Antinuclear Antibodies

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2955 relevant articles (54 outcomes, 180 trials/studies) found for this Bio-Agent

Description: Autoantibodies directed against various nuclear antigens including DNA, RNA, histones, acidic nuclear proteins, or complexes of these molecular elements. Antinuclear antibodies are found in systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

Also Known As:

Antibodies, Antinuclear; Antinuclear Antibody; Antinuclear Factor; Anti DNA Antibodies; Antibodies, Anti DNA; Antibodies, Fluorescent Antinuclear; Antibody, Antinuclear; Antinuclear Antibodies, Fluorescent; Factor, Antinuclear; Factors, Antinuclear; Anti-DNA Antibodies; Antibodies, Anti-DNA; Antinuclear Factors; Fluorescent Antinuclear Antibodies

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 58433

Globulins: 305

Serum Globulins: 74

Immunoglobulins: 20136

Antibodies: 77322

Autoantibodies: 14185

Antinuclear Antibodies: 2955

SS-A antibodies: 192

MIB-1 antibody: 112

SS-B antibodies: 100

antiperinuclear factor: 70

Jo-1 antibody: 24

anti-extractable nuclear antigen antibodies: 12

anti-quadruplex DNA scFv

deoxyribonucleoprotein antibodies

mouse 3H9 protein

Experts

1.	Yung, Susan: 3 articles (02/2008 - 05/2002)
2.	Russell, Anthony S: 2 articles (11/2008 - 04/2003)
3.	Schaeverbeke, T: 2 articles (05/2008 - 10/2001)
4.	Chan, Tak Mao: 2 articles (02/2008 - 11/2005)
5.	Medsger, Thomas A: 2 articles (01/2007 - 07/2003)
6.	Martini, Alberto: 2 articles (09/2005 - 03/2005)
7.	Bozzola, Elena: 2 articles (09/2005 - 03/2005)
8.	Ravelli, Angelo: 2 articles (09/2005 - 03/2005)
9.	Novarini, Cristina: 2 articles (09/2005 - 03/2005)
10.	Pistorio, Angela: 2 articles (09/2005 - 03/2005)

Related Diseases

1.	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/01/2007 - "Immunofluorescence microscopy is superior to fluorescent beads for detection of antinuclear antibody reactivity in systemic lupus erythematosus patients." 09/01/2004 - "OBJECTIVES: To study associations between antinuclear antibodies (ANA) and signs/symptoms in patients with systemic lupus erythematosus (SLE). " 01/01/2002 - "Several excellent animal models for systemic lupus erythematosus are available to study the pathogenetic mechanisms of anti-DNA antibodies, immunological mechanisms for their origin and the influence of susceptibility genes for the development of anti-DNA antibodies. " 08/25/2001 - "The aim of this study is to prepare magnetic poly(2-hydroxyethylmethacrylate) (mPHEMA) beads and to investigate their utility for the removal of anti-DNA antibodies from systemic lupus erythematosus (SLE) patient plasma. " 02/01/1996 - "The ELISA procedure established in this study is showed to be a available method to detect anti-DNA antibodies associated with renal disease in patients with systemic lupus erythematosus." Order ALL the reference details at left...
2.	Proteinuria 05/01/1978 - "Such treated mice had reduced anti-DNA antibodies, reduced proteinuria, and improved survival. " 05/01/1986 - "Similar to our past studies, this treatment resulted in a marked prolongation of survival, decrease in proteinuria, and decrease in serum anti-DNA antibodies compared with untreated littermate controls. " 12/01/2008 - "Eight years after onset of TA, SLE was diagnosed on the basis of clinical and laboratory findings, including proteinuria, hematological and immunological abnormalities, high titer of antinuclear antibody, and a positive lupus band test on the skin. " 11/01/2007 - "Anaemia was noted in seven patients, raised ALT in three, hypergammaglobulnaemia in three, proteinuria in one and three of six patients positive of antinuclear antibodies (ANA). " 05/01/2007 - "However, development of autoimmune (AI)-reactions and the increase in the sera anti-DNA antibodies (Abs) and in the abzyme activities in pregnant and lactating mice do not associate with SLE visible markers and proteinuria. " Order ALL the reference details at left...
3.	Arthritis (Polyarthritis) 01/01/2008 - "The remaining clinical and laboratory variables, such as arthritis severity index, presence of radiographic erosions and antinuclear antibody positivity, were not associated with MBL2 genotypes. " 07/01/2006 - "Antinuclear antibodies (ANA; by indirect immunofluorescence, HEp >/= 1/80) were detected in patients with oligoarthritis (81%) and polyarthritis without RF (79%). " 01/01/2006 - "Ten of this patient group had oligo-arthritis, 16 were antinuclear antibody (ANA) positive, 16 were girls. " 04/01/2005 - "The diagnosis is mainly based on typical clinical manifestations, the history of arthritis and positive antinuclear antibodies. " 08/15/2003 - "As compared with group 2, patients in group 3 were less frequently antinuclear antibody positive and had a more severe arthritis and a different distribution of joint involvement. " Order ALL the reference details at left...
4.	Syndrome 01/01/1986 - "A study was made of the presence of antinuclear antibodies to Ro, La, nDNA, RNP and Sm in 18 patients with Sjögren's disease (SD) and in 13 patients with Sjögren's syndrome (SS). " 02/29/2008 - "However, evidence to date has revealed associated side effects, including antinuclear antibody induction and development of a lupus-like syndrome. " 01/01/2007 - "Finally, some extraocular explorations such as accessory gland biopsy or serum antinuclear antibody dosage may be useful for assessing the diagnosis of Sjögren's syndrome." 05/01/2005 - "Skin biopsy specimen and immunofluorescence findings led us to suspect neonatal lupus, a diagnosis confirmed by positivity for anti-Sjörgen syndrome and antinuclear antibodies both in the child and her mother. " 09/01/2004 - "RESULTS: Prévalence anti-Ku is low (1/3493 case of antinuclear antibodies) and association is possible with in a myositic process through variable auto-immune contexts (overlap syndrome) of relative good preview. " Order ALL the reference details at left...
5.	Rheumatoid Arthritis 03/01/1977 - "Skin immunofluorescence studies are helpful in differential diagnosis when patients with a clinical picture of rheumatoid arthritis present with serum antinuclear antibodies and lupus erythematosus cells. " 07/01/1982 - "Studies of antinuclear antibodies in rheumatoid arthritis." 01/01/2005 - "[immunological and serological tests for diagnosis of rheumatoid arthritis: antinuclear antibodies]" 07/01/1998 - "Examinations of 121 patients with rheumatoid arthritis (RA) included immunological testing for antinuclear antibodies (ANA), lymphocyte blastogenesis test, and leukocyte migration inhibition test and functional cardiological examinations (ECG and EchoCG). " 10/01/1996 - "Positivity for antinuclear antibody in patients with advanced rheumatoid arthritis." Order ALL the reference details at left...

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Antibodies
3.	Rheumatoid Factor
4.	Antigen-Antibody Complex (Immune Complex)
5.	Complement System Proteins (Complement)
6.	Prednisone (Sone)
7.	Antigens
8.	Urea (Carbamide)
9.	Azathioprine (Imuran)
10.	Immunoglobulin G (IgG)

Related Therapies and Procedures

1.	Plasma Exchange
2.	Aftercare (After-Treatment)
3.	Transplants (Transplant)
4.	PUVA Therapy
5.	Injections

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