Antipruritics

07/01/2006 - "An animal model of AD-like pruritus would contribute to a better understanding of AD and could lead to the development of safe and effective antipruritic agents. "
10/15/2019 - "Thus, our results showed that the PUL extract could be effective for alleviating pruritus, and the antipruritic effects were exerted probably via the inhibition of the TSLP pathway in peripheral sensory neurons governing the itch sensation in AD."
06/01/2022 - "The antipruritic efficacy of these agents has been observed across multiple disorders with disparate etiologies, suggesting the potential utility of this class to provide a unified approach to chronic pruritus treatment. "
01/01/2015 - "Appropriate animal models of pathological itching are needed for pharmacological evaluation of the antipruritic efficacy of chemical agents. "
01/01/2015 - "It was difficult to investigate the pathophysiology of itching and to evaluate the antipruritic efficacy of chemical agents in the early 1990 s. "

01/01/2015 - "One of the most common causes of canine itch is that associated with atopic dermatitis, and there is randomized controlled trial grade evidence of the efficacy of several antipruritic interventions. "
11/01/2021 - "In-vivo study demonstrated potent antipruritic efficacy of transdermal gel in atopic dermatitis such as induced lesions compared to HHCL gel. "
10/01/2018 - "Use of antipruritic and rehydrating foams on localized lesions of atopic dermatitis in dogs: a small-scale pilot and comparative double-blinded study."
05/01/2000 - "The present study indicates that BN has an inhibitory effect on itch, and may be a useful antipruritic drug for atopic dermatitis."
03/07/2023 - "We also, summarize the new emerging antipruritic drugs in atopic dermatitis."

01/01/2022 - "Conclusion: Our results demonstrate that CB2R plays a pivotal role in the pathophysiology of psoriasis, providing a new potential target for anti-inflammatory and antipruritic drugs."
11/01/2022 - "Efficient antipruritic therapies should be developed and be made available for patients with psoriasis."
01/01/2007 - "Limited knowledge of pruritus origin in psoriasis is responsible for the lack of the effective antipruritic treatments for psoriatics. "
10/01/2017 - "Antihistamines of the first and second generations seem to be effective in reducing itch in patients with psoriasis, albeit the antipruritic effect is rather moderate. "
05/25/2021 - "Our study delineated a new role of TRPV4 in psoriasis and emphasized the antipruritic effect of cimifugin, which opened a new avenue to itch management in psoriasis."

01/01/2017 - "Our aim was to evaluate the safety and antipruritic efficacy of application of this cream in volunteers with and without skin diseases. "
03/22/2022 - "Clinical Guidelines for the Use of Antipruritic Drugs in the Control of the Most Frequent Pruritic Skin Diseases in Dogs."
01/01/2010 - "Statistically significant differences (P = 0.05) of the parameters assessed were found after secondary dermatoses treatment, and after every two weeks of antipruritic and anti-inflammatory treatment."
06/01/1995 - "[Pharmacotherapeutic use of antipruritic drugs in skin diseases]."
07/15/1964 - "[TOPICAL TREATMENT OF DERMATOSES WITH A NEW ANTIPRURITIC AGENT IN CLINICAL PRACTICE]."

12/01/2019 - "The Neuromodulatory Effect of Antipruritic Treatment of Chronic Prurigo."
04/01/2019 - "Under the experimental conditions of the study, aprepitant, 80 mg daily for 4 weeks, did not have an antipruritic effect in patients with chronic prurigo. "
11/01/2008 - "Antipruritic effect of cyclosporine microemulsion in prurigo nodularis: results of a case series."
10/01/1999 - "Naltrexone was of high antipruritic effect in 9 of 17 cases of prurigo nodularis and contributed to healing of the skin lesions. "
01/01/2015 - "In fact, in recent case reports and case series, SP antagonists demonstrated a significant antipruritic effect in acute and chronic pruritus such as drug-induced pruritus, paraneoplastic pruritus, prurigo nodularis, cutaneous T-cell lymphoma, and brachioradial pruritus. "