epidemic outbreak of arbovirus infections in countries neighbouring Iran, we performed this study to estimate the possibility of chikungunya and dengue fever among measles and rubella IgM negative patients presenting with rash and fever from December 2016 to November 2017 in the National Measles Laboratory at Tehran University of Medical Sciences. "
01/01/2020 - "They were classified as high probability: typical clinical picture of arbovirus infection (i.e., fever, chills, headaches, muscle, and joint pains) and IgM seroconversion; medium probability: typical clinical picture + single positive IgM on a unique serum sample without control; and low probability: atypical clinical picture of infection and single positive IgM. "

09/01/2021 - "The present review decodes scientific reports on medicinal plants against chikungunya virus (CHIKV) infection and demystifies the potential phytoconstituents which reveals that the screening of flavonoids containing plants and phytochemicals showing efficacy against other arbovirus infections, may prove as a potential lead for drug development against CHIKV. "

09/01/2021 - "The present review decodes scientific reports on medicinal plants against chikungunya virus (CHIKV) infection and demystifies the potential phytoconstituents which reveals that the screening of flavonoids containing plants and phytochemicals showing efficacy against other arbovirus infections, may prove as a potential lead for drug development against CHIKV. "

08/04/2023 - "In addition, antiviral compounds reduced arbovirus infection in the cultured gut tissue. "
06/17/2020 - "Antiviral Natural Products for Arbovirus Infections."
01/01/2020 - "The mosquito antiviral response has mainly been studied in the context of arthropod-borne virus (arbovirus) infection in female mosquitoes. "
01/01/2020 - "Over the past few years, several investigations have been carried out to identify antiviral agents to treat these arbovirus infections. "
01/01/2019 - "Here, we review recent developments in our understanding of the immune response, with an emphasis on the early antiviral immune response mediated by natural killer cells and emphasize their Janus-faced effects in the control of arbovirus infection and pathogenesis. "

01/05/2021 - "Nanoparticles as Vaccines to Prevent Arbovirus Infection: A Long Road Ahead."
01/01/2019 - "Although vaccine development for prevention of mosquito-borne arbovirus infections has been a focus, mitigation strategies continue to rely on vector control. "
01/01/2013 - "Human disease incidence attributed to arbovirus infection is increasing throughout the world, with effective control interventions limited by issues of sustainability, insecticide resistance and the lack of effective vaccines. "
07/01/2009 - "The plaque reduction neutralization test (PRNT) is a specific serological test used to identify and confirm arbovirus infection in diagnostic laboratories and monitor immunological protection in vaccine recipients. "
12/01/2023 - "The permissiveness of CxTr cells to arbovirus infection was investigated with vaccine and wildtype arboviruses from four viral families: Flaviviridae (Japanese encephalitis virus), Phenuiviridae (Rift Valley fever phlebovirus), Rhabdoviridae (vesicular stomatitis virus), and Togaviridae (Mayaro virus). "

01/01/1984 - "Very few studies concern interferon and arbovirus infections in humans. "
01/01/2019 - "Adult mice with gene knockouts of the interferon α/β (IFN-α/β) receptor (IFNAR(-/-)) have been described as a model of arbovirus infections. "
05/01/1975 - "[Interferon production in vitro (by leukocytes) in response to arbovirus infections]."
07/01/1972 - "[Combined use of interferon and various styrylquinolines in cell cultures and experimental arbovirus infections]."
05/01/1971 - "[The mechanism of interferon induction and its effect in tissue culture arbovirus infections]."

03/05/2009 - "The goal of this study was to use a recombinant Sindbis virus (SINV; family Togaviridae; genus Alphavirus) that expresses B2 protein of Flock House virus (FHV; family Nodaviridae; genus Alphanodavirus), a protein that inhibits RNAi, to determine the effects of linking arbovirus infection with RNAi inhibition. "
01/01/2017 - "In the vector mosquito Aedes aegypti, the presence of eight PIWI proteins and the accumulation of viral piRNAs upon arbovirus infection suggest additional functions of the piRNA pathway beyond genome defense. "
07/01/2013 - "In conclusion, arbovirus infection can trigger the piRNA pathway in mosquito cells, and knockdown of piRNA proteins enhances virus production."
01/01/1970 - "Influence of an arbovirus infection (Sindbis virus) on the protein and ribonucleic acid synthesis of cultivated chick embryo cells."

01/01/2019 - "Taken together, these studies suggest that atovaquone could be a broad-spectrum antiviral drug and a potential attractive candidate for the prophylaxis or treatment of arbovirus infection in vulnerable populations, such as pregnant women and children.IMPORTANCE The ability to protect vulnerable populations such as pregnant women and children from Zika virus and other arbovirus infections is essential to preventing the devastating complications induced by these viruses. "

02/01/2000 - "This study indicates that congenital arbovirus infections may predispose calves to ocular diseases, especially retinal atrophy."

03/01/2018 - "The data presented show a need to strengthen preparedness for (re-)emerging arbovirus infections and a need for research into neglected arboviruses, risks of non-vector transmission and effective therapeutics and vaccinations."
01/01/2013 - "[Immunotropic therapy of arbovirus infections in children]."
12/01/1989 - "Postinfection therapy of arbovirus infections in mice."
01/01/2020 - "Instead, we have defined and targeted a key aspect of the host innate immune response to virus at the arthropod bite that is common to all arbovirus infections, potentially circumventing the need for virus-specific therapies. "
11/01/2016 - "Problematic issues on creation and practical introduction of specific immune biologic prepa- rations for therapy and prophylaxis of natural-foci arbovirus infections - West Nile fever (WNF) and Crimean hemorrhagic fever (CHF), that are not available until now, are examined. "

03/01/1993 - "These findings may help explain the increased thresholds of infection associated with artificial feeding techniques and indicate that artificial blood meals may alter the sites of initial arbovirus infection within the alimentary tract of mosquito vectors."

06/01/1975 - "The arbovirus antibody titers were determined in four out of six HB Ag positive cases that did not give a history of parenteral injections and in everyone of them the titers were suggestive of a recent arbovirus infection."