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Separation Anxiety (Separation Anxiety Disorder)

Anxiety experienced by an individual upon separation from a person or object of particular significance to him.
Also Known As:
Separation Anxiety Disorder; Anxiety, Separation; Anxiety Disorder, Separation
Networked: 140 relevant articles (10 outcomes, 28 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Phobic Disorders (Phobia)
2. Anxiety Disorders (Anxiety Disorder)
3. Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive)
4. Panic Disorder (Panic Attack)
5. Attention Deficit and Disruptive Behavior Disorders (Oppositional Defiant Disorder)

Experts

1. Birmaher, Boris: 7 articles (03/2015 - 04/2003)
2. Pini, Stefano: 7 articles (01/2014 - 08/2005)
3. Walkup, John T: 6 articles (03/2015 - 12/2008)
4. Muti, Matteo: 6 articles (12/2012 - 08/2005)
5. Abelli, Marianna: 6 articles (12/2012 - 08/2005)
6. Compton, Scott N: 5 articles (03/2015 - 12/2008)
7. Albano, Anne Marie: 5 articles (03/2015 - 12/2008)
8. Cassano, Giovanni B: 5 articles (12/2012 - 08/2005)
9. Gesi, Camilla: 5 articles (12/2012 - 09/2005)
10. McCracken, James: 4 articles (03/2015 - 01/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Separation Anxiety:
1. Sertraline (Zoloft)FDA LinkGeneric
01/01/2013 - "Data were from a subset of youth (N = 438; 7-17 years of age) who participated in the Child/Adolescent Anxiety Multimodal Study (CAMS), a multi-site, randomized controlled trial that examined the relative efficacy of cognitive-behavioral therapy (CBT; Coping Cat), medication (sertraline [SRT]), their combination, and pill placebo for the treatment of separation anxiety disorder, generalized anxiety disorder, and social phobia. "
01/01/2010 - "To present the design, methods, and rationale of the Child/Adolescent Anxiety Multimodal Study (CAMS), a recently completed federally-funded, multi-site, randomized placebo-controlled trial that examined the relative efficacy of cognitive-behavior therapy (CBT), sertraline (SRT), and their combination (COMB) against pill placebo (PBO) for the treatment of separation anxiety disorder (SAD), generalized anxiety disorder (GAD) and social phobia (SoP) in children and adolescents. "
04/01/2014 - "We sought to examine predictors and moderators of treatment outcomes among 488 youths ages 7-17 years (50% female; 74% ≤ 12 years) meeting Diagnostic and Statistical Manual of Mental Disorders (4th ed., text rev.; American Psychiatric Association, 2000) criteria for diagnoses of separation anxiety disorder, social phobia, or generalized anxiety disorder who were randomly assigned to receive either cognitive behavioral therapy (CBT), sertraline (SRT), their combination (COMB), or medication management with pill placebo (PBO) in the Child/Adolescent Anxiety Multimodal Study (CAMS). "
03/01/2015 - "Participants ages 7 to 17 years (mean = 10.7 years) meeting the DSM-IV criteria for 1 or more of the following disorders: separation anxiety disorder, generalized anxiety disorder, or social phobia were randomized (2:2:2:1) to cognitive-behavioral therapy (CBT, n = 139), sertraline (SRT, n = 133), a combination of both (COMB, n = 140), or pill placebo (PBO, n = 76). "
12/25/2008 - "In this randomized, controlled trial, we assigned 488 children between the ages of 7 and 17 years who had a primary diagnosis of separation anxiety disorder, generalized anxiety disorder, or social phobia to receive 14 sessions of cognitive behavioral therapy, sertraline (at a dose of up to 200 mg per day), a combination of sertraline and cognitive behavioral therapy, or a placebo drug for 12 weeks in a 2:2:2:1 ratio. "
2. Fluvoxamine (Luvox)FDA LinkGeneric
3. Fluoxetine (Prozac)FDA LinkGeneric
4. Clomipramine (Anafranil)FDA LinkGeneric
5. Midazolam (Versed)FDA LinkGeneric
6. Imipramine (Janimine)FDA LinkGeneric
7. Hydrocortisone (Cortisol)FDA LinkGeneric
8. Carbon MonoxideIBA
9. A-factor (Streptomyces)IBA
10. Dihydrotachysterol (AT 10)IBA

Therapies and Procedures

1. Anesthesia
2. Drug Therapy (Chemotherapy)
3. Premedication
4. Therapeutics
5. Injections