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Description: A developmental abnormality in which the spiral (aortopulmonary) septum failed to completely divide the TRUNCUS ARTERIOSUS into ASCENDING AORTA and PULMONARY ARTERY. This abnormal communication between the two major vessels usually lies above their respective valves (AORTIC VALVE; PULMONARY VALVE).
Also Known As:| 1. | Coenzyme A (CoA)IBA
04/01/1997
- "Two infants with aorticopulmonary septal defect (APSD) and coarctation of the aorta (CoA) underwent primary surgical repair and their aortic arches were reconstructed in a manner of end-to-end anastomosis"
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| 2. | nitrofen (TOK)IBA
02/01/2008
- "In addition, the GATA4/GATA6 double heterozygous mutant embryo model displayed a spectrum of cardiovascular malformations similar to those seen in human CDH and nitrofen-induced animal models, including ventricular and aortopulmonary septal defects and thin ventricular myocardium"
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