|1.||Inoue, Hiroshi: 4 articles (11/2015 - 06/2002)|
|2.||Fujiki, Akira: 3 articles (11/2015 - 09/2004)|
|3.||Sakabe, Masao: 3 articles (11/2015 - 09/2004)|
|4.||Mizumaki, Koichi: 3 articles (11/2015 - 09/2004)|
|5.||Nishida, Kunihiro: 2 articles (11/2015 - 12/2004)|
|6.||Komatsu, Takashi: 2 articles (10/2015 - 04/2003)|
|7.||Sugi, Kaoru: 2 articles (04/2006 - 06/2002)|
|8.||Tsuneda, Takayuki: 2 articles (12/2004 - 09/2004)|
|9.||Nakatani, Yosuke: 1 article (11/2015)|
|10.||Yamaguchi, Yoshiaki: 1 article (11/2015)|
07/01/1989 - "Aprindine significantly decreased the incidence of ventricular tachycardia and fibrillation, compared with control (2/10, p less than 0.01 and 1/10, p less than 0.05, respectively). "
09/01/1999 - "Because aprindine hydrochloride was effective in preventing ventricular tachycardias, we also tested the effect of the drug on WT HERG (I(Kr)) and KvLQT1/KCNE1 (I(Ks)) currents expressed in COS7. "
03/01/1981 - "In conclusion, administration of intravenous aprindine to patients with ventricular tachycardia is helpful in predicting the subsequent response to oral aprindine. "
02/01/1983 - "In this report, we describe our experience with aprindine therapy in seven patients with ventricular tachycardia in whom standard antiarrhythmic agents had proven either ineffective or had caused intolerable side effects. "
02/01/1983 - "Aprindine therapy for refractory ventricular tachycardia."
11/01/1989 - "In conclusion, the administration of a relatively small dose of aprindine and, consequently, low plasma concentration levels, are effective for cardiac tachyarrhythmias in Japanese patients."
01/01/1992 - "Aprindine, however, did not cause anterograde blockade of conduction over the slow AV nodal pathway during tachycardia. "
04/01/1990 - "Aprindine hydrochloride is a potent antiarrhythmic agent against various atrial and ventricular tachyarrhythmias. "
11/01/1989 - "Aprindine hydrochloride (aprindine) was administered orally in 17 Japanese patients with supraventricular or ventricular tachyarrhythmias, and the clinical effects and plasma concentration levels were evaluated. "
11/01/1989 - "[Clinical effects and plasma concentration levels of aprindine hydrochloride in patients with tachyarrhythmias]."
02/01/1999 - "In order to clarify the mechanisms by which the class Ib antiarrhythmic drug aprindine shows efficacy against atrial fibrillation (AF), we examined the effects of the drug on the repolarizing K+ currents in guinea-pig atrial cells by use of patch-clamp techniques. "
06/01/1995 - "However aprindine exaggerated atrial vulnerability in some patients, such that atrial fibrillation was induced."
01/01/1990 - "A 73-year-old man had been treated with Aprindine because of paroxysmal atrial fibrillation. "
04/01/1985 - "Aprindine was given orally to an 88-year-old patient with atrial fibrillation and ventricular premature depolarizations. "
06/01/1995 - "The effects of aprindine on atrial vulnerability were studied in 11 patients; 9 with paroxysmal atrial fibrillation (PAF), and 2 with Wolff-Parkinson-White syndrome, aged 19 to 69 (55.9 +/- 16.5; mean +/- SD). "
03/01/1985 - "With the highest concentration of aprindine tested (0.56 mumol/l), protection against electrically-induced ventricular fibrillation was achieved in 4 out of 6 hearts after 60 min exposure to the drug. "
07/01/1977 - "During the first 30 min of ischaemia 5 of the 22 untreated animals died because of ventricular fibrillation against 1 of the 23 animals pretreated with aprindine (P=0.09). "
08/01/1975 - "The similarly determined ventricular fibrillation threshold was increased from a control value of 2.45 +/- 0.78 mA to a maximum of 5.68 +/- 1.47 mA 30 minutes after aprindine, 5 mg/kg i.v. (P less than .025). "
12/01/1977 - "A study was designed to investigate whether long-term use of aprindine can prevent sudden death from primary ventricular fibrillation. "
03/01/1985 - "Sixty-four patients with a history of ventricular tachycardia and ventricular fibrillation refractory to conventional therapy received aprindine to abolish recurrent episodes of symptomatic ventricular tachycardia. "
07/01/1977 - "It is concluded that aprindine is effective in reducing ventricular arrhythmias and that further investigations on its preventive use after the onset of myocardial infarction are justified."
01/01/1974 - "[Anti-arrhythmic efficacy of aprindine during the acute phase of myocardial infarct]."
04/01/1987 - "Although antiarrhythmic treatment with aprindine of high-risk patients after myocardial infarction does not affect 1 year survival, mortality appears to be delayed; thus there may be a role for short-term treatment before more definitive therapy such as surgery."
10/10/1975 - "Absorption, half-life, and toxicity of oral aprindine in patients with acute myocardial infarction."
12/01/1983 - "[Aprindine, an anti-arrhythmia agent for arrhythmia associated with myocardial infarct]."
|6.||Ouabain (G Strophanthin)
|8.||Adenosine Triphosphate (ATP)
|3.||Electric Countershock (Cardioversion)
|5.||Renal Dialysis (Hemodialysis)