Aortic Valve Stenosis (Aortic Stenosis)

A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
Also Known As:
Aortic Stenosis; Aortic Valve Stenoses; Stenoses, Aortic; Stenoses, Aortic Valve; Stenosis, Aortic; Stenosis, Aortic Valve; Valve Stenoses, Aortic; Valve Stenosis, Aortic
Networked: 2889 relevant articles (94 outcomes, 341 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypertrophy
2. Heart Failure
3. Coronary Disease (Coronary Heart Disease)
4. Mitral Valve Insufficiency (Mitral Regurgitation)
5. Hypoplastic Left Heart Syndrome


1. Pibarot, Philippe: 37 articles (12/2015 - 02/2003)
2. Wachtell, Kristian: 32 articles (12/2015 - 04/2007)
3. Gerdts, Eva: 29 articles (11/2015 - 04/2007)
4. Ray, Simon: 25 articles (12/2015 - 04/2007)
5. Dumesnil, Jean G: 24 articles (12/2015 - 02/2003)
6. Boman, Kurt: 23 articles (12/2015 - 04/2007)
7. Mathieu, Patrick: 22 articles (12/2015 - 01/2008)
8. Rossebø, Anne B: 21 articles (11/2015 - 04/2007)
9. Cramariuc, Dana: 18 articles (11/2015 - 02/2008)
10. Pedersen, Terje R: 18 articles (11/2015 - 08/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Aortic Valve Stenosis:
1. DobutamineFDA LinkGeneric
2. Brain Natriuretic Peptide (Natrecor)FDA Link
3. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
4. OxygenIBA
5. Simvastatin (Zocor)FDA LinkGeneric
6. ezetimibe (Zetia)FDA Link
7. LDL CholesterolIBA
8. Coarctation of the aortaIBA
9. Lipoproteins (Lipoprotein)IBA
10. Lipoprotein(a)IBA

Therapies and Procedures

1. Balloon Dilation
2. Surgical Instruments (Clip)
3. Bioprosthesis
4. Prostheses and Implants (Prosthesis)
11/01/2007 - "Due to improvement in surgical techniques and better prosthesis, aortic valve surgery can now be offered at low risk to a selected group of asymptomatic patients with severe aortic stenosis. "
07/01/2010 - "This prospective study aimed to determine to what extent clinical symptoms and neurohumoral activation are improved in patients with severe aortic valve stenosis after transcatheter aortic valve implantation (TAVI) with the CoreValve prosthesis. "
08/18/2015 - "Despite the higher device success rate with the balloon-expandable valve, 1-year follow-up of patients in CHOICE (Randomized Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: Medtronic CoreValve Versus Edwards SAPIEN XT Trial), with limited statistical power, revealed clinical outcomes after transfemoral transcatheter aortic valve replacement with both balloon- and self-expandable prostheses that were not statistically significantly different. "
09/01/2014 - "The study aim was to compare the hemodynamic performance of the Trifecta valve with that of the Freestyle valve in patients with an aortic annulus ≤ 2.3 cm. Between September 2011 and September 2013, a total of 40 patients with pure aortic stenosis and native aortic annulus diameter ≤ 2.3 cm was randomized to receive either a St. Jude Medical Trifecta stented prosthesis (n = 20) or a Medtronic Freestyle stentless prosthesis (n = 20). "
11/01/2013 - "Effect of the prosthesis-patient mismatch on long-term clinical outcomes after isolated aortic valve replacement for aortic stenosis: a prospective observational study."
5. Catheters