Broca Aphasia (Expressive Aphasia)

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53 relevant articles (5 outcomes, 6 trials/studies) found for this Disease

Description: An aphasia characterized by impairment of expressive language (speech, writing, signs) and relative preservation of receptive language abilities (i.e., comprehension). This condition is caused by lesions of the motor association cortex in the frontal lobe (Broca's area and adjacent cortical and white matter regions). The deficits range from almost complete muteness to a reduction in the fluency and rate of speech. CEREBROVASCULAR ACCIDENTS (in particular INFARCTION, MIDDLE CEREBRAL ARTERY) are a relatively common cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp478-9)

Also Known As:

Expressive Aphasia; Aphasia, Expressive; Motor Aphasia; Aphasia, Broca; Aphasia, Anterior; Aphasia, Ataxic; Aphasia, Frontocortical; Dysphasia, Broca's; Verbal Aphasia Syndrome; Anterior Aphasia; Anterior Aphasias; Aphasia Syndrome, Verbal; Aphasia Syndromes, Verbal; Aphasias, Anterior; Aphasias, Ataxic; Aphasias, Broca; Aphasias, Frontocortical; Ataxic Aphasia; Ataxic Aphasias; Broca Aphasias; Broca Dysphasia; Broca's Dysphasia; Dysphasia, Brocas; Frontocortical Aphasia; Frontocortical Aphasias; Nonfluent Aphasia; Syndrome, Verbal Aphasia; Syndromes, Verbal Aphasia; Verbal Aphasia Syndromes; Agrammatism; Aphasia, Motor; Aphasia, Nonfluent; Dysphasia, Broca

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3405

Neurologic Manifestations: 2874

Neurobehavioral Manifestations: 295

Communication Disorders: 83

Language Disorders: 73

Speech Disorders: 89

Aphasia: 534

Broca Aphasia: 53

Signs and Symptoms Pathological Conditions

Signs and Symptoms

Neurologic Manifestations: 2874

Neurobehavioral Manifestations: 295

Communication Disorders: 83

Language Disorders: 73

Speech Disorders: 89

Aphasia: 534

Broca Aphasia: 53

Related Diseases

1.	Stroke (Strokes)
2.	Hemiplegia (Spastic Hemiplegia)
3.	Paresis (Hemiparesis)
4.	Seizures (Seizure)
5.	Syndrome
30 Diseases and 28 more articles analyzed in the Research Interface, order at left...

Experts

1.	Luo, Wei-Ping: 1 article (03/2008)
2.	Stadie, Nicole: 1 article (03/2008)
3.	Tan, Ji-lin: 1 article (03/2008)
4.	De Bleser, Ria: 1 article (03/2008)
5.	Swoboda-Moll, Maria: 1 article (03/2008)
6.	Burchert, Frank: 1 article (03/2008)
7.	Huang, Hong-ying: 1 article (03/2008)
8.	Schröder, Astrid: 1 article (03/2008)
9.	Postler, Jenny: 1 article (03/2008)
10.	Lorenz, Antje: 1 article (03/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Broca Aphasia:

1.	Bromocriptine (Parlodel)FDA LinkGeneric 12/01/1995 - "We carried out a double-blind and placebo-controlled study of the efficacy of bromocriptine in the treatment of nonfluent aphasia" 01/01/2001 - "OBJECTIVE: Because studies have shown some positive effects of the dopaminergic agent bromocriptine for improving verbal production in patients with nonfluent aphasia, we examined its effect in a patient with an atypical form of crossed nonfluent aphasia from a right hemisphere lesion" 09/01/2000 - "An open-label trial of bromocriptine in nonfluent aphasia: a qualitative analysis of word storage and retrieval." 12/01/1995 - "A randomized, double-blind, placebo-controlled study of bromocriptine in nonfluent aphasia." 08/01/1992 - "An open-label trial of bromocriptine in nonfluent aphasia." Get all the results and reference details, order at left...
2.	DNA Transposable Elements (Element, IS)IBA 07/01/1995 - "These steps led to significant improvement in the performance of agrammatic aphasics, a result that is incompatible with the claim that the content of nonlexical elements is lost in agrammatism." 02/01/2003 - "These results contrast with the predictions of the tree-pruning hypothesis, suggesting that the nearer to the end of the clause a functional element is located, the better it is preserved in Korean agrammatism." Get all the results and reference details, order at left...
3.	Dopamine (Intropin)FDA LinkGeneric 02/01/2004 - "While an administration of anti-coagulant, diuretics, and dopamine relieved his respiratory distress and right hemiplegia, severe motor aphasia persisted" Get all the results and reference details, order at left...
4.	DiureticsIBA 02/01/2004 - "While an administration of anti-coagulant, diuretics, and dopamine relieved his respiratory distress and right hemiplegia, severe motor aphasia persisted" Get all the results and reference details, order at left...
5.	Metrizamide FDA Link 03/01/1983 - "Transient motor aphasia following metrizamide myelography." 08/01/1980 - "Two cases of transient motor aphasia after cervical myelography with Metrizamide are described" 08/01/1980 - "Motor aphasia after cervical myelography with metrizamide (author's transl)]" Get all the results and reference details, order at left...
6.	Complement System Proteins (Complement)IBA 05/15/2000 - "Simulations are reported of a significant range of psycholinguistic parsing phenomena in both normal and aphasic speakers of English: (i) various effects of linguistic complexity (single versus double, center versus right-hand self-embeddings of relative clauses; the difference between relative clauses with subject and object extraction; the contrast between a complement clause embedded within a relative clause versus a relative clause embedded within a complement clause); (ii) effects of local and global ambiguity, and of word-class and syntactic ambiguity (including recency and length effects); (iii) certain difficulty-of-reanalysis effects (contrasts between local ambiguities that are easy to resolve versus ones that lead to serious garden-path effects); (iv) effects of agrammatism on parsing performance, in particular the performance of various groups of aphasic patients on several sentence types." 02/01/2006 - "In this paper, we investigate the performance of a Greek-English bilingual patient with Broca's aphasia and mild agrammatism on the placement of CP, MoodP, AspectP, and NegP-related adverbs, labeled specifier-type adverbs, and VP-related adverbs, labeled complement-type adverbs, by means of a constituent ordering task and a grammaticality judgment task" Get all the results and reference details, order at left...
7.	Carbon MonoxideIBA 07/01/1989 - "The results argue against any global theory of agrammatism that attempts to attribute all agrammatic speech and co-occurring syntactic comprehension deficits to the same source." 06/01/1984 - "Current theories of agrammatism do not provide a clear explanation for the co-occurrence of omission of grammatical markers and main verbs in this disorder" Get all the results and reference details, order at left...
8.	Oseltamivir (Tamiflu)FDA Link 01/01/2008 - "CASE PRESENTATION: A previously healthy 35-year-old man presented with acute progressive tetraplegia, transcortical motor aphasia and a mild decrease in his consciousness during his recovery after receiving oseltamivir phosphate treatment, and influenza type A antiviral medication" Get all the results and reference details, order at left...
9.	Dopamine Agonists (Dopamine Agonist)IBA 09/01/2000 - "Bromocriptine, a dopamine agonist, was tested on four patients, two men and two women, with nonfluent aphasia" Get all the results and reference details, order at left...
10.	Biological Markers (Surrogate Marker)IBA 12/01/2008 - "Apraxia of speech and nonfluent aphasia: a new clinical marker for corticobasal degeneration and progressive supranuclear palsy." Get all the results and reference details, order at left...
25 Drugs and Important Bio-Agents and 37 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Speech Therapy (Therapy, Speech) 11/01/1989 - "The patient improved slightly during hospitalization and was discharged on the sixth hospital day with a moderate expressive aphasia for which she received intensive speech therapy." 01/01/1963 - "A case of severe developmental motor aphasia with psychotic symptoms successfully treated by speech therapy." 03/01/1951 - "Group speech therapy for motor aphasia and dysarthria." Get all the results and reference details, order at left...
2.	Drug Therapy (Chemotherapy) 01/01/1994 - "Rapid resolution following chemotherapy of Broca's dysphasia due to recurrent anaplastic astrocytoma." 01/01/1997 - "After the second course of chemotherapy, partial seizures including transient motor aphasia, tonic finger movement, and loss of consciousness were observed" 11/01/2007 - "Since Albert reported that bromocriptine may improve language deficits in patients with nonfluent aphasia, pharmacotherapy for aphasia is noted" Get all the results and reference details, order at left...
3.	Sign Language 09/01/2003 - "Oral language was not fluent, but sign language was quite fluent with a rich vocabulary, but with semantic paraphasias, agrammatism and without self-criticism for his own mistakes" 02/01/1999 - "She had oromotor apraxia and partial expressive aphasia since childhood, and she was able to partially communicate through elementary sign language" Get all the results and reference details, order at left...
4.	Language Therapy (Language Training) 09/01/1984 - "belongs to Type F 3 who recovered from typical Broca aphasia after language training for four years" 03/01/2008 - "CONCLUSION: Tiaoshen Fuyin acupuncture therapy combined with language training can significantly improve language function and increase life quality in the patient of cerebral infarction-induced Broca aphasia." 03/01/2008 - "Clinical observation on treatment of cerebral infarction-induced broca aphasia by Tiaoshen Fuyin acupuncture therapy combined with language training]" Get all the results and reference details, order at left...
5.	Hemispherectomy 01/01/2004 - "Left functional hemispherectomy resulted in expressive aphasia" Get all the results and reference details, order at left...
14 Therapies and Procedures and 18 more articles analyzed in the Research Interface, order at left...

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