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Aphasia (Dysphasia)

A cognitive disorder marked by an impaired ability to comprehend or express language in its written or spoken form. This condition is caused by diseases which affect the language areas of the dominant hemisphere. Clinical features are used to classify the various subtypes of this condition. General categories include receptive, expressive, and mixed forms of aphasia.
Also Known As:
Dysphasia; Alogia; Logamnesia; Acquired Aphasia; Syntactical Aphasia; Anepia; Aphasia, Ageusic; Aphasia, Auditory Discriminatory; Aphasia, Commisural; Aphasia, Functional; Aphasia, Global; Aphasia, Graphomotor; Aphasia, Intellectual; Aphasia, Mixed; Aphasia, Post-Ictal; Aphasia, Post-Traumatic; Aphasia, Progressive; Aphasia, Semantic; Aphasia, Syntactical; Dejerine-Lichtheim Phenomenon; Dysphasia, Global; Lichtheim's Sign; Logagnosia; Logasthenia; Ageusic Aphasia; Ageusic Aphasias; Alogias; Anepias; Aphasia, Post Ictal; Aphasia, Post Traumatic; Aphasias, Commisural; Auditory Discriminatory Aphasia; Auditory Discriminatory Aphasias; Commisural Aphasia; Commisural Aphasias; Deafness, Word; Dejerine Lichtheim Phenomenon; Discriminatory Aphasia, Auditory; Discriminatory Aphasias, Auditory; Functional Aphasia; Functional Aphasias; Global Aphasia; Global Aphasias; Global Dysphasia; Global Dysphasias; Graphomotor Aphasia; Graphomotor Aphasias; Intellectual Aphasia; Intellectual Aphasias; Lichtheim Sign; Lichtheims Sign; Logagnosias; Logamnesias; Logasthenias; Mixed Aphasia; Mixed Aphasias; Phenomenon, Dejerine-Lichtheim; Post-Ictal Aphasia; Post-Ictal Aphasias; Post-Traumatic Aphasia; Post-Traumatic Aphasias; Progressive Aphasia; Progressive Aphasias; Semantic Aphasia; Semantic Aphasias; Sign, Lichtheim's; Syntactical Aphasias; Aphasia, Acquired; Word Deafness
Networked: 2272 relevant articles (251 outcomes, 435 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Stroke (Strokes)
2. Anomia (Dysnomia)
3. Paresis (Hemiparesis)
4. Confusion (Bewilderment)
5. Epilepsy (Aura)

Experts

1. Fridriksson, Julius: 27 articles (12/2022 - 09/2002)
2. Cherney, Leora R: 23 articles (01/2022 - 04/2008)
3. Rose, Miranda L: 22 articles (12/2022 - 05/2013)
4. Pulvermüller, Friedemann: 22 articles (01/2022 - 11/2005)
5. Marangolo, Paola: 22 articles (04/2021 - 09/2011)
6. Kiran, Swathi: 20 articles (01/2022 - 04/2013)
7. Meinzer, Marcus: 19 articles (12/2022 - 08/2004)
8. Worrall, Linda: 16 articles (12/2022 - 01/2003)
9. Caltagirone, Carlo: 16 articles (04/2021 - 01/2012)
10. Godecke, Erin: 15 articles (12/2022 - 12/2012)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aphasia:
1. 2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
2. Donepezil (Aricept)FDA LinkGeneric
3. salicylhydroxamic acid (SHAM)IBA
4. Cholinergic Agents (Cholinergics)IBA
5. TabletsIBA
6. Piracetam (Nootropil)IBA
7. Dextroamphetamine (Dexedrine)FDA LinkGeneric
8. cortexinIBA
9. Biomarkers (Surrogate Marker)IBA
10. Nootropic Agents (Nootropics)IBA

Therapies and Procedures

1. Therapeutics
01/01/2017 - "Treatment with DP alone and combined with LLR therapy induced marked improvement in aphasia and communication deficits as well as in selected measures of connected speech production, and phrase repetition. "
01/01/2017 - "Constraint-induced aphasia therapy (CIAT) has proven effective in patients with subacute and chronic forms of aphasia. "
01/01/2006 - "Thus, we here suggest that the non-language communication channels of Wernicke's aphasia patients be channeled and utilized in their functional rehabilitation: Specifically, we suggest that therapy for Wernicke's aphasia patients should consist of placing patients in real or simulated important functional situations--e.g., buying food, taking transport--and let the patients train and learn to use and hone their non-language communication means and skills for improved practical functioning."
01/01/2023 - "Similarly, significantly more improvement was seen in the communication domain of SAQOL39g in the study group (2.03 ± 0.17) compared to the control group (1.14 ± 0.45).Conclusion: Use of the Jellow app may be a beneficial adjunct to stimulation therapy for improving linguistic abilities and quality of life in persons with chronic Broca's aphasia.IMPLICATIONS FOR REHABILITATIONFollowing are the implications of this study in the rehabilitation of persons with chronic Broca's Aphasia:• Multimodality in therapy approach in traditional stimulation therapy is beneficial.• AAC Apps like the Jellow app can be used as an adjunct to the traditional stimulation approach of language intervention which facilitates the language abilities like spontaneous speech, repetition, and naming.• Language improvement due to rehabilitation is beneficial in improving the quality of life in this population.• The caregivers must be involved in the therapy program as they act as communication partners and can repeat the therapy tasks at home.• Similar type of study is warranted in a larger population so that people with chronic Broca's aphasia may get the benefit of the latest technology which may be cheaper and easier to use."
01/01/2016 - "This study investigates the effects of a purpose-built gesture therapy technology for people with severe aphasia: GeST+. Study outcomes show significant improvement in gesture production abilities for adults with severe aphasia following computer intervention. "
2. Transcranial Direct Current Stimulation
3. Language Therapy (Language Training)
4. Transcranial Magnetic Stimulation
5. Speech Therapy (Therapy, Speech)