Arachnoiditis

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260 relevant articles (6 outcomes, 23 trials/studies) found for this Disease

Description: Acute or chronic inflammation of the arachnoid membrane of the meninges most often involving the spinal cord or base of the brain. This term generally refers to a persistent inflammatory process characterized by thickening of the ARACHNOID membrane and dural adhesions. Associated conditions include prior surgery, infections, trauma, SUBARACHNOID HEMORRHAGE, and chemical irritation. Clinical features vary with the site of inflammation, but include cranial neuropathies, radiculopathies, and myelopathies. (From Joynt, Clinical Neurology, 1997, Ch48, p25)

Also Known As:

Arachnoid Membrane Inflammation; Inflammation, Arachnoid Membrane; Arachnoid Membrane Inflammations; Arachnoiditides; Inflammations, Arachnoid Membrane

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3405

Central Nervous System Diseases: 929

Central Nervous System Infections: 237

Meningitis: 5699

Arachnoiditis: 260

Related Diseases

1.	Syndrome
2.	Pain (Aches)
3.	Wounds and Injuries (Trauma)
4.	Infection
5.	Dystonia (Limb Dystonia)
91 Diseases and 106 more articles analyzed in the Research Interface, order at left...

Experts

1.	Bhadelia, Rafeeque A: 1 article (03/2008)
2.	Hwang, Steven W: 1 article (03/2008)
3.	Wu, Julian: 1 article (03/2008)
4.	Navas Vinagre, I: 1 article (01/2008)
5.	Longoni Merino, M: 1 article (01/2008)
6.	Garriga Biosca, R: 1 article (01/2008)
7.	Fernández Cañabate, E: 1 article (01/2008)
8.	Joshi, Shabin Man: 1 article (10/2006)
9.	Sabin, Ian: 1 article (10/2006)
10.	Gnanalingham, Kanna K: 1 article (10/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Arachnoiditis:

1.	Iophendylate (Iofendylate)FDA Link 04/01/1976 - "Chronic arachnoiditis after a pantopaque study of the posterior fossa." 08/01/1966 - "Experimental studies of pantopaque arachnoiditis" 08/01/1966 - "Experimental studies of pantopaque arachnoiditis" 08/01/1966 - "Experimental studies of pantopaque arachnoiditis" 04/01/1966 - "Pantopaque arachnoiditis--an experimental and clinical study." Get all the results and reference details, order at left...
2.	Metrizamide FDA Link 01/01/1977 - "The advantages of myelography with metrizamide (Amipaque) are so great in terms of improved diagnostic accuracy, no withdrawal of contrast medium and reduced incidence of arachnoiditis that it is firmly believed that this technique will soon replace oily myelography as standard practice, at least for the lumbar and thoracic regions." 02/17/1978 - "Remyelography after an interval of longer than 2 months showed that in one case there was progression of an arachnoiditis which had already been present during the first Amipaque study" 01/01/1988 - "Measurement of trigeminal cistern volume at the first and second procedure with metrizamide showed a significant decrease in the cistern volume from 0.38 ml to 0.29 ml. Clumping of nerve roots indicative of arachnoiditis was observed in 4 cases" 01/01/1987 - "Metrizamide myelogram on admission revealed the findings of adhesive arachnoiditis" 05/01/1983 - "On immediate and/or delayed CT scans, metrizamide accumulation within the central part of the cord was identified, both at and above the level of the arachnoiditis" Get all the results and reference details, order at left...
3.	Hyaluronoglucosaminidase (Hyaluronidase)FDA Link 09/01/1984 - "Because of this therapeutic efficacy and lack of serious toxic effects, intrathecally administered hyaluronidase appears to be of value in the management of spinal arachnoiditis." 03/01/1991 - "Thus this study provides convincing evidence of the therapeutic role of hyaluronidase in the management of tuberculous spinal arachnoiditis and replicates our earlier observation of the safety of hyaluronidase given intrathecally." 01/01/2008 - "Administration of intrathecal hyaluronidase in a patient diagnosed with adhesive arachnoiditis]" 03/01/1991 - "Hyaluronidase as an adjuvant in the management of tuberculous spinal arachnoiditis." 09/01/1986 - "Intrathecal hyaluronidase therapy in tuberculous spinal arachnoiditis." Get all the results and reference details, order at left...
4.	Morphine (MS Contin)FDA LinkGeneric 10/01/1996 - "To ascertain the efficacy of the morphine pump, we reviewed the 2-year results of continuous INA in 18 patients with failed back syndrome or arachnoiditis and intractable, debilitating pain that was unrelieved by conventional means" 06/01/1994 - "An implantable, externally programmable infusion pump was used for intraspinal delivery of morphine sulfate to 15 patients with intractable pain from reflex sympathetic dystrophy, arachnoiditis after spinal surgery, or an unknown cause" 11/01/1989 - "Intraventricular or epidural injection of morphine through implantable infusion devices was used for severe pain in 50 patients with advanced cancer, arachnoiditis, or spinal injury" 01/01/1982 - "Elevated cerebrospinal fluid substance P in arachnoiditis is reduced by systemic administration of morphine." Get all the results and reference details, order at left...
5.	Methylprednisolone FDA LinkGeneric 03/01/1978 - "Prophylactic intrathecal methylprednisolone was not effective in preventing arachnoiditis" 10/01/1988 - "No apparent protection against Pantopaque arachnoiditis was provided by either intrathecal or intramuscular methylprednisolone" 07/15/1997 - "In Australia, reports of possible adverse effects of Depo-Medrol (methylprednisolone), including the complication of arachnoiditis, have been followed by statements from the manufacturers of commonly used steroid preparations recommending they should not be administered epidurally" Get all the results and reference details, order at left...
6.	Detergents (Detergent)IBA 07/01/1955 - "Adhesive arachnoiditis and vascular blockage caused by detergents and other chemical irritants: an experimental study." 05/01/1955 - "Adhesive arachnoiditis and vascular blockage caused by detergents and other chemical irritants; an experimental study." 01/01/1954 - "Role of intrathecal detergents in pathogenesis of adhesive arachnoiditis." 07/01/1988 - "4) When that glycol, which is both alcohol and detergent, is injected intraspinally, sterile meningitis, arachnoiditis, or pachymeningitis will occur" 01/01/2003 - "Regarding regional anesthesia in the neuroaxis, arachnoiditis has resulted from epidural abscesses, traumatic punctures (blood), local anesthetics, detergents, antiseptics or other substances unintentionally injected into the spinal canal" Get all the results and reference details, order at left...
7.	Iohexol (Omnipaque)FDA Link 07/01/1982 - "Experimental study of arachnoiditis from iohexol, an investigational nonionic aqueous contrast medium." 07/01/1982 - "No significant evidence of arachnoiditis was seen in any of the eight animals examined with iohexol." 06/01/1993 - "The use of adsorbable, nonirritative contrast materials such as Iohexol Parenteral will result in a marked reduction in the frequency of occurrence of arachnoiditis." 10/01/1988 - "We found no histologic evidence of arachnoiditis in animals examined with iopamidol and iohexol." 01/01/1985 - "Under adverse conditions, high doses and high concentrations of iohexol produced little arachnoiditis, while metrizamide produced mild to moderate arachnoiditis" Get all the results and reference details, order at left...
8.	Contrast MediaIBA 05/01/2001 - "The reported incidence of clinically significant arachnoiditis following oil-based contrast media myelography is approximately 1%" 02/01/1995 - "It was concluded that arachnoiditis does occur after extradural lumbar disc surgery independently of the use of some myelographic contrast media, and that it may be diffuse or confined only to the operated level" 02/01/1995 - "Myelography using oil-based or ionic water-soluble contrast media was a major contributing factor, and it was not possible to distinguish the prevalence of arachnoiditis probably due to surgery alone" 02/01/1994 - "Few descriptive reports are available of the myelographic appearance, with water-soluble contrast media, in tuberculous radioculomyelitis (arachnoiditis)" 09/01/1992 - "Chronic lumbar arachnoiditis has numerous causes, including the introduction of contrast media into the lumbar subarachnoid space" Get all the results and reference details, order at left...
9.	KaolinIBA 04/01/2008 - "Kaolin (5 microl of 500 mg/ml solution) was then injected into the subarachnoid space rostral to the site of the injury to induce inflammatory arachnoiditis in 22 rats" 10/01/1987 - "Histologic examination revealed moderate to severe arachnoiditis in the kaolin-treated animals and no evidence of arachnoid abnormalities in the controls" 01/01/1975 - "These results suggest that in addition to kaolin-induced arachnoiditis, increased intraluminal pressure is necessary to enlarge the central canal." 01/01/1975 - "Kaolin-induced arachnoiditis completely obstructed communication between the ventricles and the cranial subarachnoid space" 12/01/1992 - "In order to produce syringomyelia, localized arachnoiditis was created in adult New Zealand albino rabbits and Wistar rats by the injection of kaolin into the thoracic spinal subarachnoid space and incision of the dura mater of the thoracic spinal cord" Get all the results and reference details, order at left...
10.	Meglumine FDA Link 03/01/1987 - "Arachnoiditis was produced experimentally in male albino ICR mice by intrathecal injection of meglumine iocarmate " 03/01/1978 - "Arachnoiditis resulted after myelography with meglumine iocarmate; however, the risk of arachnoiditis was reduced by diluting the contrast medium" 02/01/1978 - "Arachnoiditis in the animals treated with dilute meglumine iocarmate and gas was significantly less than in those treated with meglumine iocarmate." 02/01/1978 - "Severity of postmyelographic arachnoiditis and concentration of meglumine locarmate in primates." 02/01/1978 - "Intraspinal arachnoiditis and hydrocephalus after lumbar myelography using methylglucamine iocarmate." Get all the results and reference details, order at left...
94 Drugs and Important Bio-Agents and 195 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Debridement 03/01/1989 - "It appears, however, that adequate debridement of these injuries, performed as soon as the patient is stable from any associated injuries, may help to mitigate the late sequelae of arachnoiditis, infection, and pain syndromes in the lower extremities." Get all the results and reference details, order at left...
2.	Biofeedback (Psychology) (Biofeedback) 11/01/1990 - "Efficacy of electroencephalographic biofeedback in autonomovascular dystonia and cerebral arachnoiditis]" Get all the results and reference details, order at left...
3.	Spinal Anesthesia 03/01/1955 - "Spinal arachnoiditis caused by spinal anesthesia; clinical and myelographical study.]" 11/01/1993 - "Despite the simplicity, effectiveness, and safety of spinal anesthesia, arachnoiditis can occur as a complication" 11/01/1993 - "Neuroimaging of arachnoiditis induced by spinal anesthesia." 01/01/1957 - "A case of chronic spinal arachnoiditis with hydromyelia caused by spinal anesthesia.]" 01/01/1957 - "Adhesive arachnoiditis after spinal anesthesia and intra-arachnoid therapy.]" Get all the results and reference details, order at left...
4.	Anesthesia 11/01/1993 - "It is postulated that an untoward reaction to the anesthesia or chemical contamination was the cause of arachnoiditis in our patient" 03/01/1988 - "We studied an atypical patient with recurrent spinal adhesive arachnoiditis nine years after intrathecal anesthesia and the first attack of the disease" 04/05/1955 - "Lumbar anesthesia as a cause of spinal arachnoiditis.]" 12/01/1997 - "However, her neurological function deteriorated 4 months after anesthesia and a magnetic resonance imaging (MRI) study revealed spinal arachnoiditis with multiple subarachnoid cysts at the T5-7 levels" 01/01/2003 - "Neurologic deficits and arachnoiditis following neuroaxial anesthesia." Get all the results and reference details, order at left...
5.	Laminectomy 01/01/1992 - "Laminectomy in lumbar spine surgery often produces disabling adhesive arachnoiditis" 01/01/1984 - "Experimental myelography preceding laminectomy did not increase the risk of arachnoiditis." 01/01/1984 - "Arachnoiditis was as severe after myelography alone as after myelography and laminectomy" 01/01/1984 - "The effect of experimental lumbar myelography and laminectomy on arachnoiditis in monkeys was studied" 01/01/1984 - "Clinical reports have suggested that myelography and laminectomy may produce more arachnoiditis than myelography alone" Get all the results and reference details, order at left...
31 Therapies and Procedures and 77 more articles analyzed in the Research Interface, order at left...

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