Aortopulmonary Septal Defect

A developmental abnormality in which the spiral (aortopulmonary) septum failed to completely divide the TRUNCUS ARTERIOSUS into ASCENDING AORTA and PULMONARY ARTERY. This abnormal communication between the two major vessels usually lies above their respective valves (AORTIC VALVE; PULMONARY VALVE).

Also Known As:

Aorticopulmonary Septal Defect; Aorticopulmonary Septal Defects; Aortopulmonary Septal Defects; Septal Defect, Aorticopulmonary; Septal Defect, Aortopulmonary; Septal Defects, Aorticopulmonary; Septal Defects, Aortopulmonary

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Aortic Coarctation

Experts

1.	Feng, Yuan: 1 article (01/2014)
2.	Li, Xiao: 1 article (01/2014)
3.	Zhu, Da: 1 article (01/2014)
4.	Puri, Prem: 1 article (02/2008)
5.	Sato, Hideaki: 1 article (02/2008)
6.	Sugimoto, Kaoru: 1 article (02/2008)
7.	Takayasu, Hajime: 1 article (02/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aortopulmonary Septal Defect:

1.	Coenzyme A (CoA)IBA 04/01/1997 - "Two infants with aorticopulmonary septal defect (APSD) and coarctation of the aorta (CoA) underwent primary surgical repair and their aortic arches were reconstructed in a manner of end-to-end anastomosis. "
2.	nitrofenIBA 02/01/2008 - "In addition, the GATA4/GATA6 double heterozygous mutant embryo model displayed a spectrum of cardiovascular malformations similar to those seen in human CDH and nitrofen-induced animal models, including ventricular and aortopulmonary septal defects and thin ventricular myocardium. "

Therapies and Procedures

1.	Septal Occluder Device 01/01/2014 - "Transcatheter closure of late-onset residual aortopulmonary septal defect using a muscular ventricular septal occluder."
2.	Sutures (Suture) 09/01/1981 - "Operative techniques included ligation, direct suture, and patch closure of the aortopulmonary septal defect. "
3.	Ligation 09/01/1981 - "Operative techniques included ligation, direct suture, and patch closure of the aortopulmonary septal defect. "
4.	Cardiopulmonary Bypass (Heart-Lung Bypass) 10/01/1991 - "In a 20-days old girl, aortopulmonary septal defect (total defect type) was closed by transaortic patch repair with cardiopulmonary bypass (CPB). "